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In Other News

Image: Tempus will open source the Paige IMS, including its slide viewer, case management solution, and AI integration modules, providing a clinical-grade baseline platform for institutions worldwide (Photo courtesy of Tempus)

Open-Source Consortium Aims to Standardize Digital Pathology Workflows

A new open-source initiative now provides a clinical-grade platform and collaborative framework to advance standardization across institutions. Read more
11 Jun 2026 | Industry
Image: The TORCH complex includes pathogens that can cause mild or silent maternal infections yet lead to serious fetal complications, underscoring the need for better surveillance and prevention (photo courtesy of iStock)

TORCH Infection Trends Point to Need for Tailored Screening in Pregnancy

New data reveal persistent maternal-fetal TORCH risks in North India, supporting tailored screening and CMV-focused education. Read more
10 Jun 2026 | Microbiology
Image: The findings support genetic testing to guide screening and preventive care in young Black women with breast cancer (image credit: iStock)

Study Highlights Inherited Breast Cancer Risk Genes in Young Black Women

New data reveal BRCA1/BRCA2 variants predominate in early-onset breast cancer in Black women, supporting broader genetic testing. Read more
10 Jun 2026 | Molecular Diagnostics
Image: The study shows how targeted RNA analysis with Ambry’s ExomeReveal workflow can resolve uncertain findings and improve diagnostic clarity (Image Credit: iStock)

Targeted RNA Test Enhances Genetic Diagnosis in Exome Sequencing

A new targeted RNA analysis workflow demonstrates how uncertainty from exome testing can be reduced Read more
10 Jun 2026 | Molecular Diagnostics
Image: Findings demonstrate that AI can help classify meningiomas by extracting molecular and prognostic information from standard H&E slides already used in routine care. (Image Credit: Mikael Häggström, M.D./Wikimedia Commons, CC0 1.0)

AI Pathology Tool Predicts Meningioma Recurrence from Routine Slides

An AI approach reads routine H&E slides to classify meningiomas and predict recurrence. Read more
10 Jun 2026 | Pathology
Image: New findings connect ribosome stress biology with blood-based small RNA biomarkers, highlighting the potential of liquid biopsy for lung cancer patient stratification (Image credit: 123RF)

Blood-Based RNA Test May Predict Chemotherapy Sensitivity in Lung Cancer

New findings link ribosome quality control to liquid-biopsy small RNAs, enabling lung cancer stratification and therapy guidance. Read more
10 Jun 2026 | Molecular Diagnostics
Image: DNlite measures urinary post-translationally modified Fetuin-A (uPTM-FetA), a biomarker linked to kidney stress, inflammation, metabolic dysfunction, and progressive renal injury (Photo courtesy of Bio Preventive Medicine Corp)

Urinary Biomarker Assay Predicts Kidney Disease Progression Beyond Standard Measures

A new urinary biomarker assay may enable earlier and more precise risk stratification beyond albuminuria and eGFR. Read more
10 Jun 2026 | Clinical Chem.
Image: Alpha-1 antitrypsin deficiency (ADD) is a progressive genetic condition, a major inherited risk factor for COPD, and a cause of liver disease in children and adults (Image credit: Adobe Stock)

Genetic Testing Program Expands Detection of Alpha-1 Antitrypsin Deficiency

Grifols was named an inaugural industry sponsor of a program advancing routine, targeted Alpha-1 detection in patients with liver or lung disease. Read more
10 Jun 2026 | Industry
Image: A simple blood test could help identify which patients with head and neck cancer are most likely to benefit from immunotherapy (image credit: Adobe Stock)

Blood Test Predicts Immunotherapy Response in Head and Neck Cancer

A blood-based cfDNA fragment test predicts pre-treatment immunotherapy response in head and neck cancer, outperforming biomarkers. Read more
09 Jun 2026 | Molecular Diagnostics
Image: The modified culture medium speeds fidaxomicin resistance detection while reducing material and labor demands (image credit: Adobe Stock)

New Culture Medium Speeds C. difficile Resistance Detection and Reduces Costs

A modified culture medium speeds detection of fidaxomicin-resistant C. difficile with 100% sensitivity. Read more
09 Jun 2026 | Microbiology
Image: The fully automated solution increases vial loading by 50% and supports up to 960 vials per module, extending walk-away time (Photo courtesy of Waters Corporation)

Automated Blood Culture System Speeds Detection of Bloodstream Infections

The BD BACTEC FXI Culture System has received FDA 510(k) clearance and is now available to U.S. laboratories. Read more
09 Jun 2026 | Microbiology
Image: Roche developed a research-use PCR assay within six days of the Bundibugyo virus genome sequence being published (image credit: Adobe Stock)

New PCR Assay Supports Bundibugyo Ebola Outbreak Surveillance

A new research-use PCR test detects Bundibugyo virus to support faster outbreak response. Read more
08 Jun 2026 | Molecular Diagnostics
Image: Under the agreement, Natera will evaluate ctDNA from clinical trial samples collected in CytoDyn’s CLOVER Phase 2 study

Collaboration Advances ctDNA-Guided Development in Metastatic Colorectal Cancer

A personalized ctDNA-based MRD test assesses residual disease and response in metastatic CRC to inform leronlimab development. Read more
08 Jun 2026 | Industry
Image: The Deep Visual Spatial Transcriptomics and Proteomics (DVSTP) strategy integrates high-resolution pathology images with spatial transcriptomics and spatial proteomics to reveal the complex intra-tumor heterogeneity. DVSTP predicts molecular profiles from routine pathology slides, making spatial multi-omics more accessible. Whole–tumor 3D reconstruction reveals that SRSF6 drives immune exclusion and poor clinical outcomes (Photo courtesy of Science Bulletin)

3D Spatial Multi-Omics Maps Intra-Tumor Diversity in Colorectal Cancer

An AI–enabled, 3D spatial multi-omics strategy delineates colorectal tumor architecture and immune infiltration. Read more
06 Jun 2026 | Pathology

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Clinical Chemistry

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Simple Dual-Tau Blood Test Detects and Stages Alzheimer’s Disease
Alzheimer’s Blood Biomarkers Linked to Early Cognitive Differences Before Dement...
Urine-Based Test Shows Promise for Autism Screening in Children
Image: Graphical Abstract (Michael Scholz et al., Journal of Proteome Research (2026). DOI: 10.1021/acs.jproteome.5c01064)

Saliva-Based Test Detects Biochemical Signs of Sleep Loss

Acute sleep loss impairs cognition and motor skills, raising safety risks that resemble alcohol intoxication. Clinicians currently lack an objective biochemical test to determine when someone is dangerously... Read more

Molecular Diagnostics

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Circulating Tumor DNA Testing Guides Chemotherapy, Reduces Relapse in Colon Canc...
Researchers Uncover Distinct Chromosome Signature in Aggresive ALT Cancers
Genomic Test Guides Chemotherapy Decisions in Early-Stage Breast Cancer
Image: Graphical abstract (Pandya T, Zagorulya M, Leung MM, et al. Plasma signals of lung tumor promotion for molecular cancer prevention. Cell. 2026. doi:10.1016/j.cell.2026.05.005)

Plasma Protein Signature Predicts Lung Cancer Risk Up to Five Years Ahead

Lung cancer remains a leading cause of cancer death, and many cases are detected only after symptoms appear. Current screening programs largely target people with a history of smoking, leaving other at-risk... Read more

Hematology

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Blood Eosinophil Count May Predict Cancer Immunotherapy Response and Toxicity
Higher Ferritin Threshold May Improve Iron Deficiency Detection in Children
Stem Cell Biomarkers May Guide Precision Treatment in Acute Myeloid Leukemia
Image: Sysmex America’s next generation XR-Series, a hematology solution designed to help busy laboratories deliver fast, reliable results while maintaining efficient workflows (Photo courtesy of Sysmex America)

Next-Generation Hematology Platform Streamlines High-Complexity Lab Workflows

Sysmex America (Chicago, IL, USA) has introduced the next generation XR-Series, centered on the XR-10 Automated Hematology Module for high-complexity laboratories. The platform builds on the widely used... Read more

Immunology

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Study Points to Autoimmune Pathway Behind Long COVID Symptoms
Metabolic Biomarker Distinguishes Latent from Active Tuberculosis and Tracks Tre...
Immune Enzyme Linked to Treatment-Resistant Inflammatory Bowel Disease
Image: (A) Schematic illustration of the X-aptamer protein SELEX process for isolating aptamers. (B) Schematic illustration of the ultrasensitive detection of the SARS-CoV-2 N protein via the MD ELAAA platform. (Shu Zhou, Yuxi Xu, Huan Liao, et al. Genomics (2026). DOI: 10.1016/j.gendis.2025.101943)

Aptamer-Based Biosensor Enables Mutation-Resilient SARS-CoV-2 Detection

Rapid evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can undermine existing molecular diagnostics, especially when assays target small viral components. Double-antibody sandwich... Read more

Microbiology

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FDA-Cleared Gastrointestinal Panel Detects 24 Pathogen Targets
New AMR Assay Supports Rapid Infection Control Screening in Hospitals
Diagnostic Gaps Complicate Bundibugyo Ebola Outbreak Response in Congo
Image: Graphical Abstract (Microbiome Research Reports: DOI:10.20517/mrr.2025.96)

Gut Microbiome Signatures Help Identify Risk of IBD Progression

Inflammatory bowel disease (IBD), encompassing Crohn’s disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract with highly variable outcomes.... Read more

Pathology

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FDA Approval Expands Automated PD-L1 Testing Across Solid Tumors
AI-Powered Atlas Maps Immune Structures Linked to Cancer Outcomes
AI Tool Extracts Immune Signals from Biopsy to Inform Myeloma Therapy
Image: RMA reporter (magenta) expressed in response to neuronal activity marker (cyan) in the hippocampus (Image courtesy of Sho Watanabe/Rice University)

Blood-Based Method Tracks Gene Activity in the Living Brain

Real-time measurement of gene activity in the brain has been limited by assays requiring destructive tissue sampling. Tracking active genes could reveal how the body responds to environmental factors,... Read more

Technology

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Agentic AI Platform Supports Genomic Decision-Making in Oncology
Mailed Screening Kits Help Reduce Colorectal Cancer Screening Gaps
Algorithm Panel Aids Liver Fibrosis Assessment and Liver Cancer Surveillance
Image: Foundation Medicine will launch advanced digital solutions integrated with Roche’s navify Clinical Hub to deliver personalized insights to U.S. providers at the point of care (Photo courtesy of Roche)

AI Platform Links Biomarker Results to Cancer Clinical Trials and Guidelines

Oncology teams must manage growing volumes of genomic data, rapidly evolving clinical trial options, and frequently updated care guidelines, all within tight clinic schedules. Translating complex tumor... Read more

Industry

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Partnership Expands Access to Alzheimer’s Blood Tests in Latin America and Carib...
Global Multiplex Assays Market Driven by High-Throughput Diagnostic Demand
Global Framework Integrates Digital Pathology for Companion Diagnostic Developme...
By integrating CLC’s business, Diazyme aims to strengthen its clinical chemistry offering and broaden its diagnostic solutions for laboratories.

Diazyme Laboratories Acquires Carolina Liquid Chemistries

Diazyme Laboratories, Inc. (Poway, CA, USA), a diagnostics company developing enzyme and immunoassay-based test reagents, has acquired the business of Carolina Liquid Chemistries Corporation (CLC, Greensboro,... Read more

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