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In Other News

Image: a new initiative aims to bring greater precision to this class of therapeutics (Photo courtesy of One Biosciences)

Project Aims to Develop First Single-Cell Assay for ADC Therapies

One Biosciences receives Paris Saclay Cancer Cluster BOOST funding to advance a single-cell assay approach for antibody-drug conjugate therapies. Read more
26 Jun 2026 | Industry
Image: The proposed immunoassay uses ALZpath’s pTau217 antibody to detect Alzheimer’s disease biology in blood, supporting the growing role of blood-based biomarkers in clinical care (Photo courtesy of Shutterstock)

Agreement Supports pTau217-Based Alzheimer’s Blood Test Development

ALZpath is licensing its proprietary pTau217 antibody to Abbott for development of an Alzheimer’s disease IVD test. Read more
26 Jun 2026 | Industry
Image: A four‑protein signature can identify pediatric IBD and distinguish its subtypes (Image credit: iStock)

Blood Protein Signature Diagnoses Pediatric IBD and Distinguishes Subtypes

A new four-protein blood test identifies pediatric IBD and distinguishes Crohn's from ulcerative colitis noninvasively. Read more
25 Jun 2026 | Clinical Chem.
Image: New findings indicate that chimeric RNAs, once viewed as cancer byproducts, can also be part of normal physiology with regulatory functions (Image credit: Adobe Stock)

Female-Specific RNA Biomarker May Help Explain Sex Differences in Immune Disease

Researchers identify a female-specific chimeric RNA that tracks COVID-19 severity, informing blood-based risk stratification. Read more
25 Jun 2026 | Molecular Diagnostics
Image: Blue represents nuclei and pink represents dead or dying cells. Bottom right: Cells are overexpressing the BIRC3 variant which is seen in green. (Photo courtesy of The Hospital for Sick Children)

Genetic Marker Supports Anti-TNF Therapy Selection in Crohn’s Disease

New findings identify Crohn’s-linked genetic changes that may help stratify patients and guide anti-TNF therapy. Read more
25 Jun 2026 | Molecular Diagnostics
Image: An uncertainty‑aware framework strengthens AI reliability for cancer histology subtyping (Image credit: Shutterstock)

Uncertainty-Aware AI Tool Improves Digital Pathology for Cancer Subtyping

An uncertainty-aware AI approach boosts pathology, flagging out-of-scope inputs and meeting accuracy targets in cancer subtyping. Read more
25 Jun 2026 | Pathology
Image: Volition’s Nu.Q NETs test detects markers associated with neutrophil extracellular traps, which are released during NETosis and linked to sepsis and other acute and chronic disorders (Image credit: iStock)

Collaboration Aims to Broaden Access to NETosis-Linked Disease Testing

VolitionRx announced a collaboration with Sysmex Corporation to optimize Volition’s Nu.Q NETs H3.1 assay on the Sysmex platform.  Read more
25 Jun 2026 | Industry
Image: Findings showed that the Stockholm3 blood test detected more clinically significant prostate cancers than PSA testing without increasing unnecessary testing (Image credit: 123RF)

Blood Test Detects More High-Risk Prostate Cancers Than PSA

A new blood test detects more aggressive prostate cancers than PSA without increasing unnecessary testing. Read more
24 Jun 2026 | Clinical Chem.
Image: Biomarker testing is critical for lung cancer therapy selection, yet ordering delays mean biopsy-to-result turnaround still averages about 27 days, according to a new study (image credit: Shutterstock)

Study Highlights Biomarker Testing Delays in Lung Cancer Care

New findings highlight ordering delays as main driver of 27-day biopsy-to-biomarker turnaround, risking delayed targeted therapy. Read more
24 Jun 2026 | Pathology
Image: Hematopoietic stem cells (white), which produce all blood cells in the body, seen alongside blood cells (blue and red) in the bone marrow. (Image credit: Brian Heubel, Passegué laboratory, Columbia Stem Cell Initiative)

Single-Cell Analysis Mapping Links Inflammation Response to Acute Myeloid Leukemia

New findings reveal a single switch for emergency myelopoiesis and tools that map dynamics, linking AML signatures to prognosis. Read more
24 Jun 2026 | BioResearch
Image: The findings represent an important precision oncology milestone, independently confirming that endocrine activity in HR+/HER2− breast tumors can predict sensitivity to specific chemotherapy approaches (Image Credit: Adobe Stock)

Genomic Test Guides Taxane-Based Chemotherapy Selection in Breast Cancer

A new test quantifies tumor endocrine activity to predict which HR+/HER2− tumors benefit from weekly paclitaxel. Read more
24 Jun 2026 | Molecular Diagnostics
Image: At the core of the collaboration is Pirche’s TxPredictor platform, which uses proprietary algorithms to analyze histocompatibility and predict immunological risk (Photo courtesy of Pirche AG)

Partnership Aims to Improve Transplant Monitoring Across Care Continuum

A new partnership links pre-transplant molecular risk stratification with post-transplant dd-cfDNA monitoring. Read more
24 Jun 2026 | Industry
An overview of the study and findings: A) Several brain-derived EVPs cross the blood brain barrier and reach circulation. B) Different EVPs enrich different RNA cargo B) The EVP-RNA is impacted, upregulated (green) or downregulated (red) in AD (Gonzalez-Kozlova, E., et al., Nature Communications (2026). doi.org/10.1038/s41467-026-74541-8)

RNA Blood Test May Enable Earlier Alzheimer’s Disease Diagnosis

New findings show brain-derived RNA in blood nanoparticles enables earlier Alzheimer’s detection via a simple blood test. Read more
23 Jun 2026 | Molecular Diagnostics
Image: NSE-FAST is a rapid, enzyme-based luminescence assay that quantifies neuron specific enolase activity in blood plasma, using TETmedical’s patented Tethered Enzyme Technology to measure this biomarker of acute ischemic stroke (Photo courtesy of TET Medical)

Rapid Blood Test Aids Diagnosis of Acute Ischemic Stroke

A new rapid blood test receives FDA Breakthrough designation to aid acute ischemic stroke diagnosis when early imaging misses. Read more
23 Jun 2026 | Clinical Chem.

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Image: A new study identifies distinct metabolomic signatures in maternal blood associated with both the timing and type of early birth (Image credit: iStock)

Maternal Blood Biomarkers Identify Risk of Preterm and Early-Term Birth

Preterm and early-term births can lead to lasting complications because vital organs continue to mature during the final weeks of pregnancy. Babies born too soon face increased risks of breathing difficulties,... Read more

Molecular Diagnostics

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Point-of-Care Molecular Test Detects Group A Strep in Minutes
Genetic Testing and Surveillance Cuts Costs and Improves Survival in Li-Fraumeni...
Spatial Map Guides Treatment Selection in Muscle-Invasive Bladder Cancer
Image: Experts used an OpenAI reasoning model to reanalyze 376 previously unsolved cases and surface leads for 18 diagnoses (Image credit: iStock)

AI Reasoning Model Generates Diagnostic Leads for Unresolved Rare Disease Cases

Rare genetic diseases often leave families without definitive answers, even after genome sequencing and expert review. As scientific evidence evolves and clinical data remain fragmented across systems,... Read more

Hematology

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Blood Eosinophil Count May Predict Cancer Immunotherapy Response and Toxicity
Higher Ferritin Threshold May Improve Iron Deficiency Detection in Children
Stem Cell Biomarkers May Guide Precision Treatment in Acute Myeloid Leukemia
Image: Sysmex America’s next generation XR-Series, a hematology solution designed to help busy laboratories deliver fast, reliable results while maintaining efficient workflows (Photo courtesy of Sysmex America)

Next-Generation Hematology Platform Streamlines High-Complexity Lab Workflows

Sysmex America (Chicago, IL, USA) has introduced the next generation XR-Series, centered on the XR-10 Automated Hematology Module for high-complexity laboratories. The platform builds on the widely used... Read more

Immunology

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Antibody Profiles Provide Clues to Long COVID Severity and Symptoms
Aptamer-Based Biosensor Enables Mutation-Resilient SARS-CoV-2 Detection
Study Points to Autoimmune Pathway Behind Long COVID Symptoms
Image: Lead author Muhammad Zia Ullah Khan examines a Petri dish containing a cell suspension. Fluorescence and bright-field images of cells in microchannels, displayed on the monitor, visualize immune cell communication (Photo courtesy of Technical University Munich)

Lab-on-a-Chip Approach Advances Immune–Cancer Cell Interaction Analysis

Conventional cytotoxicity assays often average responses across thousands of cells, obscuring how individual immune cells engage and kill tumor cells. For immunotherapy evaluation, the precise sequence... Read more

Microbiology

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Stronger Laboratory Services Support Timely Melioidosis Diagnosis Amid Global Sp...
Extracellular Vesicle Biomarker May Enable Noninvasive Monitoring of H. pylori
Rapid Molecular Screening Aims to Accelerate Hospital Infection Control for CPE
Image: Multidrug-resistant Klebsiella pneumoniae is a growing community health concern, causing recurrent UTIs in older adults and complicating first-line antibiotic treatment (Image Credit: Adobe Stock)

Study Reveals Widespread Community Spread of Drug-Resistant Klebsiella

Multidrug-resistant Klebsiella pneumoniae is an escalating community health concern, driving recurrent urinary tract infections in older adults and complicating first-line antibiotic therapy.... Read more

Pathology

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New Companion Diagnostic Expands Precision Medicine in Prostate Cancer
Uncertainty-Aware AI Platform Supports Automated HER2 Assessment in Breast Cance...
AI Tool Speeds Brain Tumor Classification from Routine Histology Slides
Image: Healthy and cancerous regions in a H&Eble results (Photo courtesy of KAUST)

Stain-Free Imaging Platform Matches Standard Cancer Pathology

Histopathology underpins cancer diagnosis, but turnaround times and inter-laboratory variability can limit timely, consistent interpretation. Conventional staining relies on chemical dyes and multiple... Read more

Technology

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Agentic AI Platform Supports Genomic Decision-Making in Oncology
Mailed Screening Kits Help Reduce Colorectal Cancer Screening Gaps
Algorithm Panel Aids Liver Fibrosis Assessment and Liver Cancer Surveillance
Image: Foundation Medicine will launch advanced digital solutions integrated with Roche’s navify Clinical Hub to deliver personalized insights to U.S. providers at the point of care (Photo courtesy of Roche)

AI Platform Links Biomarker Results to Cancer Clinical Trials and Guidelines

Oncology teams must manage growing volumes of genomic data, rapidly evolving clinical trial options, and frequently updated care guidelines, all within tight clinic schedules. Translating complex tumor... Read more

Industry

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Partnership Expands Ultrasensitive Blood-Based Diagnostics for Hematologic Malig...
Open-Source Consortium Aims to Standardize Digital Pathology Workflows
Genetic Testing Program Expands Detection of Alpha-1 Antitrypsin Deficiency
Photo courtesy of Qiagen

QIAGEN Enhances QIAcuity Platform with Gene Expression and Multiplexing Tools

QIAGEN (Venlo, Netherlands) has introduced additions to its QIAcuity dPCR ecosystem that focus on gene expression, expanded assay content, and workflow standardization for life sciences and biopharma users.... Read more

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