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In Other News

Image: Alpha-1 antitrypsin deficiency (ADD) is a progressive genetic condition, a major inherited risk factor for COPD, and a cause of liver disease in children and adults (Image credit: Adobe Stock)

Genetic Testing Program Expands Detection of Alpha-1 Antitrypsin Deficiency

Grifols was named an inaugural industry sponsor of a program advancing routine, targeted Alpha-1 detection in patients with liver or lung disease. Read more
10 Jun 2026 | Industry
Image: Roche developed a research-use PCR assay within six days of the Bundibugyo virus genome sequence being published (image credit: Adobe Stock)

New PCR Assay Supports Bundibugyo Ebola Outbreak Surveillance

A new research-use PCR test detects Bundibugyo virus to support faster outbreak response. Read more
08 Jun 2026 | Molecular Diagnostics
Image: Under the agreement, Natera will evaluate ctDNA from clinical trial samples collected in CytoDyn’s CLOVER Phase 2 study

Collaboration Advances ctDNA-Guided Development in Metastatic Colorectal Cancer

A personalized ctDNA-based MRD test assesses residual disease and response in metastatic CRC to inform leronlimab development. Read more
08 Jun 2026 | Industry
Image: The Deep Visual Spatial Transcriptomics and Proteomics (DVSTP) strategy integrates high-resolution pathology images with spatial transcriptomics and spatial proteomics to reveal the complex intra-tumor heterogeneity. DVSTP predicts molecular profiles from routine pathology slides, making spatial multi-omics more accessible. Whole–tumor 3D reconstruction reveals that SRSF6 drives immune exclusion and poor clinical outcomes (Photo courtesy of Science Bulletin)

3D Spatial Multi-Omics Maps Intra-Tumor Diversity in Colorectal Cancer

An AI–enabled, 3D spatial multi-omics strategy delineates colorectal tumor architecture and immune infiltration. Read more
06 Jun 2026 | Pathology
Image: Graphical abstract (Pandya T, Zagorulya M, Leung MM, et al. Plasma signals of lung tumor promotion for molecular cancer prevention. Cell. 2026. doi:10.1016/j.cell.2026.05.005)

Plasma Protein Signature Predicts Lung Cancer Risk Up to Five Years Ahead

A 14-protein blood signature predicts lung cancer risk up to five years before diagnosis, beyond smoking status. Read more
05 Jun 2026 | Molecular Diagnostics
Image: New findings show that circulating tumor DNA testing can guide postoperative chemotherapy and reduce relapse in selected patients (Image credit: Shutterstock)

Circulating Tumor DNA Testing Guides Chemotherapy, Reduces Relapse in Colon Cancer

A ctDNA blood test guides adjuvant chemotherapy in stage II colon cancer and cuts relapse risk. Read more
04 Jun 2026 | Molecular Diagnostics
Image: Graphical Abstract (Michael Scholz et al., Journal of Proteome Research (2026). DOI: 10.1021/acs.jproteome.5c01064)

Saliva-Based Test Detects Biochemical Signs of Sleep Loss

A new saliva test detects acute sleep deprivation with 94% accuracy, enabling rapid point-of-care screening. Read more
04 Jun 2026 | Clinical Chem.
Image: (A) Schematic illustration of the X-aptamer protein SELEX process for isolating aptamers. (B) Schematic illustration of the ultrasensitive detection of the SARS-CoV-2 N protein via the MD ELAAA platform. (Shu Zhou, Yuxi Xu, Huan Liao, et al. Genomics (2026). DOI: 10.1016/j.gendis.2025.101943)

Aptamer-Based Biosensor Enables Mutation-Resilient SARS-CoV-2 Detection

An aptamer-based biosensor improves SARS-CoV-2 detection, maintaining performance across mutations with sharply higher sensitivity. Read more
04 Jun 2026 | Immunology
Image: In ALT-positive cancers, researchers found that centromere-associated DNA can be inserted near telomeres at chromosome ends (Image credit: Shutterstock)

Researchers Uncover Distinct Chromosome Signature in Aggresive ALT Cancers

New findings reveal a previously unseen chromosome interaction in alternative lengthening of telomeres positive (ALT+) tumors Read more
04 Jun 2026 | Molecular Diagnostics
Image: RMA reporter (magenta) expressed in response to neuronal activity marker (cyan) in the hippocampus (Image courtesy of Sho Watanabe/Rice University)

Blood-Based Method Tracks Gene Activity in the Living Brain

A novel blood-based method enables gene transcription measurement in the living brain for the first time. Read more
04 Jun 2026 | Pathology
Image: The Prosigna test provides clinicians and patients with genomic insights to help make more informed breast cancer treatment decisions (Photo courtesy of Veracyte)

Genomic Test Guides Chemotherapy Decisions in Early-Stage Breast Cancer

A new test estimates 10-year distant recurrence and predicts chemotherapy benefit in early HR+ breast cancer to guide treatment. Read more
04 Jun 2026 | Molecular Diagnostics
Image: Representational Models of Regional Aβ and Tau Deposition Across Plasma Stages (Salvadó G, Horie K, Barthélemy NR, et al. JAMA Neurology. May 26, 2026. doi:10.1001/jamaneurol.2026.1405)

Simple Dual-Tau Blood Test Detects and Stages Alzheimer’s Disease

A new two-tau blood test detects and stages Alzheimer's with PET-like accuracy, enabling less invasive routine assessment. Read more
03 Jun 2026 | Clinical Chem.
Image: The approval expands PD-L1 testing on Dako Omnis beyond the assay’s previously cleared indications in non-small cell lung cancer and head and neck squamous cell carcinoma (Photo courtesy of Agilent)

FDA Approval Expands Automated PD-L1 Testing Across Solid Tumors

Agilent’s PD-L1 IHC 22C3 pharmDx has received FDA approval on Dako Omnis to support patient treatment decisions with pembrolizumab. Read more
03 Jun 2026 | Pathology
Image: Cancer study findings showed that extensive chromosome loss is more widespread than previously recognized and often linked to harder-to-treat unstable tumors (image credit: Adobe Stock)

Simple Cytogenetic Method Could Improve Classification of ALL Subtypes

Researchers demonstrate evidence of widespread chromosome loss across cancers and a simple method to distinguish similar-looking ALL subtypes. Read more
03 Jun 2026 | Molecular Diagnostics

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Urine-Based Test Shows Promise for Autism Screening in Children
Liquid Biopsy Biomarkers May Improve Childhood Epilepsy Diagnosis
Blood-Based Sensor Detects Early Signs of Alzheimer’s and Parkinson’s
Image: The study addressed whether circulating markers of hallmark Alzheimer’s pathology align with subtle cognitive differences before clinical diagnosis (image credit: Adobe Stock)

Alzheimer’s Blood Biomarkers Linked to Early Cognitive Differences Before Dementia

Blood-based screening for Alzheimer’s disease offers a noninvasive, lower-cost alternative to brain imaging or spinal fluid testing, yet its ability to flag the earliest cognitive changes has been unclear.... Read more

Molecular Diagnostics

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Tumor Mutation Marker Helps Refine Lung Cancer Prognosis and Guide Therapy Selec...
Multi-Cancer Test Boosts Detection When Added to Standard Screening
Blood-Based MRD Monitoring Supports Relapse Prevention in Leukemia
Image: The blood-based assay captures circulating chromatin, cell-free DNA fragments that are largely inaccessible through standard laboratory methods (image credit: Shuttertstock)

Blood-Based Assay Enables Noninvasive Monitoring of Sarcoma Immunotherapy Response

Sarcomas remain difficult to monitor during immunotherapy, as low tumor mutation burden can limit traditional circulating tumor DNA approaches and repeat tissue biopsies are often impractical in advanced disease.... Read more

Hematology

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Blood Eosinophil Count May Predict Cancer Immunotherapy Response and Toxicity
Higher Ferritin Threshold May Improve Iron Deficiency Detection in Children
Stem Cell Biomarkers May Guide Precision Treatment in Acute Myeloid Leukemia
Image: Sysmex America’s next generation XR-Series, a hematology solution designed to help busy laboratories deliver fast, reliable results while maintaining efficient workflows (Photo courtesy of Sysmex America)

Next-Generation Hematology Platform Streamlines High-Complexity Lab Workflows

Sysmex America (Chicago, IL, USA) has introduced the next generation XR-Series, centered on the XR-10 Automated Hematology Module for high-complexity laboratories. The platform builds on the widely used... Read more

Immunology

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Metabolic Biomarker Distinguishes Latent from Active Tuberculosis and Tracks Tre...
Immune Enzyme Linked to Treatment-Resistant Inflammatory Bowel Disease
Simple Blood Test Could Replace Biopsies for Lung Transplant Rejection Monitorin...
Image: New research shows that autoimmunity drives debilitating long COVID symptoms in a subset of patients (Image credit: Shutterstock)

Study Points to Autoimmune Pathway Behind Long COVID Symptoms

Long COVID leaves many SARS-CoV-2 survivors with persistent fatigue, cognitive issues, palpitations, and musculoskeletal pain for months or years. Estimates cited in new research suggest 4%–20% of infected... Read more

Microbiology

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FDA-Cleared Gastrointestinal Panel Detects 24 Pathogen Targets
New AMR Assay Supports Rapid Infection Control Screening in Hospitals
Diagnostic Gaps Complicate Bundibugyo Ebola Outbreak Response in Congo
Image: Graphical Abstract (Microbiome Research Reports: DOI:10.20517/mrr.2025.96)

Gut Microbiome Signatures Help Identify Risk of IBD Progression

Inflammatory bowel disease (IBD), encompassing Crohn’s disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract with highly variable outcomes.... Read more

Pathology

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AI Tool Extracts Immune Signals from Biopsy to Inform Myeloma Therapy
Rapid AI Tool Predicts Cancer Spatial Gene Expression from Pathology Images
AI Pathology Test Receives FDA Breakthrough for Bladder Cancer Risk Stratificati...
Image: Spatial organization of TLSs within the tumor microenvironment. Image shows TLSs containing T cells (green), B cells (pink), and follicular dendritic cells (cyan), surrounded by tumor cells (red) and stromal cells (yellow) (Photo courtesy of The University of Texas MD Anderson Cancer Center)

AI-Powered Atlas Maps Immune Structures Linked to Cancer Outcomes

Tertiary lymphoid structures are emerging as important indicators of antitumor immunity, but their heterogeneity and spatial context within tumors remain difficult to capture through routine diagnostics.... Read more

Technology

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Agentic AI Platform Supports Genomic Decision-Making in Oncology
Mailed Screening Kits Help Reduce Colorectal Cancer Screening Gaps
Algorithm Panel Aids Liver Fibrosis Assessment and Liver Cancer Surveillance
Image: Foundation Medicine will launch advanced digital solutions integrated with Roche’s navify Clinical Hub to deliver personalized insights to U.S. providers at the point of care (Photo courtesy of Roche)

AI Platform Links Biomarker Results to Cancer Clinical Trials and Guidelines

Oncology teams must manage growing volumes of genomic data, rapidly evolving clinical trial options, and frequently updated care guidelines, all within tight clinic schedules. Translating complex tumor... Read more

Industry

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Partnership Expands Access to Alzheimer’s Blood Tests in Latin America and Carib...
Global Multiplex Assays Market Driven by High-Throughput Diagnostic Demand
Global Framework Integrates Digital Pathology for Companion Diagnostic Developme...
By integrating CLC’s business, Diazyme aims to strengthen its clinical chemistry offering and broaden its diagnostic solutions for laboratories.

Diazyme Laboratories Acquires Carolina Liquid Chemistries

Diazyme Laboratories, Inc. (Poway, CA, USA), a diagnostics company developing enzyme and immunoassay-based test reagents, has acquired the business of Carolina Liquid Chemistries Corporation (CLC, Greensboro,... Read more

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