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Whole-Blood RNA Test Predicts Disease Trajectory and Treatment Response

Roche to Acquire PathAI for Up to $1.05 Billion to Strengthen AI Diagnostics Portfolio

New AI Tool Reveals Hidden Genetic Signals in Routine H&E Slides

Liquid Biopsy Biomarkers Distinguish Inflammatory Breast Cancer and Support Monitoring

Ultrasensitive Test Detects Key Biomarker of Frontotemporal Dementia Subtype

FDA Clears AI Digital Pathology Tool for Breast Cancer Risk Stratification

Point-of-Care Tests Could Expand Access to Mpox Diagnosis

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New Diagnostic Marker for Ovarian Cancer to Enable Early Disease Detection

Cell-Sorting Device Uses Electromagnetic Levitation to Precisely Direct Cell Movement

Microneedle Skin Patch Detects Melanoma Without Biopsy or Blood Draw

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21 May 2026 - 21 May 2026

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28 May 2026 - 30 May 2026

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02 Jun 2026 - 04 Jun 2026

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FDA-Cleared AI System Detects Sepsis Earlier and Reduces Mortality

Photoacoustic Imaging System Maps Hidden Nerves and Vessels in Robotic Laparoscopy

High-Frequency Ultrasound Disables Viruses While Sparing Human Cells

New Nasal Spray Enables Prehospital Neuroprotection in Ischemic Stroke

Smart Soft Sensors Provide Real-Time Force Feedback in Minimally Invasive Surgery

Urine-Based Nanosensor Tracks Lung Cancer and Fibrosis Noninvasively

Image: Originally designed for lung cancer detection and resistance monitoring, the test also shows potential for identifying signals linked to pulmonary fibrosis (image credit: iStock)

A new urine test tracks enzyme activity to support earlier, ongoing monitoring of lung cancer and pulmonary fibrosis.
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15 May 2026

Hidden Immune Gene Defect May Explain Kaposi Sarcoma Susceptibility

15 May 2026

Gene Panel Shows Promise for Predicting Chemotherapy Response in TNBC

14 May 2026

Large-Scale Genomic Surveillance Tracks Resistant Bacteria Across European Hospitals

14 May 2026

Realistic Mock Samples Aim to Speed Cervical Cancer Test Development

14 May 2026

Point-of-Care Testing Enhances Health Literacy and Self-Management in Chronic Disease

14 May 2026

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IImage: The landmark partnership is designed to reshape how health systems identify, risk-stratify, and manage chronic kidney disease (photo courtesy of 123RF)

Partnership Aims to Bring Risk-Guided CKD Care to Health Systems

Chronic kidney disease (CKD) places a substantial clinical and financial burden on the United States. Read more
15 May 2026 | Industry

Image: Roche’s CE-Marked Elecsys pTau217 blood test is a single‑assay blood test measures phosphorylated tau 217, an indicator of amyloid pathology and a hallmark of Alzheimer’s disease (image credit: Shutterstock)

Blood-Based Alzheimer’s Test Gains CE Mark for Amyloid Pathology Detection

Alzheimer’s disease is the most common cause of dementia, yet confirmatory testing remains invasive and hard to access. Read more
14 May 2026 | Clinical Chem.

Image: The findings suggest IGRA control responses offer a scalable measure of immune function from a widely used clinical assay (image credit: Adobe Stock)

Routine TB Screening Test May Reveal Immune Aging and Mortality Risk

Immune aging is associated with weaker responses to vaccination, greater risks of infection, and higher levels of inflammation. Read more
14 May 2026 | Immunology

Synopsis: TMPRSS2-ERG confers resistance of prostate cancer to antiandrogens (Sekar, A., Selvadurai, B.R., Chatterjee, R. et al. EMBO Molecular Medicine (2026). doi.org/10.1038/s44321-026-00423-7)

Molecular Marker Identifies Hormone Therapy Resistance Pathway in Prostate Cancer

Most prostate cancers depend on androgen signaling, making hormone suppression or blockade a central treatment strategy. Read more
14 May 2026 | Molecular Diagnostics

mage: Combining genetic factors with markers of biological ageing could enable a simple blood test to identify dementia risk before symptoms emerge (photo courtesy of Shutterstock)

Blood-Based “Ageing Clock” Helps Predict Dementia Risk and Earlier Onset

Dementia imposes a growing health burden, affecting an estimated 982,000 people in the UK, with cases projected to reach 1. Read more
14 May 2026 | Molecular Diagnostics

Image: Processed on IDS’ random-access automation platforms, the comprehensive portfolio enables direct ChLIA measurement of total testosterone, SHBG, and free testosterone (photo courtesy of Revvity)

FDA-Cleared Assay Enables Comprehensive Automated Testosterone Testing

Accurate evaluation of androgen status often requires concordant measurement of total testosterone, free testosterone, and sex hormone‑binding globulin. Read more
13 May 2026 | Clinical Chem.

Image: Pleiotropic synapse-related genes expressed in peripheral leukocytes of patients with major depressive disorder. The figure summarizes molecular pathways shared between peripheral immune alterations and central synaptic processes in major depressive disorder (Adri, A.S., Nóbile, A.L., de Albuquerque, D.G. et al. Scientific Reports (2026). https://doi.org/10.1038/s41598-026-39284-y)

Gene Signature Shows Promise for Depression Biomarker Testing

Major depressive disorder (MDD) exerts systemic effects that extend beyond mental health, reflecting interplay between the nervous and immune systems. Read more
13 May 2026 | BioResearch

Image: IsoPSA is a blood-based test designed to aid in prostate biopsy decision‑making for men aged 50 years and older with elevated PSA levels (image credit: Shutterstock)

Blood Test Refines Biopsy Decisions in Prostate Cancer

Prostate biopsy decisions remain challenging, with many men undergoing invasive procedures that ultimately yield negative results. Read more
13 May 2026 | Molecular Diagnostics

Image: The platform is built on a foundation model of tumor and immune biology, integrating genomic, transcriptomic, immune, and clinical signals to generate biologically grounded insights (image credit: 123RF)

AI-Driven Tumor Profiling Initiative Targets Precision Therapy Development

Japan faces a significant oncology need, driving efforts to generate clinically relevant data for precision therapies. Read more
13 May 2026 | BioResearch

Image: Schematic overview of the GlycoHBF workflow, from collection of 15 body fluid types to standardized processing and dual-layer proteomic and glycoproteomic profiling (Yong Zhang, CC BY-NC-ND)

Researchers Map Protein and Glycosylation Across 15 Human Body Fluids

Proteins circulating in human body fluids carry valuable signals for health assessment and disease detection. Read more
13 May 2026 | BioResearch

Image: The addition of pTau 217 complements blood-based approaches for clinical decision-making in neurology workflows. The fully automated format supports scalability on the LUMIPULSE G platform (photo courtesty of Shutterstock)

CE-Marked Blood Biomarker Test Advances Automated Alzheimer’s Diagnostics

Specialized care settings frequently evaluate patients aged 50 years and older who present with signs and symptoms of cognitive decline to determine whether amyloid pathology linked to Alzheimer’s disease is present. Read more
13 May 2026 | Clinical Chem.

Image: Graphical Abstract (Jiaming Li, et al. Cell, 2026. doi:10.1016/j.cell.2026.04.025)

Digital Aging Twin Quantifies Biological Aging Across Multiple Organ Systems

Chronological age often fails to capture the wide variability in physiological decline among adults, limiting risk stratification and long-term monitoring. Read more
13 May 2026 | Molecular Diagnostics

Image: Tuberculosis is a leading cause of death among people living with HIV, yet hospital diagnosis remains difficult because symptoms are often non-specific and many patients cannot produce sputum (image credit:123RF)

Molecular Urine and Stool Tests Do Not Improve Early TB Treatment in Hospitalized HIV Patients

Tuberculosis is the leading cause of death among people living with HIV, and diagnosis in hospital settings remains difficult. Read more
13 May 2026 | Microbiology

Image: The findings point to the feasibility of a quick, noninvasive urine-based approach to support earlier decision-making in multiple psychiatric conditions (photo credit: Shutterstock)

Noninvasive Urine Test May Support Earlier Diagnosis of Psychiatric Disorders

Delays in diagnosing serious psychiatric conditions can leave patients without timely support and complicate treatment planning. Read more
12 May 2026 | Clinical Chem.

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Clinical Chemistry

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At-Home Blood and Cognitive Tests Support Dementia Risk Stratification

Dementia places a substantial burden on patients and health systems, and identifying individuals at elevated risk remains difficult at scale. In the UK, almost a million people are estimated to be living... Read more

Image: The dSAA method partitions a patient’s cerebrospinal fluid into nanoliter-scale compartments and digitally counts the number of TDP-43 protein “seeds” present under a microscope (image credit: Shutterstock)

Ultrasensitive Test Detects Key Biomarker of Frontotemporal Dementia Subtype

Dementia affects more than 57 million people worldwide and is projected to nearly double within two decades, straining health systems and families. While biomarkers now enable accurate identification of... Read more

Routine Blood Tests Years Before Pregnancy Could Identify Preeclampsia Risk

High blood pressure during pregnancy is common and can progress to pre-eclampsia, making close monitoring at antenatal visits essential. However, most risk assessment begins only after pregnancy has started.... Read more

Blood Test Detects Testicular Cancer Missed by Standard Markers

Testicular cancer most often affects adolescents and young adults and is highly treatable when found early. Diagnosis can be difficult when tumors do not produce sufficient levels of standard blood-based... Read more

Molecular Diagnostics

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Image: The schematic diagram links key MASLD, MASH, and MASLD-HCC molecular drivers to emerging multi‑omics biomarkers and therapeutic modalities, highlighting the current barriers in clinical translation and strategic solutions aimed at refined risk stratification and personalized medicine (Photo courtesy of ©Science China Press)

Emerging Biomarkers Advance Early Detection of MASLD and Liver Cancer Risk

Metabolic dysfunction-associated steatotic liver disease (MASLD) affects about 30% of people worldwide and can advance to metabolic dysfunction-associated steatohepatitis (MASH), fibrosis, cirrhosis, and... Read more

Patented Isothermal Amplification Chemistry Advances Decentralized Testing

Molecular diagnostics offer high sensitivity for pathogen detection but typically rely on thermal cycling and specialized instruments, limiting their use outside centralized laboratories.... Read more

$Image: Unlike standard tests that detect bacteria directly, host-response assays measure the body\'s immune response, potentially enabling earlier infection detection and risk identification (image credit: Adobe Stock)$

Finger-Prick Blood Test Aids Early Tuberculosis Detection and Risk Stratification

Household contacts of people with tuberculosis face an estimated 2% risk of developing disease, yet most are asymptomatic at the time of screening. Early-stage cases are often missed because symptom checks... Read more

Image: MyProstateScore2.0 – Active Surveillance Visual Abstract (Jeffrey J. Tosoian et al, Journal of Urology (2026) DOI: 10.1097/ju.0000000000005095)

Urine Test Beats MRI in Identifying Prostate Cancer Upgrading During Active Surveillance

Active surveillance is common for men with low-risk prostate cancer, yet deciding when to repeat biopsy remains challenging. Prostate-specific antigen (PSA) testing and magnetic resonance imaging (MRI)... Read more

Hematology

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Image: Graphical abstract (Waclawiczek A, Leppä AM, Renders S, et al. Cell Stem Cell, 2026. doi:10.1016/j.stem.2026.04.012)

Stem Cell Biomarkers May Guide Precision Treatment in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is an aggressive blood cancer that most often affects older adults and still carries a poor prognosis despite therapeutic advances. Venetoclax-based regimens have improved... Read more

Advanced CBC-Derived Indices Integrated into Hematology Platforms

Diatron, a STRATEC brand, has introduced six advanced hematological indices on its Aquila, Aquarius 3, and Abacus 5 hematology analyzers. The new Research Use Only (RUO) indices include Neutrophil-to-Lymphocyte... Read more

Blood Test Enables Early Detection of Multiple Myeloma Relapse

Bone marrow biopsies remain central to diagnosing and monitoring multiple myeloma, yet the procedure is painful, invasive, and often repeated over time. Older patients—who represent most new cases—can... Read more

Single Assay Enables Rapid HLA and ABO Genotyping for Transplant Matching

CareDx (Brisbane, CA, USA) has introduced AlloSeq Nano, a nanopore‑based HLA (human leukocyte antigen) and ABO genotyping solution unveiled at the European Federation for Immunogenetics (EFI) Conference 2026.... Read more

Immunology

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Biomarkers and Molecular Testing Advance Precision Allergy Care

Allergic diseases often present with similar symptoms but can be driven by distinct biological mechanisms, making standardized care inefficient for many patients. Historically, individuals with pollen... Read more

Image: Schematic of Mpox diagnostic methods.(A) Artificial intelligence (AI)-enhanced image classification can be leveraged to classify lesions concerning for Mpox, particularly in low resource settings where specialists (i.e., infectious disease specialists or dermatologists) are not available. (B) Clinical specimens (including nasal swabs, lesion swabs, or serum samples) can be used for molecular or biochemical confirmation of Mpox infection. (C) Rapidly, field-deployable devices or assays can be developed using various strategies(Mpox) diagnostic methods (Yilgic D, Ergonul O, Tasoglu S. Mpox diagnosis at POC. Trends in Biotechnology. DOI: 0.1016/j.tibtech.2025.04.015)

Point-of-Care Tests Could Expand Access to Mpox Diagnosis

Mpox outbreaks in non-endemic regions have underscored the need for rapid, accessible diagnostics to limit transmission. Polymerase chain reaction (PCR) remains the clinical reference, yet it depends on... Read more

Image: Graphical abstract (Turano PS, Akbulut E, Dewald HK, et al. Cell Reports (2026). DOI: 10.1016/j.celrep.2025.116795)

T-Cell Senescence Profiling May Predict CAR T Responses

Chimeric antigen receptor (CAR) T-cell therapy can deliver striking, durable remissions, yet many patients experience minimal or no benefit. The quality of patient-derived cytotoxic T lymphocytes used... Read more

Finger-Prick Lateral Flow Test Detects Sepsis Biomarkers at Point of Care

Sepsis remains a time-critical condition in which rapid risk assessment is often hindered by reliance on centralized laboratory testing. The global burden is substantial, with an estimated 166 million... Read more

Microbiology

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Image: Biosensor for tuberculosis detection (photo courtesy of UPV)

Rapid Antigen Biosensor Detects Active Tuberculosis in One Hour

Tuberculosis remains a major global health challenge and continues to drive significant morbidity and mortality. The World Health Organization’s 2024 global report cites it as the leading cause of death... Read more

Image: Graphical abstract (Qin, Y. et al., Cell Rep Med 7: 102761 (2026). DOI: 10.1016/j.xcrm.2026.102761)

Oral–Gut Microbiome Signatures Identify Early Gastric Cancer

Early detection of gastric cancer could be advanced by scalable screening strategies using minimally invasive sampling. Saliva collection is noninvasive and cost-effective, supporting wider adoption... Read more

Image: Magnetic field-enhanced alignment and detection of hemozoin in lysed infected red blood cells using polarizing microscopy (photo courtesy of Dickson Mwenda Kinyua, Kirinyaga University)

Label-Free Microscopy Method Enables Faster, Quantitative Detection of Malaria

Microscopy of blood smears remains a cornerstone for malaria diagnosis but can be slow, stain-dependent, and operator intensive. With more than 200 million infections and over 600,000 deaths annually,... Read more

Gut Microbiome Test Predicts Melanoma Recurrence After Surgery

Melanoma remains prone to relapse even after surgery and adjuvant immunotherapy, with 25% to 40% of patients experiencing recurrence. Clinicians lack reliable pre-treatment indicators to identify those... Read more

Pathology

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FDA Clears AI Digital Pathology Tool for Breast Cancer Risk Stratification

Risk assessment at diagnosis is central to guiding therapy for early-stage, hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) invasive breast cancer, where overtreatment... Read more

Image: Tissue sample spatial analysis (on left) and standard H&E image (on right) (Photo courtesy of QIMR Berghofer Medical Research Institute)

New AI Tool Reveals Hidden Genetic Signals in Routine H&E Slides

Pathologists worldwide rely on hematoxylin and eosin (H&E) slides to examine tissue architecture, yet these stains do not reveal the underlying molecular activity that often drives disease.... Read more

Image: SPARK overview, data structure and study design (Trost, F., Zhang, B., Aring, I. et al. https://doi.org/10.1038/s41591-026-04357-y)

AI System Analyzes Routine Pathology Slides to Predict Cancer Outcomes

The digital transformation of pathology is expanding how cancers are evaluated in routine practice. Artificial intelligence (AI) is increasingly applied to routinely collected histological tissue sections,... Read more

New Tissue Mapping Approach Identifies High-Risk Form of Diabetic Kidney Disease

Diabetic kidney disease is a leading cause of chronic kidney disease and end-stage kidney disease, affecting 20%–40% of people with diabetes and more than 107 million individuals worldwide as of 2021.... Read more

Technology

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Fully Automated Sample-to-Insight Workflow Advances Latent TB Testing

Latent tuberculosis remains a substantial testing workload for clinical laboratories as screening programs expand. Despite this growth, only about 40% of testing has shifted from traditional skin tests... Read more

Tumor-on-a-Chip Platform Models Pancreatic Cancer Treatment Response

Pancreatic cancer remains one of the hardest malignancies to treat because tumors are embedded within a dense microenvironment that shapes growth and therapy response. Standard laboratory models often... Read more

New Platform Captures Extracellular Vesicles for Early Cancer Detection

Early diagnosis remains the most effective way to reduce cancer mortality, yet many screening tools miss disease at its earliest stages. Biomarkers shed by tumors into blood and other fluids can be scarce... Read more

Microfluidic Single-Cell Assay Predicts Breast Cancer Risk

Risk stratification for breast cancer remains imprecise, as population-based models and breast density can over- or underestimate individual risk, potentially leading to over- or under-screening.... Read more

Industry

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Roche to Acquire PathAI for Up to $1.05 Billion to Strengthen AI Diagnostics Portfolio

Roche has entered into a definitive merger agreement to acquire PathAI, a company focused on digital pathology and artificial intelligence for pathology laboratories and the biopharma industry.... Read more

FDA Clears Blood-Based Companion Diagnostic for Advanced Breast Cancer Therapy

Endocrine therapy resistance remains a significant challenge in estrogen receptor–positive, human epidermal growth factor receptor 2–negative (HER2-) advanced breast cancer, where tumor evolution can limit... Read more

CareDx Expands Precision Oncology Portfolio with Naveris Acquisition

CareDx Inc. (Brisbane, CA, USA), a precision medicine company advancing clinically differentiated, high-value healthcare solutions for transplant patients and caregivers, has entered a definitive agreement... Read more

Thermo Fisher Scientific to Sell Microbiology Business to Astorg

Thermo Fisher Scientific has signed a definitive agreement to sell its microbiology business to Astorg for approximately $1.075 billion, comprising cash and a $50 million seller note. Announced on April... Read more

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