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Image: The findings were based on patients from the ADAURA clinical trial of the targeted therapy osimertinib for patients with NSCLC with EGFR-activated mutations (Photo courtesy of YSM Multimedia Team)

Post-Treatment Blood Test Could Inform Future Cancer Therapy Decisions

In the ongoing advancement of personalized medicine, a new study has provided evidence supporting the use of a tool that detects cancer-derived molecules in the blood of lung cancer patients years after their treatment. Read more
18 Mar 2025 | Immunology
Image: The generative AI tool can interpret millions of cells in human tissues in hours (Photo courtesy of Wellcome Sanger Institute)

First-Of-Its-Kind AI Tool Visualizes Cell’s ‘Social Network’ To Treat Cancer

Every cell in the human body is engaged in constant communication with its environment and operates within a broader network of interactions. Read more
18 Mar 2025 | Pathology
Image: Carbon nanotubes with different chirality or “twist” have different optical properties (Photo courtesy of Mikael Nyberg/University of Turku)

Carbon Nanotubes Help Build Highly Accurate Sensors for Continuous Health Monitoring

Current sensors can measure various health indicators, such as blood glucose levels, in the body. However, there is a need to develop more accurate and sensitive sensor materials that can detect lower concentrations of certain substances. Read more
17 Mar 2025 | Clinical Chem.
Image: A small, complex item printed using the 3D printing innovation (Photo courtesy of John O’Malley/Purdue University)

3D Printing Breakthrough Enables Large Scale Development of Tiny Microfluidic Devices

Microfluidic devices are diagnostic systems capable of analyzing small volumes of materials with precision and speed. Read more
17 Mar 2025 | Technology
Image: The new technology offers rapid, highly sensitive detection of multi-drug-resistant bacteria (Photo courtesy of Adobe Stock)

CRISPR-Based Diagnostic Test Detects Pathogens in Blood Without Amplification

Rapid detection of pathogens is essential for effective disease management, especially in cases of bloodstream infections. Read more
17 Mar 2025 | Molecular Diagnostics
Image: The device, designed by UTEP chemistry doctoral student Ruma Paul, simplifies colorectal cancer detection (Photo courtesy of UTEP)

Portable Blood-Based Device Detects Colon Cancer

Colon cancer is the second leading cause of cancer-related deaths in the U.S., yet it is highly treatable when detected at an early stage. Read more
14 Mar 2025 | Molecular Diagnostics
Image: The new test offers the possibility of more personalized treatment options for medulloblastoma (Photo courtesy of Adobe Stock)

New Test Diagnoses High-Risk Childhood Brain Tumors

Medulloblastoma, which originates in the cerebellum, the rear part of the brain, is the most prevalent malignant brain tumor in children and is notoriously difficult to diagnose. Read more
14 Mar 2025 | Pathology
Image: The DNA sequencing method indentifies the bacterial causes of infections to determine the most effective antibiotics for treatment (Photo courtesy of Shutterstock)

New DNA Test Diagnoses Bacterial Infections Faster and More Accurately

Antimicrobial resistance has emerged as a significant global health threat, causing at least one million deaths annually since 1990. Read more
14 Mar 2025 | Molecular Diagnostics
Image: The next-generation microfluidics-based CTC detection technology will improve early cancer screening (Photo courtesy of CityUHK)

Innovative Bio-Detection Platform Improves Early Cancer Screening and Monitoring

Cancer remains one of the leading causes of death globally, underscoring the critical need for more advanced, efficient, and early detection methods. Read more
13 Mar 2025 | Molecular Diagnostics
Image: The test could be a game changer for people with some of the most aggressive forms of cancer (Photo courtesy of UNE)

Blood Test Could Help More Women Survive Aggressive Triple Negative Breast Cancer

Cancer research shows that over 90% of women diagnosed with breast cancer at its earliest stage survive for five years or more. Read more
12 Mar 2025 | Molecular Diagnostics
Image: Among the proteins in the cerebrospinal fluid, the researchers identified biomarkers that can accurately predict the development of ICANS (Photo courtesy of Daiki Setoyama/Kyushu University)

Cerebrospinal Fluid Test Predicts Dangerous Side Effect of Cancer Treatment

In recent years, cancer immunotherapy has emerged as a promising approach where the patient's immune system is harnessed to fight cancer. Read more
12 Mar 2025 | Immunology
Image: RT-QuIC Prion, CSF is the only definitive antemortem clinical test of its kind that doesn’t involve a brain biopsy (Photo courtesy of Mayo Clinic)

CSF Test Distinguishes Prion Disease from Other Causes of Rapidly Progressive Dementia

Rapidly progressive dementias are a category of dementia where patients experience a swift decline from the onset of symptoms to losing functional independence, typically within two years. Read more
11 Mar 2025 | Molecular Diagnostics
Image: The Results Manager System (Photo courtesy of QuidelOrtho)

Informatics Solution Elevates Laboratory Efficiency and Patient Care

QuidelOrtho Corporation (San Diego, CA, USA) has introduced the QuidelOrtho Results Manager System, a cutting-edge informatics solution designed to meet the increasing demands of modern laboratories. Read more
11 Mar 2025 | Pathology

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Clinical Chemistry

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AI-Powered Raman Spectroscopy Method Enables Rapid Drug Detection in Blood
Novel LC-MS/MS Assay Detects Low Creatinine in Sweat and Saliva
Biosensing Technology Breakthrough Paves Way for New Methods of Early Disease De...
Image: The paper-based device generates high-quality samples of dried plasma, enabling accurate measurements of HIV viral load (Photo courtesy of Charlie Mace/Tufts)

Paper-Based Device Boosts HIV Test Accuracy from Dried Blood Samples

In regions where access to clinics for routine blood tests presents financial and logistical obstacles, HIV patients are increasingly able to collect and send a drop of blood using paper-based devices... Read more

Molecular Diagnostics

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CRISPR-Based Test Diagnoses Life-Threatening Fungal Infection More Quickly
First Of Its Kind Measles Antibody Test Validated for Use with Dried Blood Spot ...
Simple Blood Test to Advance Targeted Treatments for Childhood Cancer
Image: A coronal MRI section shows a high-intensity focused ultrasound lesion in the left thalamus of the brain (Photo courtesy of UT Southwestern Medical Center)

Newly Identified Stroke Biomarkers Pave Way for Blood Tests to Quickly Diagnose Brain Injuries

Each year, nearly 800,000 individuals in the U.S. experience a stroke, which occurs when blood flow to specific areas of the brain is insufficient, causing brain cells to die due to a lack of oxygen.... Read more

Hematology

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WBC Count Could Predict Severity of COVID-19 Symptoms
New Platelet Counting Technology to Help Labs Prevent Diagnosis Errors
Streamlined Approach to Testing for Heparin-Induced Thrombocytopenia Improves Di...
Image: The technology has the unique ability to detect challenging RhD variants that are typically excluded by other commercial tests (Photo courtesy of BillionToOne)

Non-Invasive Prenatal Test for Fetal RhD Status Demonstrates 100% Accuracy

In the United States, approximately 15% of pregnant individuals are RhD-negative. However, in about 40% of these cases, the fetus is also RhD-negative, making the administration of RhoGAM unnecessary.... Read more

Immunology

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Simple Blood Test Could Help Choose Better Treatments for Patients with Recurrent...
Novel Analytical Method Tracks Progression of Autoimmune Diseases
3D Bioprinted Gastric Cancer Model Uses Patient-Derived Tissue Fragments to Predict...
Image: New insights into preterm infant immunity could inform care (Photo courtesy of 123RF)

New Test Measures Preterm Infant Immunity Using Only Two Drops of Blood

Preterm infants are particularly vulnerable due to their organs still undergoing development, which can lead to difficulties in breathing, eating, and regulating body temperature. This is especially true... Read more

Microbiology

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Rapid PCR Testing in ICU Improves Antibiotic Stewardship
Unique Genetic Signature Predicts Drug Resistance in Bacteria
Unique Barcoding System Tracks Pneumonia-Causing Bacteria as They Infect Blood S...
Image: The QIAstat-Dx Gastrointestinal Panel 2 Mini B runs on the QIAstat-Dx system (Photo courtesy of QIAGEN)

Gastrointestinal Panel Delivers Rapid Detection of Five Common Bacterial Pathogens for Outpatient Use

Acute infectious gastroenteritis results in approximately 179 million cases each year in the United States, leading to a significant number of outpatient visits and hospitalizations. To address this, a... Read more

Pathology

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New AI Tool Outperforms Previous Methods for Identifying Colorectal Cancer from ...
New Technique Predicts Aggressive Tumors Before They Metastasize
Butterfly Wings-Inspired Imaging Technique Enables Faster Cancer Diagnosis
Image: As tumor cells flow through these microfluidic chambers, they are subjected to increasing shear stress and sorted based on their adhesion strength (Photo courtesy of UC San Diego)

Microfluidic Device Assesses Stickiness of Tumor Cells to Predict Cancer Spread

Ductal carcinoma in situ (DCIS), a type of early-stage breast cancer, is often referred to as stage zero breast cancer. In many cases, it remains harmless and does not spread beyond the milk ducts where... Read more

Technology

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Study Explores Impact of POC Testing on Future of Diagnostics
Low-Cost, Fast Response Sensor Enables Early and Accurate Detection of Lung Canc...
Nanotechnology For Cervical Cancer Diagnosis Could Replace Invasive Pap Smears
Image: Deep learning-enhanced chemiluminescence vertical flow assay for high-sensitivity cardiac Troponin I testing (Photo courtesy of Ozcan Lab/UCLA)

POC Paper-Based Sensor Platform to Transform Cardiac Diagnostics

Cardiovascular diseases continue to be the leading cause of death worldwide, accounting for over 19 million fatalities annually. Early detection of myocardial infarction (MI), commonly known as a heart... Read more

Industry

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ABL Signs Know-How License and Transfer Agreement for Siemens’ Fast Track Diagno...
Becton Dickinson to Spin Out Biosciences and Diagnostic Solutions Business
New Partnership Revolutionizes Analyses of Biological Samples
Image: The Nio family of all-in-one digital PCR systems complements Bio-Rad’s existing digital PCR portfolio (Photo courtesy of Stilla)

Bio-Rad to Acquire Digital PCR Developer Stilla Technologies

Bio-Rad Laboratories (Hercules, CA, USA) has entered into a binding offer to purchase all equity interests in Stilla Technologies (Villejuif, France). The acquisition remains subject to consultation with... Read more

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