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Pathology

Image: The CFX96 real-time PCR detection system (Photo courtesy of Bio-Rad).

Circulating Cell-Free DNA Predicts Gastric Cancer Patients Prognosis

Gastric cancer is the second most common cancer and the fourth leading cause of cancer death and the most significant prognostic indicator is TNM Classification of Malignant Tumors (TNM) staging. More...
21 Dec 2016
Image: An immunofluorescence of Escherichia coli K99 pili protein in human brains (Photo courtesy of University of California at Davis).

Gram-Negative Bacterial Molecules Associated with Alzheimer Disease Pathology

Scientists have known for some time that infections can increase the risk of Alzheimer's. However, now for the first time it has been found increased levels of Gram-negative bacteria antigens in Alzheimer's disease brains and bacterial molecules associated with the disease pathology. More...
15 Dec 2016
Image: A Petri dish culture plate that contains Cycloserine Cefoxitin Fructose Agar (CCFA), which had been inoculated with a Clostridium difficile bacterial culture. The plate had been illuminated using long-wave UV irradiation, hence, the bacterial colonies emitted a yellow-green, or chartreuse fluorescent glow (Photo courtesy of James Gathany).

Antibiotics Prevent Common Hospital-Acquired Infection in Transplant Patients

Clostridium difficile infection, more commonly known as C. diff, causes diarrhea and can lead to severe inflammation of the bowel and these infections can be not only extremely uncomfortable, but can lead to other severe medical complications. More...
14 Dec 2016
Image: A histopathology of necrotizing fasciitis of the skin showing amorphous grey or pink material and neutrophils (Photo courtesy of Nephron).

Prognostic Factors Evaluated for Synchronous Multifocal Necrotizing Fasciitis

Necrotizing fasciitis is an infection caused by bacteria and it can destroy skin, fat, and the tissue covering the muscles within a very short time. The disease sometimes is called flesh-eating bacteria and when it occurs on the genitals, it is called Fournier gangrene. More...
14 Dec 2016
Image: A colorized scanning electron micrograph (SEM) of two lung cancer cells (Photo courtesy of Anne Weston/Cancer Research UK).

Blood Test Could Predict Best Treatment for Lung Cancer

A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment. In most patients with SCLC, a metastatic, aggressive disease, the condition is initially chemosensitive, but then relapses with acquired chemoresistance. More...
09 Dec 2016
Image: p15 expressed in nevi is a key factor mediating BRAF-induced growth arrest. A, p15 expression in a benign intradermal nevus and B, antibody control C, co-immunofluorescence of p15 and Melan-A in a representative intradermal benign nevus. D, nevus melanocytes express p15, whereas non- nevus melanocytes (white arrows) are p15-negative (Photo courtesy of University of Pennsylvania).

Specific Gene Expression Differentiates Moles from Melanoma

Most melanomas are driven by mutations that spur out-of-control cell replication, while nevi which are moles composed of non-cancerous cells at the skin surface, that harbor the same mutations do not grow wildly. More...
08 Dec 2016
Image: The LSM 780 laser scanning confocal microscope (Photo courtesy of Zeiss).

Diagnostic Tool Designed for Familial Mediterranean Fever

A tool has been developed to diagnose Familial Mediterranean Fever (FMF) which is particularly common among populations originating from around Mediterranean Sea and this genetic disease is characterized by inflammation, fever and severe pain. More...
08 Dec 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.

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