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AI-Powered Lung Maturity Test Identifies Newborns at Higher Risk of Respiratory Distress

EuroMedLab 2025 Showcases Latest Technologies and Innovations in Laboratory Medicine

First-Of-Its-Kind Device Profiles Newborns' Immune Function Using Single Blood Drop

First Ever Technology Recognizes Disease Biomarkers Directly in Menstrual Blood in Sanitary Towels

Rapid Bedside Test Predicts Sepsis with Over 90% Accuracy

Ultra-Rapid Genetic Test Diagnoses Brain Tumors in Two Hours

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New Sensor Array Quantifies Wound Biomarkers in Real Time for Faster Healing

Traditional Diagnostic Decision Support Systems Outperform Generative AI for Diagnosing Disease

Tiny Implantable Battery Shrinks Tumor Size By 99% In Two Weeks

Diagnostic Algorithm to Reduce Hospitalization for Children with Sickle Cell Disease

Advanced Imaging Endoscopes to Revolutionize Detection and Treatment of Gastrointestinal Disorders

Genetic Testing and Blood-Based Monitoring Improve Understanding and Tracking of Prostate Cancer

Image: ctDNA analysis has proved effective in monitoring tumor evolution and resistance mechanisms in real time (Photo courtesy of 123RF)

Certain gene mutations may be key to understanding outcomes in men with aggressive prostate cancer facing high recurrence rates.
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02 Jun 2025

Digital Diagnostic Platform Uses Electronic Technology for Rapid Disease Detection

02 Jun 2025

Breath Test to Enable Early Detection of Breast Cancer

02 Jun 2025

Novel Assay Determines Medication Received by Hemophilic Patients

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ML Algorithm Accurately Identifies Cancer-Specific Structural in Long-Read DNA Sequencing Data

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Image: The partnership will initially focus on digital and computational pathology products and AI-assisted algorithms (Photo courtesy of Leica Biosystems)

Danaher and AstraZeneca Partner on Next Generation AI-Powered Diagnostics

Danaher Corporation (Washington, D.C., USA) has entered into a partnership with AstraZeneca (Cambridge, UK to develop and commercialize novel diagnostic tools and tests intended to help clinicians better determine which patients would most benefit from precision medicine treatments. Read more
30 May 2025 | Industry

Image: A new diagnostic tool shines a powerful new light into the viral darkness (Photo courtesy of Adobe Stock)

Portable Diagnostic Tool Uses Bioluminescence to Detect Viruses at POC

Point-of-care diagnostics have become crucial tools in many households, enabling individuals to measure blood sugar, conduct pregnancy tests, and even perform their own COVID-19 assays. Read more
30 May 2025 | Clinical Chem.

Image: The innovative doublet configuration and annular illumination overcome traditional metalens limitations (Photo courtesy of Tao Li and Jiacheng Sun/Nanjing University)

High-Resolution Metalens Doublet Microscope to Enhance Diagnostic Capabilities

Metalenses mark a groundbreaking leap in optical technology. Unlike traditional microscope objectives that rely on curved glass surfaces, metalenses utilize nanoscale structures to manipulate light at a subwavelength level. Read more
29 May 2025 | Pathology

Image: New biomarkers could someday make it easy to spot Parkinson’s disease in a patient’s blood sample (Photo courtesy of Shutterstock)

Unique Blood-Based Genetic Signature Can Diagnose Parkinson’s Disease

Parkinson's disease is primarily recognized for its impact on the central nervous system. Recent scientific progress has shifted focus to understanding the involvement of the immune system in the onset and progression of the disease. Read more
29 May 2025 | Molecular Diagnostics

Image: PowerBlade is a portable device that uses a drop of blood and an automated sequence of steps to efficiently detect sepsis (Photo courtesy of NRC)

Rapid Bedside Test Predicts Sepsis with Over 90% Accuracy

Sepsis is a severe response to an infection that causes the immune system to attack the body's own organs and tissues, potentially leading to organ failure and death if not addressed promptly. Read more
28 May 2025 | Microbiology

Image: The new study findings emphasize the need for incorporating disease heterogeneity into type 2 diabetes care strategies (Photo courtesy of Cell 2025; doi.org/10.1016/j.cell.2025.05.00)

Molecular Fingerprint for Insulin Sensitivity Could Diagnose Diabetes Before Disease Develops

Insulin is a hormone essential for regulating blood sugar levels, and its dysfunction is a key factor in the development of diabetes. Read more
28 May 2025 | Molecular Diagnostics

Image: Concept of biosensor integrated into hygiene pads enabling direct semi-quantitative analysis of biomarkers in unprocessed menstruation blood (Photo courtesy of Dosnon, L et al. DOI: 10.1002/advs.202505170)

First Ever Technology Recognizes Disease Biomarkers Directly in Menstrual Blood in Sanitary Towels

Over 1.8 billion people menstruate worldwide, yet menstrual blood has been largely overlooked in medical practice. Read more
28 May 2025 | Technology

Image: A biomarker-based test could evaluate the status of the small blood vessels that can affect kidney function (Photo courtesy of Shutterstock)

Crucial Biomarker Discovery to Enable Early Diagnosis of Chronic Renal Failure

Millions of tiny blood vessels, known as peritubular capillaries, play a crucial role in kidney function by filtering waste from the blood and supplying oxygen and nutrients to the organ. Read more
27 May 2025 | Molecular Diagnostics

Image: Results of AI-based 3D virtual H&E staining and quantitative analysis of pathological tissue (Photo courtesy of Nature Communications, DOI:10.1038/s41467-025-59820-0)

Virtual Staining Technology Paves Way for Non-Invasive Pathological Diagnosis

For more than 200 years, traditional pathology has depended on the technique of examining cancer tissues under a microscope, a method that provides only limited, specific cross-sections of the 3D structure of cancer cells. Read more
27 May 2025 | Pathology

Image: Custom hardware and software for the real-time detection of immune cell biophysical signatures in NICU (Photo courtesy of Pediatric Research, DOI:10.1038/s41390-025-03952-y)

First-Of-Its-Kind Device Profiles Newborns' Immune Function Using Single Blood Drop

Premature infants are highly susceptible to severe and life-threatening conditions, such as sepsis and necrotizing enterocolitis (NEC). Read more
27 May 2025 | Immunology

Image: Early prediction of preterm birth in cell-free RNA could revolutionize prevention strategies (Photo courtesy of 123RF)

Blood Cell-Free RNA Signatures Can Predict Preterm Birth Four Months Before Delivery

Every year, around 13.4 million babies are born prematurely worldwide, accounting for roughly one in ten of all live births. Read more
26 May 2025 | Molecular Diagnostics

Image: Metagenomic next-generation sequencing can achieve early detection of pathogens (Photo courtesy of Shutterstock)

DNA Test Detects Three Times More Lung Pathogens Than Traditional Methods

Traditional microbiological tests (CMTs) used for detecting pathogens typically rely on methods such as culture growth, microscopy, and targeted PCR assays. Read more
26 May 2025 | Molecular Diagnostics

Image: The blood test can aid diagnosis of rare diseases in babies and children (Photo courtesy of 123RF)

Rapid Blood Test Diagnoses Thousands of Rare Genetic Diseases

Although rare genetic diseases are uncommon, there are over 7,000 different diseases caused by mutations in more than 5,000 known genes, affecting around 300 million people globally. Read more
26 May 2025 | Molecular Diagnostics

Image: A biomarker discovery pipeline has shown promise as a noninvasive method of diagnosing CRC (Photo courtesy of NCI Center for Cancer Research)

Machine Learning Tool Enables Noninvasive Diagnosis and Monitoring of Colorectal Cancer

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States when considering both genders. Read more
23 May 2025 | Pathology

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Clinical Chemistry

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Image: The POC device rapidly predicts neonatal respiratory disease at birth in the NICU (Photo courtesy of SIME Diagnostics)

AI-Powered Lung Maturity Test Identifies Newborns at Higher Risk of Respiratory Distress

Each year, approximately 300,000 babies in the United States are born between 32 and 36 weeks' gestation, according to national health data. This group is at an elevated risk for respiratory distress,... Read more

Image: The GlycoLocate platform uses multi-omics and advanced computational biology algorithms to diagnose early-stage cancers (Photo courtesy of AOA Dx)

AI-Powered Blood Test Accurately Detects Ovarian Cancer

Ovarian cancer ranks as the fifth leading cause of cancer-related deaths in women, largely due to late-stage diagnoses. Although over 90% of women exhibit symptoms in Stage I, only 20% are diagnosed in... Read more

Image: The researchers detected genomic alterations from plasma cfDNA (Photo courtesy of 123RF)

Automated Decentralized cfDNA NGS Assay Identifies Alterations in Advanced Solid Tumors

Current circulating cell-free DNA (cfDNA) assays are typically centralized, requiring specialized handling and transportation of samples. Introducing a flexible, decentralized sequencing system at the... Read more

Image: Professor Nicole Strittmatter (left) and first author Wei Chen stand in front of the mass spectrometer with a tissue sample (Photo courtesy of Robert Reich/TUM)

Mass Spectrometry Detects Bacteria Without Time-Consuming Isolation and Multiplication

Speed and accuracy are essential when diagnosing diseases. Traditionally, diagnosing bacterial infections involves the labor-intensive process of isolating pathogens and cultivating bacterial cultures,... Read more

Molecular Diagnostics

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Image: Professor Sofie Degerman led the study analyzing DNA methylation patterns in leukemia cells (Photo courtesy of Mattias Pettersson)

DNA Methylation Analysis Improves Risk Assessment of Childhood Leukemia for Personalizing Treatment

Medical healthcare has made significant progress in treating childhood leukemia, leading to improved survival rates, but the intensive treatments often come with serious side effects. For T-cell acute... Read more

Image: Pancreatic tumor DNA in circulation can be used by novel AI blood test to determine response to cancer therapy (Photo courtesy of Carolyn Hruban)

Novel AI Blood Test Determines Response to Cancer Therapy

Expanding treatment options for pancreatic cancer patients is vital as more experimental therapies become available for the condition. However, swift action is essential, as many pancreatic cancer cases... Read more

Image: The test is highly accurate in detecting HPV-associated head and neck cancers in both asymptomatic and symptomatic patients (Photo courtesy of 123RF)

New Blood Test Shows Superior Sensitivity in Detecting HPV-Associated Head and Neck Cancers

Human papillomavirus (HPV) is responsible for approximately 70% of oropharyngeal cancers in the United States, a cancer type that is rising in incidence more rapidly than all other head and neck cancers.... Read more

Image: ROBIN, a software tool based on the P2 PromethION nanopore sequencers (Photo courtesy of Oxford Nanopore Technology)

Ultra-Rapid Genetic Test Diagnoses Brain Tumors in Two Hours

The standard process for treating brain tumors typically begins with an MRI scan to detect the presence of a tumor. Afterward, patients meet with clinicians to discuss potential tumor types.... Read more

Hematology

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Image: CitoCBC is the world first cartridge-based CBC to be granted CLIA Waived status by FDA (Photo courtesy of CytoChip)

Disposable Cartridge-Based Test Delivers Rapid and Accurate CBC Results

Complete Blood Count (CBC) is one of the most commonly ordered lab tests, crucial for diagnosing diseases, monitoring therapies, and conducting routine health screenings. However, more than 90% of physician... Read more

Image: The FINDER multifunctional testing platform can run multiple types of tests and deliver rapid results for near-patient use (Photo courtesy of Baebies)

First Point-of-Care Heparin Monitoring Test Provides Results in Under 15 Minutes

Heparin dosing requires careful management to avoid both bleeding and clotting complications. In high-risk situations like extracorporeal membrane oxygenation (ECMO), mortality rates can reach about 50%,... Read more

Image: The 3-parameter CCRS model was devised specifically for patients diagnosed with clonal cytopenia (Photo courtesy of 123RF)

New Scoring System Predicts Risk of Developing Cancer from Common Blood Disorder

Clonal cytopenia of undetermined significance (CCUS) is a blood disorder commonly found in older adults, characterized by mutations in blood cells and a low blood count, but without any obvious cause or... Read more

Image: The technology has the unique ability to detect challenging RhD variants that are typically excluded by other commercial tests (Photo courtesy of BillionToOne)

Non-Invasive Prenatal Test for Fetal RhD Status Demonstrates 100% Accuracy

In the United States, approximately 15% of pregnant individuals are RhD-negative. However, in about 40% of these cases, the fetus is also RhD-negative, making the administration of RhoGAM unnecessary.... Read more

Immunology

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Image: The cancer stem cell test can accurately choose more effective treatments (Photo courtesy of University of Cincinnati)

Stem Cell Test Predicts Treatment Outcome for Patients with Platinum-Resistant Ovarian Cancer

Epithelial ovarian cancer frequently responds to chemotherapy initially, but eventually, the tumor develops resistance to the therapy, leading to regrowth. This resistance is partially due to the activation... Read more

Machine Learning-Enabled Blood Test Predicts Immunotherapy Response in Lymphoma Patients

Chimeric antigen receptor (CAR) T-cell therapy has emerged as one of the most promising recent developments in the treatment of blood cancers. However, over half of non-Hodgkin lymphoma (NHL) patients... Read more

Post-Treatment Blood Test Could Inform Future Cancer Therapy Decisions

In the ongoing advancement of personalized medicine, a new study has provided evidence supporting the use of a tool that detects cancer-derived molecules in the blood of lung cancer patients years after... Read more

Cerebrospinal Fluid Test Predicts Dangerous Side Effect of Cancer Treatment

In recent years, cancer immunotherapy has emerged as a promising approach where the patient's immune system is harnessed to fight cancer. One form of immunotherapy, called CAR-T-cell therapy, involves... Read more

Microbiology

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Image: The new prototype blood test for infectious diseases is designed to be delivered and analyzed at the POC (Photo courtesy of Abertay University)

New Blood Test Detects Up to Five Infectious Diseases at POC

Researchers have developed a prototype flow-through assay capable of detecting up to five different infections, with results that can be quickly analyzed and transmitted via a specialized smartphone app.... Read more

Image: The molecular stool test could improve detection of tuberculosis in adults with HIV (Photo courtesy of ISGlobal/George William Kasule et al, 2025)

Molecular Stool Test Shows Potential for Diagnosing TB in Adults with HIV

Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis, led to 1.25 million deaths in 2023, with 13% of those occurring in people living with HIV. The current primary diagnostic method for... Read more

Image: CRP protein in cerebrospinal fluid was found to be a very reliable indicator of bacterial meningitis (Photo courtesy of 123RF)

New Test Diagnoses Bacterial Meningitis Quickly and Accurately

Bacterial meningitis is a potentially fatal condition, with one in six patients dying and half of the survivors experiencing lasting symptoms. Therefore, rapid diagnosis and treatment are critical.... Read more

Image: The lab-in-tube assay could improve TB diagnoses in rural or resource-limited areas (Photo courtesy of Kenny Lass/Tulane University)

Handheld Device Delivers Low-Cost TB Results in Less Than One Hour

Tuberculosis (TB) remains the deadliest infectious disease globally, affecting an estimated 10 million people annually. In 2021, about 4.2 million TB cases went undiagnosed or unreported, mainly due to... Read more

Pathology

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Image: This image shows a second-generation version of the device that can also measure cell morphology (Photo courtesy of MIT)

Rapid Cell Density Measurement Technique to Help Predict Immunotherapy Response

The density of a cell provides valuable insights into its condition. As cells go through processes such as proliferation, differentiation, or cell death, they may gain or lose water and other molecules,... Read more

New Optical Imaging Technology to Improve Diagnosis of Diabetic Kidney Disease

A team of researchers has developed a groundbreaking method to examine kidney tissues without the need for staining or causing damage to the samples. This innovative approach, known as label-free multimodal... Read more

Next-Generation Total Lab Automation Solution Boosts Performance and Productivity

A new total lab automation system premiering in Europe is expected to set new benchmarks in flexibility, user experience, and performance. FlexLab X, the next-generation automation system from Inpeco... Read more

Image: AI-analyzed images from the FDM microscope show platelet clumps in motion (Photo courtesy of Hirose et al CC-BY-ND)

AI Microscope Spots Deadly Blood Clots Before They Strike

Platelets are small blood cells that act as emergency responders in the body, rushing to areas of injury to help stop bleeding by forming clots. However, sometimes platelets can overreact, leading to complications.... Read more

Technology

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Image: Scanning electron microscopy images showing 3D micro-printed Limacon-shaped whispering-gallery-mode microcavities with different amounts of deformation (Photo courtesy of A. Ping Zhang/PolyU)

Tiny Microlaser Sensors with Supercharged Biosensing Ability to Enable Early Disease Diagnosis

Optical whispering-gallery-mode microlaser sensors function by trapping light within tiny microcavities. When target molecules bind to the cavity, they induce subtle changes in the laser’s frequency, allowing... Read more

Advanced Predictive Algorithms Identify Patients Having Undiagnosed Cancer

Two newly developed advanced predictive algorithms leverage a person’s health conditions and basic blood test results to accurately predict the likelihood of having an undiagnosed cancer, including ch... Read more

Light Signature Algorithm to Enable Faster and More Precise Medical Diagnoses

Every material or molecule interacts with light in a unique way, creating a distinct pattern, much like a fingerprint. Optical spectroscopy, which involves shining a laser on a material and observing how... Read more

Image: The HIV-1 self-testing chip will be capable of selectively detecting HIV in whole blood samples (Photo courtesy of Shutterstock)

Disposable Microchip Technology Could Selectively Detect HIV in Whole Blood Samples

As of the end of 2023, approximately 40 million people globally were living with HIV, and around 630,000 individuals died from AIDS-related illnesses that same year. Despite a substantial decline in deaths... Read more

Industry

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Image: EUROMEDLAB is the largest international gathering of laboratory professionals and scientists in Europe (Photo courtesy of IFCC)

EuroMedLab 2025 Showcases Latest Technologies and Innovations in Laboratory Medicine

The 26th IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicine (EuroMedLab 2025), hosted by the Royal Belgian Society of Laboratory Medicine (RBSLM, Verviers, Belgium), in collaboration... Read more

Image: QIAGEN has enhanced its leading clinical genomics portfolio with the acquisition of Genoox AI-powered software (Photo courtesy of Genoox)

Qiagen Acquires NGS Analysis Software Company Genoox

QIAGEN (Venlo, the Netherlands) has signed a definitive agreement to acquire Genoox (Tel Aviv, Israel), a provider of artificial intelligence (AI)-powered software that enables clinical labs to scale and... Read more

$Image: The collaboration aims to leverage Oxford Nanopore\'s sequencing platform and Cepheid\'s GeneXpert system to advance the field of sequencing for infectious diseases (Photo courtesy of Cepheid)$

Cepheid and Oxford Nanopore Technologies Partner on Advancing Automated Sequencing-Based Solutions

Cepheid (Sunnyvale, CA, USA), a leading molecular diagnostics company, and Oxford Nanopore Technologies (Oxford, UK), the company behind a new generation of sequencing-based molecular analysis technologies,... Read more

Image: The Grifols-IBL partnership will initially focus on biomarker panels for neurological and oncological conditions (Photo courtesy of Grifols)

Grifols and Tecan’s IBL Collaborate on Advanced Biomarker Panels

Grifols (Barcelona, Spain), one of the world’s leading producers of plasma-derived medicines and innovative diagnostic solutions, is expanding its offer in clinical diagnostics through a strategic partnership... Read more

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