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In Other News

Image: Under the agreement, Natera will evaluate ctDNA from clinical trial samples collected in CytoDyn’s CLOVER Phase 2 study

Collaboration Advances ctDNA-Guided Development in Metastatic Colorectal Cancer

A personalized ctDNA-based MRD test assesses residual disease and response in metastatic CRC to inform leronlimab development. Read more
08 Jun 2026 | Industry
Image: In ALT-positive cancers, researchers found that centromere-associated DNA can be inserted near telomeres at chromosome ends (Image credit: Shutterstock)

Researchers Uncover Distinct Chromosome Signature in Aggresive ALT Cancers

New findings reveal a previously unseen chromosome interaction in alternative lengthening of telomeres positive (ALT+) tumors Read more
04 Jun 2026 | Molecular Diagnostics
Image: RMA reporter (magenta) expressed in response to neuronal activity marker (cyan) in the hippocampus (Image courtesy of Sho Watanabe/Rice University)

Blood-Based Method Tracks Gene Activity in the Living Brain

A novel blood-based method enables gene transcription measurement in the living brain for the first time. Read more
04 Jun 2026 | Pathology
Image: The Prosigna test provides clinicians and patients with genomic insights to help make more informed breast cancer treatment decisions (Photo courtesy of Veracyte)

Genomic Test Guides Chemotherapy Decisions in Early-Stage Breast Cancer

A new test estimates 10-year distant recurrence and predicts chemotherapy benefit in early HR+ breast cancer to guide treatment. Read more
04 Jun 2026 | Molecular Diagnostics
Image: Representational Models of Regional Aβ and Tau Deposition Across Plasma Stages (Salvadó G, Horie K, Barthélemy NR, et al. JAMA Neurology. May 26, 2026. doi:10.1001/jamaneurol.2026.1405)

Simple Dual-Tau Blood Test Detects and Stages Alzheimer’s Disease

A new two-tau blood test detects and stages Alzheimer's with PET-like accuracy, enabling less invasive routine assessment. Read more
03 Jun 2026 | Clinical Chem.
Image: The approval expands PD-L1 testing on Dako Omnis beyond the assay’s previously cleared indications in non-small cell lung cancer and head and neck squamous cell carcinoma (Photo courtesy of Agilent)

FDA Approval Expands Automated PD-L1 Testing Across Solid Tumors

Agilent’s PD-L1 IHC 22C3 pharmDx has received FDA approval on Dako Omnis to support patient treatment decisions with pembrolizumab. Read more
03 Jun 2026 | Pathology
Image: Cancer study findings showed that extensive chromosome loss is more widespread than previously recognized and often linked to harder-to-treat unstable tumors (image credit: Adobe Stock)

Simple Cytogenetic Method Could Improve Classification of ALL Subtypes

Researchers demonstrate evidence of widespread chromosome loss across cancers and a simple method to distinguish similar-looking ALL subtypes. Read more
03 Jun 2026 | Molecular Diagnostics
By integrating CLC’s business, Diazyme aims to strengthen its clinical chemistry offering and broaden its diagnostic solutions for laboratories.

Diazyme Laboratories Acquires Carolina Liquid Chemistries

The acquisition brings together Diazyme’s proprietary enzyme and immunoassay technologies with CLC’s cost-effective chemistry systems and reagents. Read more
03 Jun 2026 | Industry
Image: The study addressed whether circulating markers of hallmark Alzheimer’s pathology align with subtle cognitive differences before clinical diagnosis (image credit: Adobe Stock)

Alzheimer’s Blood Biomarkers Linked to Early Cognitive Differences Before Dementia

For the first time, researchers found Alzheimer’s blood biomarkers linked to minor cognitive differences in midlife adults without dementia. Read more
03 Jun 2026 | Clinical Chem.
Image: The blood-based assay captures circulating chromatin, cell-free DNA fragments that are largely inaccessible through standard laboratory methods (image credit: Shuttertstock)

Blood-Based Assay Enables Noninvasive Monitoring of Sarcoma Immunotherapy Response

A new cfDNA assay captures immune, stromal and tumor signals to monitor immunotherapy response and resistance in sarcoma Read more
03 Jun 2026 | Molecular Diagnostics
Image: Through the collaboration with SouthGenetics, healthcare professionals across Latin America and the Caribbean will gain access to C2N’s Precivity portfolio of blood tests

Partnership Expands Access to Alzheimer’s Blood Tests in Latin America and Caribbean

C2N Diagnostics and SouthGenetics have partnered to expand access to Precivity blood tests for Alzheimer’s disease assessment across Latin America and the Caribbean. Read more
02 Jun 2026 | Industry
Image: Findings showed that TP53 mutations correlate with lung cancer prognosis and may help guide therapy selection(image credit: Adobe Stock)

Tumor Mutation Marker Helps Refine Lung Cancer Prognosis and Guide Therapy Selection

New data show TP53 mutations in lung cancer predict poorer prognosis and guide selection between EGFR therapy and chemotherapy. Read more
02 Jun 2026 | Molecular Diagnostics
PATHFINDER 2 Study: Screen Detected Cancers (Photo courtesy of GRAIL)

Multi-Cancer Test Boosts Detection When Added to Standard Screening

PATHFINDER 2 study findings show that GRAIL’s Galleri MCED test increased cancer detection 6.5-fold when added to recommended cancer screening. Read more
02 Jun 2026 | Molecular Diagnostics
Image: Findings show that MRD‑guided intervention demonstrated the potential to delay or possibly prevent leukemic relapse (image credit: Shutterstock)

Blood-Based MRD Monitoring Supports Relapse Prevention in Leukemia

New long-term data show MRD-triggered therapy may delay or prevent relapse in MDS and AML. Read more
01 Jun 2026 | Molecular Diagnostics

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Clinical Chemistry

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Liquid Biopsy Biomarkers May Improve Childhood Epilepsy Diagnosis
Blood-Based Sensor Detects Early Signs of Alzheimer’s and Parkinson’s
Urine-Based Alzheimer’s Test Receives FDA Breakthrough Device Designation
Image: New urine test provides a simple way to screen for autism in children (Photo courtesy of Andy DeLisle/ASU Knowledge Enterprise)

Urine-Based Test Shows Promise for Autism Screening in Children

Autism spectrum disorder (ASD) is commonly diagnosed through behavioral assessments, which can involve long waits that delay intervention. Earlier identification is linked to better developmental outcomes,... Read more

Molecular Diagnostics

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Blood Protein Markers Flag Multiple Sclerosis Risk Years Before Diagnosis
Updated Guidance Prioritizes Stool-Based Colorectal Cancer Screening Tests
Digital PCR Assays Support Surveillance of Bundibugyo Ebolavirus Outbreak
Image: The Decipher Prostate test can guide treatment decisions in metastatic prostate cancer (Photo courtesy of Veracyte)

Genomic Test Predicts Chemotherapy Benefit in Metastatic Prostate Cancer

Metastatic prostate cancer remains a major treatment challenge, particularly when deciding whether to add chemotherapy to hormonal therapy. In the United States, about 334,000 men are diagnosed with prostate... Read more

Hematology

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Blood Eosinophil Count May Predict Cancer Immunotherapy Response and Toxicity
Higher Ferritin Threshold May Improve Iron Deficiency Detection in Children
Stem Cell Biomarkers May Guide Precision Treatment in Acute Myeloid Leukemia
Image: Sysmex America’s next generation XR-Series, a hematology solution designed to help busy laboratories deliver fast, reliable results while maintaining efficient workflows (Photo courtesy of Sysmex America)

Next-Generation Hematology Platform Streamlines High-Complexity Lab Workflows

Sysmex America (Chicago, IL, USA) has introduced the next generation XR-Series, centered on the XR-10 Automated Hematology Module for high-complexity laboratories. The platform builds on the widely used... Read more

Immunology

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Metabolic Biomarker Distinguishes Latent from Active Tuberculosis and Tracks Tre...
Immune Enzyme Linked to Treatment-Resistant Inflammatory Bowel Disease
Simple Blood Test Could Replace Biopsies for Lung Transplant Rejection Monitorin...
Image: New research shows that autoimmunity drives debilitating long COVID symptoms in a subset of patients (Image credit: Shutterstock)

Study Points to Autoimmune Pathway Behind Long COVID Symptoms

Long COVID leaves many SARS-CoV-2 survivors with persistent fatigue, cognitive issues, palpitations, and musculoskeletal pain for months or years. Estimates cited in new research suggest 4%–20% of infected... Read more

Microbiology

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FDA-Cleared Gastrointestinal Panel Detects 24 Pathogen Targets
New AMR Assay Supports Rapid Infection Control Screening in Hospitals
Diagnostic Gaps Complicate Bundibugyo Ebola Outbreak Response in Congo
Image: Graphical Abstract (Microbiome Research Reports: DOI:10.20517/mrr.2025.96)

Gut Microbiome Signatures Help Identify Risk of IBD Progression

Inflammatory bowel disease (IBD), encompassing Crohn’s disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract with highly variable outcomes.... Read more

Pathology

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AI Tool Extracts Immune Signals from Biopsy to Inform Myeloma Therapy
Rapid AI Tool Predicts Cancer Spatial Gene Expression from Pathology Images
AI Pathology Test Receives FDA Breakthrough for Bladder Cancer Risk Stratificati...
Image: Spatial organization of TLSs within the tumor microenvironment. Image shows TLSs containing T cells (green), B cells (pink), and follicular dendritic cells (cyan), surrounded by tumor cells (red) and stromal cells (yellow) (Photo courtesy of The University of Texas MD Anderson Cancer Center)

AI-Powered Atlas Maps Immune Structures Linked to Cancer Outcomes

Tertiary lymphoid structures are emerging as important indicators of antitumor immunity, but their heterogeneity and spatial context within tumors remain difficult to capture through routine diagnostics.... Read more

Technology

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Agentic AI Platform Supports Genomic Decision-Making in Oncology
Mailed Screening Kits Help Reduce Colorectal Cancer Screening Gaps
Algorithm Panel Aids Liver Fibrosis Assessment and Liver Cancer Surveillance
Image: Foundation Medicine will launch advanced digital solutions integrated with Roche’s navify Clinical Hub to deliver personalized insights to U.S. providers at the point of care (Photo courtesy of Roche)

AI Platform Links Biomarker Results to Cancer Clinical Trials and Guidelines

Oncology teams must manage growing volumes of genomic data, rapidly evolving clinical trial options, and frequently updated care guidelines, all within tight clinic schedules. Translating complex tumor... Read more

Industry

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Global Framework Integrates Digital Pathology for Companion Diagnostic Developme...
GRAIL Presents Full Results from NHS-Galleri Trial at ASCO 2026
Werfen and Oxford Nanopore Collaborate on Transplant Assay Development
Photo courtesy of Shutterstock

Global Multiplex Assays Market Driven by High-Throughput Diagnostic Demand

Multiplex assays enable simultaneous detection and measurement of multiple analytes in a single sample, supporting faster analysis across diagnostics, biomarker discovery, drug development, and life sciences... Read more

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