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AI-Powered Blood Test Enables Detection, Analysis and Profiling of Cancer Tumors

Biosensing Technology Breakthrough Paves Way for New Methods of Early Disease Detection

1 Hour Direct-From-Blood Test Detects 95% Of Pathogens Associated with Bloodstream Infections

Personalized CBC Testing Could Help Diagnose Early-Stage Diseases in Healthy Individuals

Optimized Pooled Testing Approach Could Transform Public Health Screening for Infectious Diseases

World-First Urine Test Uses ‘Zombie’ Cell Proteins for Early Lung Cancer Detection

First AI-Powered Blood Test Identifies Patients in Earliest Stage of Breast Cancer

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First-Of-Its-Kind Smartphone Technology Noninvasively Measures Blood Hemoglobin Levels at POC

New Blood Test Platform Simultaneously Measures Over 100 Biomarkers of Alzheimer's Disease

POC Saliva Testing Device Predicts Heart Failure in 15 Minutes

EDAN Instruments Highlights Range of Lab Analyzers, ECG Devices and Ultrasound Systems

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Revolutionary Robotic Surgery Combines Dual-System Technologies for Groundbreaking Prostate Procedure

Gel-Based Stretchable Triboelectric Nanogenerators to Revolutionize Wearable Technology

First Of Its Kind Wearable Sticker Accurately Monitors and Detects Changes in Breathing

Robotic-Assisted and AR Spine Surgery Enable Equally High Degree of Precision and Accuracy, Finds Study

Magnetically Driven Robotic Microscrews for Fallopian Tube Blockages to Revolutionize Infertility Treatment

Blood Test for Early Alzheimer’s Detection Could Help Slow Disease Progression

Image: This joint effort will use samples from KU ADRC research to validate a blood test developed by BYU (Photo courtesy of KU ADRC)

Researchers are preparing to conduct a validation study of a blood test for the early detection of neurodegeneration in Alzheimer’s disease.
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20 Dec 2024

New Lens Method Analyzes Tears for Early Disease Detection

20 Dec 2024

Cost-Effective Blood Test Could Detect Early Brain Changes Leading to Dementia

19 Dec 2024

New Microscopy Technique Enables Rapid Tumor Analysis by Surgeons in OR

19 Dec 2024

AI Model Excels at Analyzing Diverse Cancer Types and Unseen IHC Data

18 Dec 2024

New Test for Early Osteoarthritis Diagnosis to Improve Clinical Decision-Making

18 Dec 2024

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Worldwide Initiative Aims to Develop Globally Generalizable Blood-Based Tests for Alzheimer’s Disease

The Davos Alzheimer’s Collaborative (DAC, Geneva, Switzerland), a pioneering worldwide initiative seeking to cure Alzheimer’s disease and improve brain health, will work with Johnson & Johnson’s Janssen Research & Development (Raritan, NJ, USA) and Beckman Coulter Diagnostics (Brea, CA, USA), two leading pharmaceutical and diagnostics companies, to advance the assay validation of blood-based biomarkers (BBMs) for Alzheimer’s disease for global use in diverse populations. Read more
20 Dec 2024

Hologic Enters into Agreement with CDC for H5N1 Bird Flu Test Development

H5N1 avian influenza, commonly referred to as bird flu, is still spreading among wild birds globally and has led to outbreaks in poultry and dairy cows in the U. Read more
19 Dec 2024

Quanterix Acquires Magnetic Bead Tech Firm Emission

Quanterix Corporation (Billerica, MA, USA), a company fueling scientific discovery and breakthrough diagnostics through ultrasensitive biomarker detection, has acquired EMISSION iNC (Georgetown, TX, USA), expanding its technology capabilities through vertical integration of proprietary bead technology. Read more
18 Dec 2024

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In Other News

Image: Site-selective immobilization of different bioreceptors on individual field-effect transistors, achieved through the use of thermal scanning probe lithography (Photo courtesy of NYU Tandon)

FET-Based Sensors Pave Way for Portable Diagnostic Devices Capable of Detecting Multiple Diseases

In a world facing a wide range of health challenges, from rapidly spreading viruses to chronic diseases and drug-resistant bacteria, the demand for fast, reliable, and user-friendly home diagnostic tests is more critical than ever. Read more
17 Dec 2024 | Technology

Image: The new paper-based biosensor system uses bacterial spores that germinate in response to glucose in potassium-rich bodily fluids, such as sweat (Photo courtesy of Binghamton University)

Paper-Based Biosensor System to Detect Glucose Using Sweat Could Revolutionize Diabetes Management

Millions of individuals with diabetes monitor their glucose levels daily using finger-stick devices that draw and analyze blood. Read more
17 Dec 2024 | Technology

Image: An AI-powered blood test is the first to spot the earliest sign of breast cancer (Photo courtesy of 123RF)

First AI-Powered Blood Test Identifies Patients in Earliest Stage of Breast Cancer

Standard breast cancer tests typically include a physical exam, X-ray or ultrasound scans, and a biopsy to analyze tissue samples. Read more
16 Dec 2024 | Technology

Image: The machine-learning model analyzes photos of placentas to detect health risks (Photo courtesy of Patterns, DOI: 10.1016/j.patter.2024.101097)

AI Tool Analyzes Placentas at Birth to Accurately Detect Health Risks

The placenta is crucial to the health of both the pregnant individual and the baby during pregnancy, but it is often not examined thoroughly after birth, especially in areas with limited medical resources. Read more
16 Dec 2024 | Pathology

Image: The new study highlights efficiency in detecting infectious diseases (Photo courtesy of Adobe Stock)

Optimized Pooled Testing Approach Could Transform Public Health Screening for Infectious Diseases

Traditional individual testing methods can be resource-intensive, particularly when it comes to large-scale screenings. Read more
13 Dec 2024 | Pathology

Image: Personalized blood count could lead to early intervention for common diseases (Photo courtesy of 123RF)

Personalized CBC Testing Could Help Diagnose Early-Stage Diseases in Healthy Individuals

A complete blood count (CBC) screening is a standard examination most physicians request for healthy adults. Read more
13 Dec 2024 | Hematology

Image: The AR-ctDETECT test detects and analyzes small fragments of tumor-derived DNA in the blood of patients with advanced, metastatic prostate cancer (Photo courtesy of 123RF)

New Blood Test Predicts Prognosis for Advanced Prostate Cancer Patients

A new study has revealed that a DNA sequencing test for advanced prostate cancer patients can differentiate between those with poor and favorable prognoses. Read more
12 Dec 2024 | Molecular Diagnostics

Image: The BIOFIRE® FILMARRAY® Tropical Fever Panel has received U.S. FDA Special 510(k) clearance (Photo courtesy of bioMérieux)

Syndromic PCR Test Rapidly and Accurately Identifies Pathogens in Patients with Tropical Fever Infections

Tropical fevers refer to infections that are common in, or unique to, tropical and subtropical regions. Read more
12 Dec 2024 | Microbiology

Image: researchers combined DNA origami structures with solid-state nanopores to enhance the detection of proteins (Photo courtesy of 123RF)

Biosensing Technology Breakthrough Paves Way for New Methods of Early Disease Detection

Nanopores are tiny openings that can detect individual molecules as they pass through, making them ideal for analyzing biomolecules like DNA and proteins. Read more
11 Dec 2024 | Clinical Chem.

Image: The UllCORE BSI Test and UllCore system detect 95% of pathogens associated with BSIs directly from blood in 1 hour (Photo courtesy of deepull)

1 Hour Direct-From-Blood Test Detects 95% Of Pathogens Associated with Bloodstream Infections

Early detection is crucial for treating a variety of infections, particularly sepsis. Sepsis is responsible for one in three hospital deaths in the U. Read more
11 Dec 2024 | Microbiology

Image: The new method will help guide cancer treatment using blood samples (Photo courtesy of 123RF)

AI-Powered Blood Test Enables Detection, Analysis and Profiling of Cancer Tumors

Mutational signatures are changes in DNA patterns caused by cancer’s effects on cells in the body. These signatures can provide valuable insights into the cancer, such as the potential causes behind its development and which therapies may be most effective. Read more
10 Dec 2024 | Molecular Diagnostics

Image: World-first urine test for lung cancer picks out ‘zombie’ cells (Photo courtesy of Shutterstock)

World-First Urine Test Uses ‘Zombie’ Cell Proteins for Early Lung Cancer Detection

Lung cancer has a poor prognosis for many patients because symptoms often do not appear until the disease has spread to other parts of the body or throughout the lungs. Read more
10 Dec 2024 | Molecular Diagnostics

Image: A potential epigenetic biomarker has been found for preeclampsia in pregnancy (Photo courtesy of 123RF)

Cheek Swab Test Could Detect Risk of Preterm Birth

Preeclampsia is a serious condition that can be life-threatening and often results in preterm births, which are defined as births occurring before 37 weeks of gestation. Read more
09 Dec 2024 | Molecular Diagnostics

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Clinical Chemistry

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Image: Rapid and non-invasive analysis of paracetamol overdose using paper arrow-mass spectrometry (Photo courtesy of Dr Simon Maher/University of Liverpool)

New Saliva Test Rapidly Identifies Paracetamol Overdose

Paracetamol is the most widely used medication worldwide, and its easy availability contributes to its frequent misuse and overdose. Overdosing on paracetamol can lead to liver toxicity, requiring hospitalization.... Read more

Image: The new saliva-based test for heart failure measures two biomarkers in about 15 minutes (Photo courtesy of Trey Pittman)

POC Saliva Testing Device Predicts Heart Failure in 15 Minutes

Heart failure is a serious condition where the heart muscle is unable to pump sufficient oxygen-rich blood throughout the body. It ranks as a major cause of death globally and is particularly fatal for... Read more

Image: PhD student and first author Tarek Eissa has analyzed thousands of molecular fingerprints (Photo courtesy of Thorsten Naeser / MPQ / Attoworld)

Screening Tool Detects Multiple Health Conditions from Single Blood Drop

Infrared spectroscopy, a method using infrared light to study the molecular composition of substances, has been a foundational tool in chemistry for decades, functioning similarly to a molecular fingerprinting... Read more

Image: The new DxC 500i Clinical Analyzer is an integrated clinical chemistry and immunoassay analyzer (Photo courtesy of Beckman Coulter Diagnostics)

Integrated Chemistry and Immunoassay Analyzer with Extensive Assay Menu Offers Flexibility, Scalability and Data Commutability

As global healthcare systems increasingly shift towards networked laboratory operational models to enhance efficiency and patient access, there is a greater need for innovative solutions tailored to the... Read more

Molecular Diagnostics

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$Image: Xpert MTB/RIF Ultra is the first test for TB diagnosis and antibiotic susceptibility testing to meet WHO\'s prequalification standards (Photo courtesy of Cepheid)$

First TB Molecular Diagnostic Test Granted WHO Prequalification

Tuberculosis (TB) is one of the most deadly infectious diseases globally, responsible for over a million deaths each year and imposing significant socioeconomic challenges, particularly in low- and middle-income... Read more

Image: The study found previously undetected cancers in pregnant women with abnormal prenatal cfDNA test results (Photo courtesy of NIH)

Abnormal Prenatal Blood Test Results Could Indicate Hidden Maternal Cancers

Researchers have discovered previously undiagnosed cancers in 48.6% of pregnant individuals who received abnormal results from prenatal cell-free DNA (cfDNA) testing, which is typically used to screen... Read more

Image: The automated multiplex diagnostics system developed by HKBU Professor Terence Lau detects 42 respiratory pathogens in less than 1.5 hours (Photo courtesy of HKBU)

Automated Multiplex Diagnostics System Enables Rapid Detection of Multiple Pathogens

Each year, the World Health Organization (WHO) releases its Compendium of Innovative Health Technologies for Low-resource Settings, which highlights commercially available solutions and prototypes designed... Read more

Image: A sarcomere, or part of a cardiomyocyte that helps heart cells beat, retains its structure after treatment with indisulam and doxorubicin (Photo courtesy of Joseph Wu lab/Stanford Medicine)

New Screening Technique Identifies Genes Behind Heart Cell Damage from Chemotherapy

Doxorubicin is a potent chemotherapy drug that effectively targets cancer cells, but it also disrupts heart cells, causing them to beat irregularly, organize incorrectly, or even die. When used in high... Read more

Hematology

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Image: RHD screening just got easier with single exon NIPT testing (Photo courtesy of Devyser)

Non-Invasive Test Solution Determines Fetal RhD Status from Maternal Plasma

RhD (rhesus D) is a blood group type that can trigger immune responses. Individuals who lack RhD on their red blood cells are classified as RhD-negative. These individuals may produce antibodies against... Read more

First-Of-Its-Kind Smartphone Technology Noninvasively Measures Blood Hemoglobin Levels at POC

Blood hemoglobin tests are among the most frequently conducted blood tests, as hemoglobin levels can provide vital insights into various health conditions. However, traditional tests are often underutilized... Read more

Image: QScout CBC will give a complete blood count in 2 minutes from fingerstick or venous blood (Photo courtesy of Ad Astra Diagnostics)

Next Gen CBC and Sepsis Diagnostic System Targets Faster, Earlier, Easier Results

Every hour is critical in protecting patients from infections, yet there are currently limited tools to assist in early diagnosis before patients reach a hospital. The complete blood count (CBC) is a common... Read more

Image: The discovery of a new blood group has solved a 50- year-old mystery (Photo courtesy of 123RF)

Newly Discovered Blood Group System to Help Identify and Treat Rare Patients

The AnWj blood group antigen, a surface marker discovered in 1972, has remained a mystery regarding its genetic origin—until now. The most common cause of being AnWj-negative is linked to hematological... Read more

Immunology

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Image: Concept for the device. Memory B cells able to bind influenza virus remain stuck to channels despite shear forces (Photo courtesy of Steven George/UC Davis)

Microfluidic Chip-Based Device to Measure Viral Immunity

Each winter, a new variant of influenza emerges, posing a challenge for immunity. People who have previously been infected or vaccinated against the flu may have some level of protection, but how well... Read more

Simple Blood Test Could Detect Drug Resistance in Ovarian Cancer Patients

Every year, hundreds of thousands of women across the world are diagnosed with ovarian and breast cancer. PARP inhibitors (PARPi) therapy has been a major advancement in treating these cancers, particularly... Read more

Advanced Imaging Method Maps Immune Cell Connections to Predict Cancer Patients Survival

A growing tumor is influenced not only by the tumor cells themselves but also by the surrounding tissue, which alters its biology. Immune cells communicate by transferring vital signaling proteins to their... Read more

Image: The new method assesses which patients with metastatic triple-negative breast cancer could benefit from immunotherapy (Photo courtesy of Theinmozhi Arulraj and Aleksander Popel)

Computational Tool Predicts Immunotherapy Outcomes for Metastatic Breast Cancer Patients

Immunotherapy aims to enhance the body’s immune response to target cancer cells, but not all patients experience a positive reaction to such treatments. Identifying which patients will benefit from immunotherapy... Read more

Microbiology

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New Hands-Free Rapid Test Detects Bacteria in Fluids

Bacteriophages, the most abundant form of life on Earth, are specialized to target and destroy specific types of bacteria. Their natural ability to fight bacteria has long been harnessed to treat infections.... Read more

Image: HNL Dimer can be a novel and potentially useful clinical tool in antibiotic stewardship in sepsis (Photo courtesy of Shutterstock)

Unique Blood Biomarker Shown to Effectively Monitor Sepsis Treatment

Sepsis remains a growing problem across the world, linked to high rates of mortality and morbidity. Timely and accurate diagnosis, along with effective supportive therapy, is essential in reducing sepsis-related... Read more

Image: The InfectoSynovia test has the potential to revolutionize the diagnosis of periprosthetic joint infection (Photo courtesy of 123RF)

High-Accuracy Bedside Test to Diagnose Periprosthetic Joint Infection in Five Minutes

Periprosthetic joint infection (PJI) represents a significant global issue that is worsening as the number of joint replacements increases due to aging populations. In the United States alone, the anticipated... Read more

Image: Researchers have developed a method to quickly identify the most appropriate treatments for bacterial infections (Photo courtesy of Shutterstock)

Innovative Diagnostic Approach for Bacterial Infections to Enable Faster and Effective Treatment

For patients with bacterial infections, timely treatment with the appropriate antibiotics significantly improves their chances of recovery. Current methods for identifying which antibiotics will be effective... Read more

Pathology

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Image: The breakthrough by Dr. Sabine Mai and her team enables early risk-stratification of smoldering multiple myeloma (Photo courtesy of University of Manitoba)

Breakthrough Method to Enable Early Risk Stratification of Deadly Blood Cancer

Multiple myeloma is an incurable blood cancer, with patients typically surviving an average of eight years after diagnosis. Those with smoldering multiple myeloma experience no symptoms until the disease... Read more

Image: HistoTME reads routinely stained histopathology images of tumor samples (Photo courtesy of Adobe Stock)

AI-Powered Immuno-Oncology Tool Predicts Lung Cancer Treatment Outcomes

Immune checkpoint inhibitors (ICI) are used to treat non-small cell lung cancer (NSCLC) by enhancing the immune system's ability to fight cancer. However, identifying which patients will benefit most from... Read more

Image: The overall architecture, input and output of CelloType (Photo courtesy of Nature Methods: DOI: 10.1038/s41592-024-02513-1)

New AI Technology Outperforms Traditional Methods in Biomedical Image Segmentation

Spatial omics is an emerging field that integrates molecular profiling techniques like genomics, transcriptomics, and proteomics with spatial information, enabling researchers to pinpoint the location... Read more

Image: Researchers have used an AI model to automate cancer pathology reports (Photo courtesy of Shutterstock)

AI Method Measures Cancer Severity Using Pathology Reports

Researchers often rely on tumor registries, which are databases managed by hospitals and government agencies, to screen cancer patients for clinical trials. These registries require specialized staff to... Read more

Technology

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Optical Biosensor Rapidly Detects Monkeypox Virus at Point of Care

A new variant of human mpox has caused a mortality rate of approximately 5% among those infected in the Democratic Republic of the Congo since 2023, with many of the victims being children.... Read more

Image: Schematic diagram of nanomaterial-based anti-epileptic drug concentration diagnostic technology (Photo courtesy of KRISS)

Nanomaterial-Based Diagnostic Technology Accurately Monitors Drug Therapy in Epilepsy Patients

Many patients with epilepsy take anti-epileptic drugs to control frequent seizures in their daily lives. To optimize treatment and avoid side effects from overdosing, it is crucial for patients to regularly... Read more

New Noninvasive Methods Detect Lead Exposure Faster, Easier and More Accurately at POC

Exposure to lead can negatively affect health in multiple ways, leading to damage in the brain and central nervous system, delays in development and growth, learning and behavioral issues, problems with... Read more

Image: The Cytophone clinical prototype (Photo courtesy of Nat. Commun.; Yadem, A.C., Armstrong, J.N., Sarimollaoglu, M. et al.)

Noninvasive Test Detects Malaria Without Blood Sample

Malaria remains a significant global health issue, with approximately 250 million cases and over 600,000 deaths reported annually. Nearly half of the world's population is at risk for malaria infection,... Read more

Industry

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Image: DiaMex offers ready-to-use multimarker controls for common systems (Photo courtesy of DiaMex)

LGC Acquires German Quality Controls Maker DiaMex

LGC (London, UK) has made an addition to its growing global clinical diagnostics and genomics portfolio by acquiring DiaMex (Heidelberg, Germany), a manufacturer of third-party serology and molecular quality... Read more

Image: The Simple Plex Human Phospho Tau 217 ALZpath assay runs on the Ella automated immunoassay platform (Photo courtesy of Bio-Techne)

Bio-Techne and ALZpath Partner to Advance Neurodegenerative Disease Research and Treatment

Bio-Techne Corporation (Minneapolis, MN, USA) and ALZpath, Inc. (Carlsbad, CA, USA) have entered into a strategic partnership to accelerate breakthroughs in neurodegenerative disease research and treatment,... Read more

Image: Together, the companies will deliver enhanced solutions across infectious disease and oncology diagnostics (Photo courtesy of SensID)

Microbiologics Acquires Diagnostic Quality Controls Manufacturer SensID

Microbiologics (St. Cloud, MN, USA), a biotechnology company specializing in infectious disease reference materials and contract research services, has acquired SensID (Rostock, Germany), a manufacturer... Read more

Image: The NGAL Test quantifies NGAL levels in human urine, EDTA and heparin plasma (Photo courtesy of BioPorto)

Beckman Coulter Partners with BioPorto for Global Distribution of Acute Kidney Injury NGAL Tests

Acute kidney injury (AKI) is a sudden episode of kidney failure or damage that can occur within a few hours or days. This condition leads to the accumulation of waste products in the blood and disrupts... Read more

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