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In Other News

Image: Gustave Roussy is partnering with One Biosciences, a techbio company using single-cell technology and AI to advance precision diagnostics

Partnership Brings Single-Cell Analysis into Clinical Oncology Workflows

Selecting treatments for advanced cancer remains difficult when bulk analyses mask the functional diversity of tumor cells and mechanisms of resistance that emerge over time. Read more
20 May 2026 | Industry
Image: An updated review finds that prostate cancer blood tests likely reduce the risk of death, revising earlier findings that evidence was insufficient (photo courtesy of iStock)

Long-Term Data Show PSA Screening Modestly Reduces Prostate Cancer Deaths

Prostate cancer is among the most common cancers in men, and the role of population screening has remained controversial because of overdiagnosis and overtreatment. Read more
20 May 2026 | Clinical Chem.
Image: Labbit is a modern LIMS platform designed for regulated laboratories managing complex workflows in molecular diagnostics, cell and gene therapy, and quality control manufacturing (photo courtesy of Labbit)

AI Tool Automates Validation of Laboratory Software Configuration Changes

Regulated laboratories face heavy documentation and requalification demands when software configurations change, slowing improvements and discouraging beneficial updates. Read more
20 May 2026 | Technology
Image: Researchers identified eight new DNA pattern signatures that could help refine diagnostics and guide targeted therapy in breast cancer (image credit: 123RF)

Breast Cancer-Specific Signatures Link Genome Instability to Outcomes

Genomic instability is a hallmark of cancer, but most genomic analyses have relied on broad signatures shared across multiple malignancies, limiting their precision for individual tumor types. Read more
19 May 2026 | Molecular Diagnostics
Image: TrueMRD uses a whole-genome, tumor-informed approach that analyzes patient-specific tumor variants across the entire genome in every sample tested (photo courtesy of Veracyte)

Whole-Genome MRD Test Detects Early Recurrence in Muscle-Invasive Bladder Cancer

Bladder cancer is among the most common malignancies in the United States, with about 85,000 new cases each year. Read more
19 May 2026 | Molecular Diagnostics
Image: Researchers found that tumor DNA fragments in blood can reveal ongoing prostate cancer growth even when current tests show little change (image credit: Adobe Stock)

Blood Test Detects Early Nonresponse in Metastatic Prostate Cancer

Prostate cancer is the most common cancer in the U.K., with more than 64,000 men diagnosed and 12,000 deaths each year. Read more
19 May 2026 | Molecular Diagnostics
Image: CellDx-Tissue is a qualitative IVD test that uses targeted NGS of DNA and RNA isolated from FFPE solid tumor tissue to analyze 517 cancer-associated genes (image credit: Adobe Stock)

FDA-Cleared Genomic Profiling Assay Guides Treatment Selection in Solid Tumors

Datar Cancer Genetics (DCG; Nashik, India), a global precision oncology company, has announced that its tissue-based comprehensive genomic profiling (CGP) assay for all solid tumors, CellDx-Tissue, has received U. Read more
19 May 2026 | Molecular Diagnostics
Image: sm-PORE-cupine helps scientists study how individual RNA molecules fold across different transcriptomes (biological samples) (Photo courtesy of A*STAR Genome Institute of Singapore (A*STAR GIS)

Nanopore Method Captures RNA Folding at Single-Molecule Resolution

RNA structure plays a central role in controlling gene expression, yet its dynamic, shape-shifting behavior makes it difficult to study at single-molecule resolution. Read more
19 May 2026 | BioResearch
Image: Findings show that ctDNA testing may help identify candidates for radiotherapy and refine management by signaling when a cancer has changed or developed resistance (image credit: 123RF)

ctDNA Blood Test Could Help Guide Radiotherapy in Patients with Limited Metastases

Selecting the right therapy for patients whose solid tumors have begun to spread remains a major clinical challenge. Read more
18 May 2026 | Molecular Diagnostics
Image: Graphical Abstract (Eldad D. Shulman et al., AI-predicted spatial transcriptomics unlocks breast cancer biomarkers from pathology, Cell (2026). DOI: 10.1016/j.cell.2026.04.023)

Rapid AI Tool Predicts Cancer Spatial Gene Expression from Pathology Images

Gene expression profiling can inform tumor biology and treatment selection, but spatial assays remain costly and time-consuming. Read more
18 May 2026 | Pathology
Image: New findings indicate that clonal hematopoiesis, an established prognostic factor in blood cancers, is associated with worse survival in patients with solid tumors (image credit: Adobe Stock)

Tumor Microenvironment Marker Linked to Worse Survival in Solid Tumors

Risk stratification across solid tumors remains difficult because outcomes can vary widely among patients with the same tumor type. Read more
18 May 2026 | BioResearch
Image: Signatera CDx uses ctDNA analysis to identify residual tumor-derived genetic material after definitive treatment (image credit: Adobe Stock)

FDA-Approved MRD Blood Test Guides Adjuvant Bladder Cancer Therapy

Muscle-invasive bladder cancer (MIBC) carries a substantial risk of recurrence after radical cystectomy, and selecting which patients require adjuvant therapy remains challenging. Read more
18 May 2026 | Molecular Diagnostics
Image: Findings show that genetic changes inside cancer cells may help explain why some patients with gallbladder cancer have poorer outcomes despite similar treatment (image credit: 123RF)

Tumor Genomic Profiling Identifies High-Risk Gallbladder Cancer

Gallbladder cancer is an aggressive biliary tract malignancy that often progresses silently and is frequently diagnosed at an advanced stage. Read more
18 May 2026 | Molecular Diagnostics
Image: The technology leverages routine slide preparations to deliver an individualized risk readout based on image-derived signals (photo courtesy of Valar Labs)

AI Pathology Test Receives FDA Breakthrough for Bladder Cancer Risk Stratification

Non–muscle invasive bladder cancer has highly variable outcomes, complicating surveillance and treatment planning. Read more
18 May 2026 | Pathology

Channels

Clinical Chemistry

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Blood-Based Alzheimer’s Test Gains CE Mark for Amyloid Pathology Detection
FDA-Cleared Assay Enables Comprehensive Automated Testosterone Testing
CE-Marked Blood Biomarker Test Advances Automated Alzheimer’s Diagnostics
Image: Originally designed for lung cancer detection and resistance monitoring, the test also shows potential for identifying signals linked to pulmonary fibrosis (image credit: iStock)

Urine-Based Nanosensor Tracks Lung Cancer and Fibrosis Noninvasively

Lung cancer remains difficult to monitor for early progression and treatment resistance, while pulmonary fibrosis continues to pose major challenges for early diagnosis. Clinicians need repeatable, noninvasive... Read more

Molecular Diagnostics

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Sensitive Protein Marker Aids Diagnosis of Small Cell Prostate Cancer
Rapid Multiplex PCR Test Detects 11 Gastrointestinal Pathogens from Single Sampl...
Novel Algorithm Improves Detection of B-ALL Gene Fusions
Image: The study frames predictive genomic screening as both a clinical opportunity and a systems challenge (photo courtesy of Mayo Clinic)

Genome Sequencing Uncovers Hidden Genetic Risks in Healthy Adults

Genetic risk for serious diseases can go undetected in routine care, limiting opportunities for earlier intervention. Translating genomic data into actionable care plans also creates operational challenges... Read more

Hematology

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Advanced CBC-Derived Indices Integrated into Hematology Platforms
Blood Test Enables Early Detection of Multiple Myeloma Relapse
Single Assay Enables Rapid HLA and ABO Genotyping for Transplant Matching
Image: Graphical abstract (Waclawiczek A, Leppä AM, Renders S, et al. Cell Stem Cell, 2026. doi:10.1016/j.stem.2026.04.012)

Stem Cell Biomarkers May Guide Precision Treatment in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is an aggressive blood cancer that most often affects older adults and still carries a poor prognosis despite therapeutic advances. Venetoclax-based regimens have improved... Read more

Immunology

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Biomarkers and Molecular Testing Advance Precision Allergy Care
Point-of-Care Tests Could Expand Access to Mpox Diagnosis
T-Cell Senescence Profiling May Predict CAR T Responses
Image: The findings suggest IGRA control responses offer a scalable measure of immune function from a widely used clinical assay (image credit: Adobe Stock)

Routine TB Screening Test May Reveal Immune Aging and Mortality Risk

Immune aging is associated with weaker responses to vaccination, greater risks of infection, and higher levels of inflammation. Leveraging routinely ordered laboratory tests to quantify that responsiveness... Read more

Microbiology

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Large-Scale Genomic Surveillance Tracks Resistant Bacteria Across European Hospi...
Molecular Urine and Stool Tests Do Not Improve Early TB Treatment in Hospitalized...
Rapid Antigen Biosensor Detects Active Tuberculosis in One Hour
Image: The findings suggest that people with mpox can transmit the virus even without clinical symptoms (image credit: Adobe Stock)

Study Finds Hidden Mpox Infections May Drive Ongoing Spread

Mpox continues to circulate despite vaccination, and many cases show no known link to a symptomatic partner. The role of people without symptoms has remained uncertain, limiting clarity on how transmission persists.... Read more

Pathology

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New AI Tool Reveals Hidden Genetic Signals in Routine H&E Slides
AI System Analyzes Routine Pathology Slides to Predict Cancer Outcomes
New Tissue Mapping Approach Identifies High-Risk Form of Diabetic Kidney Disease
Image: ArteraAI Breast analyzes digitized histopathology images alongside patient clinical variables to produce an AI-derived risk score that provides prognostic insight into the likelihood of distant metastasis (Image credit: Adobe Stock)

FDA Clears AI Digital Pathology Tool for Breast Cancer Risk Stratification

Risk assessment at diagnosis is central to guiding therapy for early-stage, hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) invasive breast cancer, where overtreatment... Read more

Technology

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Fully Automated Sample-to-Insight Workflow Advances Latent TB Testing
Tumor-on-a-Chip Platform Models Pancreatic Cancer Treatment Response
New Platform Captures Extracellular Vesicles for Early Cancer Detection
Image: A new study shows how point-of-care testing can enhance health literacy and patient confidence (Photo courtesy of Adobe Stock)

Point-of-Care Testing Enhances Health Literacy and Self-Management in Chronic Disease

Limited access to general practitioners and pathology services can delay diagnosis and monitoring for people in regional and remote communities. Rapid, on-the-spot testing can shorten turnaround times... Read more

Industry

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Partnership Aims to Bring Risk-Guided CKD Care to Health Systems
Roche to Acquire PathAI for Up to $1.05 Billion to Strengthen AI Diagnostics Por...
FDA Clears Blood-Based Companion Diagnostic for Advanced Breast Cancer Therapy
Image: Ozelle Wins German Innovation Award Gold (photo courtesy of Ozelle)

AI-Powered Multi-Functional Analyzer Wins German Innovation Award

Hematology services are increasingly delivered across distributed care settings, where limited staffing and complex workflows can extend turnaround times. Advanced morphology review still often depends... Read more

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