We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
LGC Clinical Diagnostics

STRECK LABORATORIES

Develops and manufactures products for clinical and research laboratories in biotechnology, clinical controls, hemato... read more Featured Products: More products

Download Mobile App




Events

09 Apr 2024 - 12 Apr 2024
15 Apr 2024 - 17 Apr 2024
23 Apr 2024 - 26 Apr 2024

Whole Cell Glycated Hemoglobin Control Calibrated for Most Popular Instruments

By LabMedica International staff writers
Posted on 22 Dec 2014
Print article
Streck\'s A1c-Cellular control
The A1c-Cellular control (Photo courtesy of STRECK LABORATORIES)
Laboratories that measure glycated hemoglobin (HbA1c) now have available a whole blood cell control material that has been calibrated for several major autoanalyzers.

HbA1c is a derivative of hemoglobin that is formed nonenzymically by reaction at the N terminus of the protein molecule with glucose. In the normal adult human such derivatives constitute a few percent of the total erythrocyte hemoglobin, the most abundant being hemoglobin A1c, which increases several fold in concentration in diabetes mellitus, and is assayed to monitor control of diabetes. Once a hemoglobin molecule is glycated, it remains that way. A buildup of glycated hemoglobin within the red cell, therefore, reflects the average level of glucose to which the cell has been exposed during its life-cycle. Measuring glycated hemoglobin assesses the effectiveness of therapy by monitoring long-term serum glucose regulation. The HbA1c level is proportional to average blood glucose concentration over the previous four weeks to three months.

The American Diabetes Association and the World Health Organization have suggested that an HbA1c level of 6.5% or more is an indicator of type II diabetes and an HbA1c level of between 5.7 and 6.4% is an indicator of pre-diabetes.

Streck, Inc. (Omaha, NE, USA), an industry leader in the development and manufacturing of products for clinical and research laboratories, has released its A1c-Cellular control product, the only HbA1c control on the market with intact red blood cells.

The A1c-Cellular control is convenient to use, as it does not require reconstitution. It controls the entire HbA1c assay procedure, including the lysing of the red blood cells—a step omitted with other controls. This important feature ensures the entire system—instrument and reagents—is working properly and providing accurate patient results.

The A1c-Cellular control has been calibrated and certified for use on many of the major clinical autoanalyzers including: the Abbott (North Chicago, IL, USA) ARCHITECT c Systems; the Beckman Coulter (Indianapolis, IN, USA) UniCel DxC 600/800; the Bio-Rad (Hercules, CA, USA) D-10/Variant II and Variant II Turbo; the Roche (Pleasanton, CA, USA) cobas INTEGRA/6000/c311; the Siemens (Malvern, PA, USA) Dimension Series; and the Tosoh (Grove City, OH, USA) A1c analyzer, HLC-723G7.

A1c-Cellular control is available in two clinically significant levels: 4%–7% HbA1c (Level 1) and 9%–13% HbA1c (Level 2).

Related Links:

Streck, Inc. 


Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
HLX
Anti-Cyclic Citrullinated Peptide Test
GPP-100 Anti-CCP Kit
New
Gold Member
Magnetic Bead Separation Modules
MAG and HEATMAG
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get complete access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Molecular Diagnostics

view channel
Image: The cobas Malaria test is the first FDA-approved molecular test to screen U.S. blood donors for malaria (Photo courtesy of Roche)

First FDA-Approved Molecular Test to Screen Blood Donors for Malaria Could Improve Patient Safety

Malaria, a serious illness that often leads to death, is spread by a specific mosquito species that infect humans with a parasite. Other transmission modes include blood transfusions, organ transplants,... Read more

Hematology

view channel
Image: The low-cost portable device rapidly identifies chemotherapy patients at risk of sepsis (Photo courtesy of 52North Health)

POC Finger-Prick Blood Test Determines Risk of Neutropenic Sepsis in Patients Undergoing Chemotherapy

Neutropenia, a decrease in neutrophils (a type of white blood cell crucial for fighting infections), is a frequent side effect of certain cancer treatments. This condition elevates the risk of infections,... Read more

Pathology

view channel
Image: The medical office procedure detects the key biomarker in Parkinson’s and related neurodegenerative diseases (Photo courtesy of BIDMC)

Simple Skin Biopsy Test Detects Parkinson’s and Related Neurodegenerative Diseases

Parkinson's disease and a group of related neurodegenerative disorders known as synucleinopathies impact millions globally. These conditions, including Parkinson’s disease (PD), dementia with Lewy bodies... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.