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image: Ataraxis Breast CTX combines H&E pathology slides with clinical data to generate patient-specific prognostic and predictive outputs (photo courtesy of Ataraxis AI)

AI Tool Predicts Patient-Specific Chemotherapy Benefit in Breast Cancer

Selecting adjuvant chemotherapy for early-stage breast cancer is typically guided by recurrence risk and population-level averages rather than patient-specific benefit. Read more
01 Apr 2026 | Pathology
Image: The EvORanker AI algorithm narrows thousands of candidate genes to the most probable disease-causing target (photo credit: 123RF)

New AI Tool Improves Detection of Genetic Causes in Rare Disorders

Families affected by rare diseases often endure years of inconclusive testing and fragmented referrals before a definitive diagnosis. Read more
01 Apr 2026 | Molecular Diagnostics
image: The new findings provide critical genetic information to understand how SDSE spreads, evolves, and causes infection, with insights intended to support diagnosis, infection control, and vaccine planning (photo credit: 123RF)

Genomic Analysis Links Emerging Streptococcal Strains to Specific Infections

Streptococcus dysgalactiae subspecies equisimilis (SDSE) infections are increasing worldwide and include variants that may lead to severe disease. Read more
01 Apr 2026 | Microbiology
Image: The collaboration focuses on verified automation methods for Takara Bio USA’s SMART-Seq library preparation kits on Hamilton’s Microlab STAR Liquid Handling Systems (photo courtesy of Hamilton Company)

Takara Bio USA and Hamilton Partner Partner to Automate NGS Library Preparation

Takara Bio USA, Inc. (San Jose, CA, USA), a wholly owned subsidiary of Takara Bio Inc., and Hamilton Company (Reno, NV, USA) announced a development and co-marketing agreement to deliver integrated, automated next-generation sequencing (NGS) library preparation workflows to laboratories worldwide. Read more
01 Apr 2026 | Industry
Image: The direct-from-urine rapid method can identify an effective antibiotic in an average of 5.85 hours (photo courtesy of Shutterstock)

Rapid Urine Test Speeds Antibiotic Selection for UTIs

Urinary tract infections are a common reason for antibiotic prescribing and have led to more than 800,000 hospital admissions across England in the past five years, according to National Health Service data. Read more
31 Mar 2026 | Microbiology
Image: Study cohorts, deep learning system architecture, and performance evaluation on TAILORx-Test (Shamai G, Cohen S, Binenbaum Y et al., Lancet Oncology, 2026; . DOI: 10.1016/s1470-2045(25)00727-2)

AI-Based Pathology Model Guides Chemotherapy Decisions in Breast Cancer

Selecting adjuvant chemotherapy for early-stage breast cancer remains a difficult decision because only a subset benefits and many undergo toxicity without gain. Read more
31 Mar 2026 | Pathology
Image: The partnership combines Lunit’s platform-agnostic AI pathology algorithms with CellCarta’s global CDx development and laboratory execution (photo courtesy of Lunit)

Lunit and CellCarta Collaborate to Expand AI Pathology in CDx Development

Lunit (Seoul, South Korea), a leading provider of AI for cancer diagnostics and precision oncology, and CellCarta (Montreal, QC, Canada), a global contract research organization (CRO) laboratory serving the biopharmaceutical industry, have announced a strategic partnership. Read more
31 Mar 2026 | Industry
Image: The BiliSeq assay detects cancer-associated genetic mutations in bile duct tissue (photo courtesy of Adobe Stock)

New Molecular Test Boosts Accuracy of Bile Duct Cancer Diagnosis

Bile duct strictures can arise from cancer or benign disease, but their location within ducts connecting the liver, gallbladder, and intestines complicates evaluation. Read more
31 Mar 2026 | Molecular Diagnostics
Image:n6 has introduced icon16, expanding its AutoNorm adaptive amplification to a 16‑well format for laboratories running lower-throughput NGS (photo courtesy of n6)

Adaptive PCR Platform Improves Consistency in Small-Batch NGS Workflows

PCR amplification during next-generation sequencing (NGS) library preparation can introduce variability, often requiring manual quantification and risking over-cycling artifacts. Read more
31 Mar 2026 | Molecular Diagnostics
Image: Graphical Abstract (Huiqian Hu et al., Med 7(3): 100966 (2026). DOI: 10.1016/j.medj.2025.100966)

New AI Tool Enables Rapid Treatment Selection in Pediatric Leukemia

Children with T-cell acute lymphoblastic leukemia face an aggressive disease that remains difficult to treat. Read more
31 Mar 2026 | Technology
Image: Many targeted tumors activate a backup pathway to sustain growth when tyrosine kinase—shown here as strands—is inhibited (Photo courtesy of Massachusetts Institute of Technology)

Researchers Identify Survival Pathway Undermining Targeted Cancer Drugs

  Targeted tyrosine kinase inhibitors are a cornerstone of precision oncology, yet only 40–80% of eligible patients respond. Read more
31 Mar 2026 | BioResearch
Image: The new MultiQ-IT prototype can cool, trap, filter, and redirect over a billion ions simultaneously, dramatically improving dynamic range and signal-to-noise (Photo courtesy of Lori Chertoff/The Rockefeller University)

Breakthrough Mass Spectrometry Design Could Enable Ultra-Low Abundance Detection

Mass spectrometry is central to identifying and quantifying molecules in complex biological samples, but conventional instruments typically analyze ions sequentially, which can limit detection of rare species. Read more
31 Mar 2026 | Technology
Image: Researchers have identified a frequent recessive disorder linked to the RNU2-2 gene that underlies difficult-to-control seizures in infancy (photo courtesy of Shutterstock)

Genetic Cause Identified for Severe Infant Epilepsy

Severe early-onset epilepsy and neurodevelopmental delay leave many families without clear answers, and antiseizure medications often fail to fully control symptoms. Read more
31 Mar 2026 | BioResearch
Image: Schematic illustration of the MetaRing platform for detecting paclitaxel treatment sensitivity in breast cancer (Photo courtesy of HUANG Guangyao)

Rapid Biosensor Detects Drug Sensitivity in Breast Tumors

Chemotherapy selection for breast cancer is challenged by heterogeneous tumor responses. Conventional chemosensitivity assays can be slow, require large sample volumes, and struggle with complex biological matrices, limiting same-day decision-making. Read more
30 Mar 2026 | Technology

Channels

Clinical Chemistry

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Study Shows Dual Biomarkers Improve Accuracy of Alzheimer’s Detection
Blood-Based Screening Test Targets Early Detection of Colorectal Cancer
Automated NfL Assay Supports Monitoring of Neurological Disorders
Image: The assays run on the cobas i 601 analyzer as part of the cobas Mass Spec solution (photo courtesy of Roche)

New CLIA Status Brings Mass Spectrometry Steroid Testing to Routine Labs

Steroid hormone measurement is a core application of clinical mass spectrometry, which is widely regarded as a diagnostic gold standard. Access to these high-specificity methods has often been constrained... Read more

Molecular Diagnostics

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Portable Test Uses CRISPR to Rapidly Identify STIs and Resistance Markers
Plasma ctDNA Testing Predicts Breast Cancer Recurrence After Neoadjuvant Therapy
New Respiratory Panel Expands Pathogen Detection to 25 Targets
Image: The assay serves as an adjunctive tool in evaluating patients suspected of B-cell lymphoproliferative disorders (photo courtesy of Shutterstock)

First IVDR‑Certified IGH Clonality Assay Supports Diagnosis of B-Cell Malignancies

Accurate identification of clonal immunoglobulin heavy chain (IGH) gene rearrangements is central to evaluating suspected B-cell lymphoproliferative disorders, where a single B-cell clone yields a defining... Read more

Hematology

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New Guidelines Aim to Improve AL Amyloidosis Diagnosis
Fast and Easy Test Could Revolutionize Blood Transfusions
Automated Hemostasis System Helps Labs of All Sizes Optimize Workflow
Image: Hemex Health’s Gazelle platform is designed to rapidly separate and detect hemoglobin fractions and variants using miniaturized electrophoresis technology (photo courtesy of Hemex Health)

Rapid Cartridge-Based Test Aims to Expand Access to Hemoglobin Disorder Diagnosis

Sickle cell disease and beta thalassemia are hemoglobin disorders that often require referral to specialized laboratories for definitive diagnosis, delaying results for patients and clinicians.... Read more

Immunology

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Study Identifies Inflammatory Pathway Driving Immunotherapy Resistance in Bladder...
Microfluidic Chip Detects Cancer Recurrence from Immune Response Signals
Cancer Mutation ‘Fingerprints’ to Improve Prediction of Immunotherapy Response
Image: Accurate immunotherapy selection for esophageal and GEJ carcinomas depends on consistent PD-L1 assessment (credit: Adobe Stock)

FDA Approval Expands Use of PD-L1 Companion Diagnostic in Esophageal and GEJ Carcinomas

Esophageal and gastroesophageal junction carcinomas (GEJ) have a poor prognosis, with approximately 16,250 deaths in the United States in 2025 and a five-year relative survival of 21.9%.... Read more

Microbiology

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Breath Analysis Approach Offers Rapid Detection of Bacterial Infection
Study Highlights Accuracy Gaps in Consumer Gut Microbiome Kits
WHO Recommends Near POC Tests, Tongue Swabs and Sputum Pooling for TB Diagnosis
Image: The guidance recommends easy‑to‑collect tongue swab samples and a cost‑saving sputum pooling strategy for TB and rifampicin‑resistant TB. (photo courtesy of WHO / Enric Catala Contreras)

WHO Endorses Rapid Point-of-Care Testing to Improve TB Detection

Tuberculosis (TB) remains a leading infectious killer, with more than 3,300 deaths and 29,000 new illnesses every day. Diagnostic delays and dependence on centralized laboratory networks continue to impede... Read more

Pathology

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AI-Powered Tool to Transform Dermatopathology Workflow
New Chromogenic Culture Media Enable Rapid Detection of Candida Infections
Novel mcPCR Technology to Transform Testing of Clinical Samples
Image: Study Overview (Steiner, D., Sultan, L., Sullivan, T. et al. Nat Commun 17, 2581 (2026). doi.org/10.1038/s41467-026-70600-2)

Biopsy-Based Gene Test Predicts Recurrence Risk in Lung Adenocarcinoma

Lung cancer is the leading cause of cancer death, killing more people in the United States than breast, prostate, and colon cancers combined. In lung adenocarcinoma (LUAD), tumors that invade nearby blood... Read more

Technology

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Portable Breath Sensor Detects Pneumonia Biomarkers in Minutes
New Electronic Pipette Enhances Workflows with Touchscreen Control
AI Model Outperforms Clinicians in Rare Disease Detection
Image: Screenshots from the GIFT web platform (Photo courtesy of Jacob Dwyer, Michigan Medicine)

Online Tool Supports Family Screening for Inherited Cancer Risk

Genetic test results in oncology often have implications for relatives who may share inherited cancer risk. Many health systems lack structured processes to help patients alert family members, limiting... Read more

Industry

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Co-Diagnostics Agreement Expands Commercial and Distribution Reach in South Asia
Automated MSI Test Gains IVDR Certification to Guide CRC Therapy
New Partnership Brings Alzheimer’s Blood Biomarker Test to Community Screening N...
Image: IDT’s Archer IVD Assay portfolio is built on easy-to-use Anchored Multiplex PCR technology (photo courtesy of IDT)

Integrated DNA Technologies Expands into Clinical Diagnostics

Integrated DNA Technologies (IDT; Coralville, Iowa, USA) has announced the launch of Archer FUSIONPlex-HT Dx and VARIANTPlex-HT Dx. This launch marks the company’s first in vitro diagnostic (IVD) offerings... Read more

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