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Image: The study authors indicate that genetic testing could identify IBD patients at risk of severe disease, allowing closer monitoring and earlier use of advanced therapies (Photo courtesy of Shutterstock)

Genetic Testing Identifies High-Risk Patients with Inflammatory Bowel Disease

Researchers identify a genetic marker of severe IBD, enabling risk stratification and earlier advanced therapy. Read more
17 Jun 2026 | Molecular Diagnostics
Image

QIAGEN Enhances QIAcuity Platform with Gene Expression and Multiplexing Tools

New dPCR tools add gene expression assays, 12-plex RNA detection, and automated reporting to standardize biopharma workflows. Read more
17 Jun 2026 | Industry
Image: Graphical Abstract (Emery, J. K., V. Nemidkanam, N. Colon, et al. Journal of Extracellular Vesicles (2026). https://doi.org/10.1002/jev2.70286)

Extracellular Vesicle Biomarker May Enable Noninvasive Monitoring of H. pylori

Researchers identify H. pylori EVs that deliver a cancer-linked protein into stomach cells, supporting new biomarker and therapy strategies. Read more
17 Jun 2026 | Microbiology
Image: The researchers note that ancestry-linked genetic markers can help identify targetable mutations and guide treatments associated with better survival outcomes (Image credit: 123RF)

Ancestry-Informed Genomics Advances Precision Cancer Prognosis

New data show combining genetic ancestry with tumor sequencing improves survival prediction across cancers. Read more
17 Jun 2026 | Molecular Diagnostics
Image: A new study shows that a blood test estimating the biological age of 11 organ systems can forecast organ-specific disease and mortality risk years in advance (Image Credit: Shutterstock)

New Blood Test Predicts Organ-Specific Disease and Mortality Years in Advance

A new blood proteomic test estimates biological ages of 11 organs and forecasts organ-specific disease and mortality years ahead. Read more
16 Jun 2026 | Molecular Diagnostics
Image: DCISionRT integrates molecular biomarkers with clinicopathologic factors to assess individualized recurrence risk and predict radiation therapy benefit after breast-conserving surgery (Photo courtesy of PreludeDx)

Genomic Assay Predicts Recurrence Risk in Noninvasive Breast Cancer

A new genomic test integrates biomarkers and clinical data to stratify DCIS recurrence risk and predict radiation benefit. Read more
16 Jun 2026 | Molecular Diagnostics
Image: Healthy and cancerous regions in a H&Eble results (Photo courtesy of KAUST)

Stain-Free Imaging Platform Matches Standard Cancer Pathology

A stain-free imaging system achieves 99% diagnostic concordance, cuts prep time up to 50%, and standardizes data. Read more
16 Jun 2026 | Pathology
Image: The study results point to mutations in the COPA gene as an important driver of cancer progression in small intestinal adenomas (Image credit: Professor Shigeki Sekine and Professor Toshiro Sato, Keio University School of Medicine, Japan)

New Findings Clarify Molecular Drivers of Rare Small Intestinal Cancer

New findings show that recurrent COPA mutations may drive cancer-related signaling in small intestinal tumors. Read more
16 Jun 2026 | BioResearch
Image: The partnership aims to broaden access to ultrasensitive blood-based testing for multiple myeloma and other hematologic malignancies (Image credit: 123RF)

Partnership Expands Ultrasensitive Blood-Based Diagnostics for Hematologic Malignancies

A new service integrating flow cytometry with single-cell genomics enables ultrasensitive blood detection of rare tumor clones. Read more
16 Jun 2026 | Industry
Image: Professor Alexander Hoischen using long read genome sequencing (Photo courtesy of Radboudumc)

Long-Read DNA Test Improves Diagnosis of Rare Genetic Diseases

A long-read genome sequencing test increases rare disease diagnoses and replaces 15 other tests. Read more
15 Jun 2026 | Molecular Diagnostics
Image: The VENTANA PTEN (SP218) RxDx Assay is a qualitative IHC assay for assessing PTEN protein in prostate adenocarcinoma, with staining performed using the OptiView DAB IHC Detection Kit on a BenchMark ULTRA instrument (Photo courtesy of Roche)

New Companion Diagnostic Expands Precision Medicine in Prostate Cancer

Roche’s VENTANA PTEN (SP218) RxDx Assay is the first FDA-approved IHC companion diagnostic for detecting PTEN protein loss in prostate adenocarcinoma. Read more
15 Jun 2026 | Pathology
Image: The study evaluated SARS-CoV-2 antibody profiling, specifically titers against the spike (S) and nucleocapsid (N) proteins, as a tool to characterize long COVID (Image credit: iStock)

Antibody Profiles Provide Clues to Long COVID Severity and Symptoms

New findings show SARS‑CoV‑2 spike/nucleocapsid antibodies help stratify long COVID. Read more
15 Jun 2026 | Immunology
Image: Following FDA clearance, providers can prescribe the kit, enabling labs to process home-collected urine specimens on cobas automated platforms (Photo courtesy of Orasure Technologies)

At-Home Urine Collection Kit Enables High-Throughput STI Screening

OraSure Technologies’ Colli-Pee Dx Urine Collection Kit has received U.S. FDA clearance for use with Roche assays on the cobas molecular diagnostic system Read more
15 Jun 2026 | Molecular Diagnostics
Image: Using deep sequencing of cell-free fetal DNA from maternal blood and advanced computational analysis, the method reconstructs fetal variants across the exome (Image credit: Adobe Stock)

Noninvasive Sequencing Test Approaches Invasive Genome Sequencing for Prenatal Screening

A new noninvasive fetal sequencing method detects more than 95% of clinically relevant variants found by invasive genome sequencing. Read more
15 Jun 2026 | Molecular Diagnostics

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Clinical Chemistry

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Plasma Vitamin C Levels Associated with Brain Structure and Connectivity in Agin...
Mass Spectrometry Detects Tumor Metabolites for Cancer Monitoring
Image: A simple oral swab detected blood-matched inflammatory signals in children with primary ciliary dyskinesia, offering a needle-free way to monitor inflammation during routine care (Image credit: Shutterstock)

Simple Oral Swab Monitors Persistent Inflammation in Primary Ciliary Dyskinesia

Primary ciliary dyskinesia is a rare lung disease that affects about one in 7,500 to 10,000 live births worldwide. Symptoms can begin in the newborn period and progress to recurrent respiratory infections... Read more

Molecular Diagnostics

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Ultrasensitive HPV Blood Test Predicts Early Recurrence in Head and Neck Cancer
New Library Normalization and Amplification Tools Support Oncology Sequencing
Statistical Method Improves Detection of Low-Level Cancer DNA in Blood Samples
Image: Guardant360 CDx is approved as a companion diagnostic for therapies in NSCLC, breast cancer, and colorectal cancer (Photo courtesy of Guardant Health)

Blood-Based Assay Detects HER2 Mutations to Guide NSCLC Treatment

Non-small cell lung cancer (NSCLC) is the most common form of lung cancer, and a subset of patients harbor HER2 (ERBB2) mutations that may be addressed with precision therapies. These HER2‑mutant tumors... Read more

Hematology

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Blood Eosinophil Count May Predict Cancer Immunotherapy Response and Toxicity
Higher Ferritin Threshold May Improve Iron Deficiency Detection in Children
Stem Cell Biomarkers May Guide Precision Treatment in Acute Myeloid Leukemia
Image: Sysmex America’s next generation XR-Series, a hematology solution designed to help busy laboratories deliver fast, reliable results while maintaining efficient workflows (Photo courtesy of Sysmex America)

Next-Generation Hematology Platform Streamlines High-Complexity Lab Workflows

Sysmex America (Chicago, IL, USA) has introduced the next generation XR-Series, centered on the XR-10 Automated Hematology Module for high-complexity laboratories. The platform builds on the widely used... Read more

Immunology

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Study Points to Autoimmune Pathway Behind Long COVID Symptoms
Metabolic Biomarker Distinguishes Latent from Active Tuberculosis and Tracks Tre...
Immune Enzyme Linked to Treatment-Resistant Inflammatory Bowel Disease
Image: (A) Schematic illustration of the X-aptamer protein SELEX process for isolating aptamers. (B) Schematic illustration of the ultrasensitive detection of the SARS-CoV-2 N protein via the MD ELAAA platform. (Shu Zhou, Yuxi Xu, Huan Liao, et al. Genomics (2026). DOI: 10.1016/j.gendis.2025.101943)

Aptamer-Based Biosensor Enables Mutation-Resilient SARS-CoV-2 Detection

Rapid evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can undermine existing molecular diagnostics, especially when assays target small viral components. Double-antibody sandwich... Read more

Microbiology

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New Protein Targets Support Diagnostics for Louse-Borne Relapsing Fever
TORCH Infection Trends Point to Need for Tailored Screening in Pregnancy
New Culture Medium Speeds C. difficile Resistance Detection and Reduces Costs
Image: The study compares rapid molecular CPE diagnostics, which can return results in about one hour, with culture-based screening, which typically takes about 48 hours (Image credit: Adobe Stock)

Rapid Molecular Screening Aims to Accelerate Hospital Infection Control for CPE

Drug-resistant infections remain a critical patient-safety threat in hospitals, with carbapenemase-producing Enterobacterales (CPE) among the most urgent concerns. In England, reports of acquired carbapenemase... Read more

Pathology

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AI Tool Speeds Brain Tumor Classification from Routine Histology Slides
IHC Companion Diagnostic Standardizes Mismatch Repair Testing for Cancer Immunot...
AI Pathology Tool Predicts Meningioma Recurrence from Routine Slides
Image: Overview of the uncertainty-aware lensfree computational pathology platform for automated HER2 assessment. A compact lensfree holographic imaging system captures diffraction patterns from immunohistochemically stained breast tissue samples, which are computationally reconstructed and analyzed using deep neural networks with Bayesian uncertainty quantification. (Photo courtesy of Ozcan Lab, UCLA)

Uncertainty-Aware AI Platform Supports Automated HER2 Assessment in Breast Cancer

Accurate assessment of human epidermal growth factor receptor 2 (HER2) is critical for breast cancer diagnosis and treatment selection, yet scoring variability and infrastructure requirements can complicate... Read more

Technology

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Agentic AI Platform Supports Genomic Decision-Making in Oncology
Mailed Screening Kits Help Reduce Colorectal Cancer Screening Gaps
Algorithm Panel Aids Liver Fibrosis Assessment and Liver Cancer Surveillance
Image: Foundation Medicine will launch advanced digital solutions integrated with Roche’s navify Clinical Hub to deliver personalized insights to U.S. providers at the point of care (Photo courtesy of Roche)

AI Platform Links Biomarker Results to Cancer Clinical Trials and Guidelines

Oncology teams must manage growing volumes of genomic data, rapidly evolving clinical trial options, and frequently updated care guidelines, all within tight clinic schedules. Translating complex tumor... Read more

Industry

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Genetic Testing Program Expands Detection of Alpha-1 Antitrypsin Deficiency
Collaboration Advances ctDNA-Guided Development in Metastatic Colorectal Cancer
Diazyme Laboratories Acquires Carolina Liquid Chemistries
Image: Tempus will open source the Paige IMS, including its slide viewer, case management solution, and AI integration modules, providing a clinical-grade baseline platform for institutions worldwide (Photo courtesy of Tempus)

Open-Source Consortium Aims to Standardize Digital Pathology Workflows

Digital pathology is expanding rapidly as laboratories adopt whole-slide imaging and computational tools to meet growing diagnostic and biomarker-testing demand. However, fragmented software infrastructure... Read more

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