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Image: The study found rural and nonrural patients have similar follow-up times after positive stool-based DNA tests (Photo courtesy of 123RF)

Stool-Based DNA Testing Leads to Timely Colonoscopy

Colorectal cancer (CRC) remains a leading cause of cancer deaths in the US, yet many patients delay colonoscopy due to hesitancy and long wait times. Read more
15 Oct 2025 | Molecular Diagnostics
Image: The Kidney Klinrisk Algorithm is the first CE-marked AI-based risk stratification tool for assessing progressive kidney function decline (Photo courtesy of Roche)

AI Algorithm Assesses Progressive Decline in Kidney Function

Chronic kidney disease (CKD) affects more than 700 million people worldwide and remains a major global health challenge. Read more
15 Oct 2025 | Technology
Image: Label-free multiphoton microscopy and deep learning can be used in combination to classify pancreatic neuroendocrine neoplasms with high accuracy (Photo courtesy of N. Daigle/University of Arizona)

High-Accuracy Tumor Detection Method Offers Real-Time Surgical Guidance

Pancreatic neuroendocrine neoplasms (PNENs) are rare cancers that affect hormone-producing cells in the pancreas. Read more
15 Oct 2025 | Pathology
Image: The new tool could have direct implications for patient diagnoses and care worldwide (Photo courtesy of Texas Children’s Hospital)

Groundbreaking Tool Improves Genetic Testing Accuracy

Genetic testing plays a crucial role in diagnosing disease, but its accuracy depends heavily on understanding how common certain genetic variants are across populations. Read more
14 Oct 2025 | Molecular Diagnostics
Image: The collaboration aims to improve access to Hb variant testing with the Gazelle POC diagnostic platform (Photo courtesy of Hemex Health)

Terumo BCT and Hemex Health Collaborate to Improve Access to Testing for Hemoglobin Disorders

Millions of people worldwide living with sickle cell disease and other hemoglobin disorders experience delayed diagnosis and limited access to effective care, particularly in regions where testing is scarce. Read more
14 Oct 2025 | Industry
Image: The CloneSeq-SV approach can allow researchers to study how cells within high-grade serous ovarian cancer change over time (Photo courtesy of MSK)

Blood Test Tracks Treatment Resistance in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is often diagnosed at an advanced stage because it spreads microscopically throughout the abdomen, and although initial surgery and chemotherapy can work, most advanced cases eventually recur. Read more
14 Oct 2025 | Immunology
Image: The potential biomarker could identify existing tissue damage, long-term immune activation and complications following COVID-19 (Photo courtesy of 123RF)

Biomarker Blood Test Could Predict Development of Long COVID

Long COVID continues to challenge scientists and clinicians with its complex and poorly understood symptoms that can persist long after an acute SARS-CoV-2 infection. Read more
13 Oct 2025 | Molecular Diagnostics
Image: The DOLPHIN AI tool has been developed by senior author Jun Ding and first author Kailu Song (Photo courtesy of McGill University)

AI Tool Detects Hidden Warning Signs of Disease Inside Single Cells

Detecting early signs of disease at the cellular level remains a major challenge in medicine. Subtle molecular changes often precede visible symptoms, yet these early indicators are difficult to detect with current technologies. Read more
13 Oct 2025 | Pathology
Image: Breast biopsy photomicrograph of ductal carcinoma in situ (DCIS)—The study’s findings could help refine treatment strategies for women with DCIS or LCIS (Photo courtesy of Shutterstock)

Polygenic Risk Score Blood Test Predicts Future Breast Cancer

Breast cancer remains the most common cancer among women, accounting for over 15% of all new cancer diagnoses in the United States. Read more
13 Oct 2025 | Molecular Diagnostics
Image: Researcher Sudhaunsh Deshpande holding the molecularly imprinted polymer-based biosensor (Photo courtesy of University of Liverpool)

AI-Powered Blood Tests Enable Early Detection of Alzheimer’s Disease

Alzheimer’s disease, the most common form of dementia, affects more than 55 million people globally. Early diagnosis is critical for managing symptoms and slowing progression, yet current testing methods rely on costly, complex lab procedures that are often unavailable in local clinics or developing countries. Read more
10 Oct 2025 | Molecular Diagnostics
Image: Revolutionizing early cancer detection with at-home technology (Photo courtesy of Adobe Stock)

Simple Urine Test Could Illuminate Hidden Tumors for Early Cancer Diagnosis

Early detection is critical in the fight against cancer, yet most screening methods remain invasive, expensive, or limited to specific cancer types. Read more
10 Oct 2025 | Molecular Diagnostics
Image: The MaGNet platform zooming in on one section of a mouse mammary gland’s ductal tree (Photo courtesy of Dos Santos lab/CSHL)

Automated Tool Detects Early Warning Signs of Breast Cancer

Branching is a vital biological process that enables organs like the lungs, kidneys, and breasts to perform complex functions. Read more
10 Oct 2025 | Pathology
Image: Impaired vascular function in patients with chronic kidney disease (A K Grotle et al., Am J Physiol Renal Physiol (2025). DOI: 10.1152/ajprenal.00158.2025)

Kidney Disease Blood Marker Could Also Identify Cardiovascular Problems

Chronic kidney disease (CKD) affects millions worldwide and is strongly linked to cardiovascular complications rather than kidney failure itself. Read more
09 Oct 2025 | Molecular Diagnostics
Image: A conceptual and flexible integration of spatial datasets across multiple length scales and data modalities in Giotto Suite (Photo courtesy of Chen, Chávez-Fuentes, et al., Nature Methods; DOI: 10.1038/s41592-025-02817-w)

New Software Tool Improves Analysis of Complex Spatial Data from Tissues

Advances in spatial omics have enabled scientists to map the distribution of RNA and proteins within intact tissues, offering powerful insights into how cells behave and interact in both health and disease. Read more
09 Oct 2025 | Pathology

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Clinical Chemistry

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Portable Raman Spectroscopy Offers Cost-Effective Kidney Disease Diagnosis at POC...
Gold Nanoparticles to Improve Accuracy of Ovarian Cancer Diagnosis
Simultaneous Cell Isolation Technology Improves Cancer Diagnostic Accuracy
Image: Schematic diagram of esophageal cancer cell identification research process (Photo courtesy of GE Dianlong)

VOCs Show Promise for Early Multi-Cancer Detection

Early cancer detection is critical to improving survival rates, but most current screening methods focus on individual cancer types and often involve invasive procedures. This makes it difficult to identify... Read more

Molecular Diagnostics

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Automated Molecular Tests Detect Bacterial Pathogens Causing Infectious Gastroen...
Novel Test Offers New Accuracy Level in Heart Attack Diagnosis
Blood Test Detects Rheumatoid Arthritis in At-Risk Individuals Before Symptoms
Image: LungCanSeek demonstrated an overall sensitivity of 83.5% and specificity of 90.3% in detecting lung cancer (Photo courtesy of AdobeStock)

New Blood Test Offers Affordable and Accurate Early Detection of Lung Cancer

Lung cancer remains the leading cause of cancer-related deaths worldwide, largely because most cases are diagnosed at advanced stages when treatment options are limited. Early detection significantly improves... Read more

Hematology

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Pioneering Model Measures Radiation Exposure in Blood for Precise Cancer Treatments...
Platelets Could Improve Early and Minimally Invasive Detection of Cancer
Portable and Disposable Device Obtains Platelet-Rich Plasma Without Complex Equi...
Image: New evidence shows viscoelastic testing can improve assessment of blood clotting during postpartum hemorrhage (Photo courtesy of 123RF)

Viscoelastic Testing Could Improve Treatment of Maternal Hemorrhage

Postpartum hemorrhage, severe bleeding after childbirth, remains one of the leading causes of maternal mortality worldwide, yet many of these deaths are preventable. Standard care can be hindered by delays... Read more

Immunology

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Blood-Based Immune Cell Signatures Could Guide Treatment Decisions for Critically...
Novel Tool Predicts Most Effective Multiple Sclerosis Medication for Patients
Companion Diagnostic Test for CRC Patients Identifies Eligible Treatment Populat...
Image: The tool enables scientists to track real-time fluctuations in T cell function with unprecedented speed and precision (Photo courtesy of Shutterstock)

Luminescent Probe Measures Immune Cell Activity in Real Time

The human immune system plays a vital role in defending against disease, but its activity must be precisely monitored to ensure effective treatment in cancer therapy, autoimmune disorders, and organ transplants.... Read more

Microbiology

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Rapid Sepsis Diagnostic Device to Enable Personalized Critical Care for ICU Patients...
Microfluidic Platform Assesses Neutrophil Function in Sepsis Patients
New Diagnostic Method Confirms Sepsis Infections Earlier
Image: Sugar fingerprints open new possibilities for faster and more reliable diagnosis of fungal infections (Photo courtesy of 123RF)

Fast Noninvasive Bedside Test Uses Sugar Fingerprint to Detect Fungal Infections

Candida bloodstream infections are a growing global health threat, causing an estimated 6 million cases and 3.8 million deaths annually. Hospitals are particularly vulnerable, as weakened patients after... Read more

Pathology

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New Tool Could Revolutionize Acute Leukemia Diagnosis
New Microscope Promises to Speed Up Medical Diagnostics
ESR Testing Breakthrough Extends Blood Sample Stability from 4 to 28 Hours
Image: Overview of the pathology image characterization tool with uncertainty-aware rapid evaluations (J Zhao et al., Nat Commun (2025). DOI: 10.1038/s41467-025-64249-6)

AI Tool Helps Surgeons Distinguish Aggressive Glioblastoma from Other Brain Cancers in Real-Time

Accurately distinguishing between brain tumors during surgery is one of the toughest diagnostic challenges in neuro-oncology. Glioblastoma, the most common and aggressive brain tumor, often appears similar... Read more

Technology

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3D Micro-Printed Sensors to Advance On-Chip Biosensing for Early Disease Detection...
Hybrid Pipette Combines Manual Control with Fast Electronic Aliquoting
Coral-Inspired Capsule Samples Hidden Bacteria from Small Intestine
Image: The technology enables infected individuals to detect an infection within minutes, without requiring a laboratory, electricity, or medical personnel (Raschig, M. et al., ACS Central Science (2025). DOI: 10.1021/acscentsci.5c01179)

Taste-Based Influenza Test Could Replace Nasal Swabs with Chewing Gum

Influenza is one of the most dangerous infectious diseases worldwide, claiming around half a million lives each year. What makes it particularly insidious is that flu viruses are contagious even before... Read more

Industry

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GSI Group Acquires Blood Processing Equipment Manufacturer GenesisBPS
ELITech and Hitachi High-Tech to Develop Automated PCR Testing System for Infectious...
Lumiquick Acquires Aoxre to Expand Global IVD and Research Capabilities
Image: The collaboration supports clinical validation and regulatory submissions of the new T1D 4-plex assay on Revvity’s GSP instrument (Photo courtesy of Revvity)

Revvity and Sanofi Collaborate on Program to Revolutionize Early Detection of Type 1 Diabetes

Type 1 diabetes (T1D) is a lifelong autoimmune condition in which the immune system destroys the pancreas’s insulin-producing beta cells, leading to dependence on insulin therapy. Early detection is critical... Read more

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