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In Other News

Image: The acquisition of Reveal Genomics would expand Hologic’s oncology diagnostics portfolio to support treatment decisions for more women with breast cancer.

Hologic to Broaden Breast Cancer Testing Portfolio Through Reveal Genomics Acquisition

Hologic has signed a definitive agreement to acquire precision oncology company Reveal Genomics. Read more
20 Oct 2026 | Industry
Image: The definitive agreement covers Myriad Genetics’ Prenatal Health testing business, including the Prequel, Foresight, SneakPeek, and FirstGene tests. (Photo courtesy of Myriad Genetics)

Myriad Genetics to Sell Prenatal Testing Portfolio to Labcorp

Myriad Genetics has entered into a definitive agreement to sell its Prenatal Health testing business to Labcorp for $210 million. Read more
20 Oct 2026 | Industry
Image Credit: iStock

Managed Care Report Examines Barriers to Breast Cancer Biomarker Testing

A new analysis examines uncertainty around biomarker testing and managed care for advanced breast cancer with ESR1 mutations. Read more
20 Oct 2026 | Industry
Image: Latest trends show that cancer diagnosis is evolving beyond a process focused mainly on medical imaging and microscopic tissue examination toward a more layered approach that incorporates molecular and genomic testing, liquid biopsy, digital pathology, and AI (Image Credit: iStock)

Expanding Screening and Biomarker Testing Drive Cancer Diagnostics Market Growth

New data forecast the cancer diagnostics market to reach USD 41.5B by 2031 at 7.2% CAGR amid growth in IVDs and liquid biopsy Read more
20 Oct 2026 | Industry
Image Credit: 123RF

Molecular Panel Gains WHO Emergency Use Listing to Support Ebola Outbreak Response

WHO grants Emergency Use Listing to a molecular panel for testing Ebola and other high-risk pathogens from whole blood. Read more
20 Oct 2026 | Microbiology
Image: The MyChoice CDx test, currently used as a companion diagnostic in ovarian cancer, will generate the PrGIS score and is being advanced for use in prostate cancer. (Photo courtesy of Myriad Genetics)

Collaboration Advances Genomic Instability Biomarker for Prostate Cancer

A new collaboration aims to advance a prostate cancer genomic instability score for clinical trials and companion diagnostics. Read more
20 Oct 2026 | Industry
IMage: Labcorp will acquire BioReference Health’s 4Kscore Test, an FDA-approved blood test that helps predict the likelihood of aggressive prostate cancer before biopsy. (Photo courtesy of OPKO Health

Labcorp Acquisition to Strengthen Specialty Testing and Prostate Cancer Assessment

Labcorp has entered into an agreement with OPKO Health to acquire select assets of BioReference Health. Read more
20 Oct 2026 | Industry
Image: NeoGenomics selected Indica Labs’ HALO AP platform to eable its digital pathology operations through a scalable, cloud-based framework (Photo courtesy of Indica Labs)

Expanded Partnership Scales AI-Powered Digital Pathology for Oncology

NeoGenomics has expanded its partnership with Indica Labs to scale AI-powered digital pathology across its enterprise. Read more
20 Oct 2026 | Industry
Image: A new pilot rapid test for syphilis from a team led by Penn State researchers integrates two blood tests into one and detects bacteria at very low levels to detect the disease in its earliest stages. (Photo courtesy of Pan Research Lab / Penn State)

New One-Step Syphilis Test Could Enable Earlier Detection and Faster Treatment

A new rapid syphilis test combining treponemal and non-treponemal targets boosts low-titer detection, enabling earlier diagnosis. Read more
19 Oct 2026 | Clinical Chem.
Image Credit: Adobe Stock

Immune Profiling Identifies Early Maternal Autoantibodies Linked to Preterm Birth Risk

A new immune profiling tool identifies maternal autoantibodies tied to preterm birth, allowing earlier risk stratification. Read more
19 Oct 2026 | Immunology
Image: The test combines RNA signals from the tumor-immune microenvironment to predict treatment response, rather than relying on a single marker such as PD-L1 expression.(Image Credit: Adobe Stock)

RNA-Based Test Predicts Immunotherapy Response in Non-Small Cell Lung Cancer

An RNA-based test integrating tumor-immune signals predicts NSCLC immunotherapy response. Read more
19 Oct 2026 | Molecular Diagnostics
Image: Shield is a blood-based CRC screening test that uses methylation partitioning cell-free DNA (mp-cfDNA) technology to detect colorectal cancer-associated alterations (Photo courtesy of Guardant Health, Inc.)

Modeling Study Shows Blood-Based CRC Screening Could Prevent More Deaths Than Stool Tests

New data show a blood-based colorectal cancer screening test boosts adherence and colonoscopy uptake. Read more
19 Oct 2026 | Molecular Diagnostics
Image: Graphical Abstract (M. A. A. Kodydek, M. E. Reyna, A. Kothari, et al., “ IgE Sensitization Patterns of Mothers and Their Offspring in the First Five Years of Life The CHILD Study,” Allergy (2026): 1–11, https://doi.org/10.1111/all.70516)

Longitudinal Blood Testing Reveals Changes in Allergen Sensitization During Childhood

A new study tracked IgE sensitization patterns from infancy to age 5, providing new insight to help guide pediatric care. Read more
19 Oct 2026 | Immunology

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Clinical Chemistry

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Study Evaluates Alzheimer’s Blood Biomarker Across Racial and Ethnic Groups
Blood Protein May Help Identify Treatment-Resistant Psychosis
Electrochemical Biosensor Rapidly Detects Cerebrospinal Fluid Leaks
Image: Overview of available modalities in the MSK-IMPACT cohort (n = 52,236 patients), including longitudinal BMI trajectories, serologic laboratory tests, radiology-derived progression annotations and tumor genomic profiling. Human silhouette created in BioRender. (Castillon, V.J., Xie, A.X., Boscenco, S. et al. Nature Medicine (2026). https://doi.org/10.1038/s41591-026-04689-9)

Multimodal Clinical Data Models Predict Cachexia Risk Across Cancers

Cancer cachexia is a severe wasting syndrome that affects roughly half of patients with cancer and cannot be reversed simply by increasing food intake. It can reduce treatment tolerance, impair quality... Read more

Molecular Diagnostics

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Noninvasive Cervical Test Detects Endometrial Cancer for Triage
Molecular Test Detects Barrett’s Esophagus to Guide Endoscopy Referral
Blood-Based Metagenomic Test Detects Wide Range of Pathogens from Single Sample
Image: Supervised learning facilitates the generation of an STXBP1-specific variant effect predictor, EpiPred. (Jeffrey D. Calhoun et al., Gene-specific machine learning model EpiPred identifies likely pathogenic variants in the epilepsy-related gene STXBP1, Journal of Clinical Investigation (2026). DOI: 10.1172/jci207160)

AI Tool Classifies Pathogenic Variants in Severe Childhood Epilepsy

Developmental and epileptic encephalopathies are rare neurodevelopmental disorders characterized by early-life seizures and significant developmental delays. Genetic testing can identify variants associated... Read more

Hematology

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Handheld Point-of-Care Test Aims to Enable Rapid Coagulation Assessment in Traum...
New Donor Genetic Marker May Help Predict Stem Cell Transplant Success
Updated Ferritin Thresholds Improve Detection of Iron Deficiency
Image: The recommendations include extended molecular testing at diagnosis to identify high-risk mutations and guide care. (Image Credit: Adobe Stock)

New Myelofibrosis Guidelines Recommend Expanded Genetic Testing at Diagnosis

Myelofibrosis is a rare, life-threatening blood cancer affecting up to six per 100,000 people. The disease causes scarring in the bone marrow, limiting the production of healthy blood cells and potentially... Read more

Immunology

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Blood-Based Immune Aging Map Could Help Spot Disease Risk Earlier
Blood-Based Immune Signal Could Reveal Lung Cancer Risk Before Tumors Develop
Prototype Point-of-Care Test Aims to Improve Neonatal Sepsis Diagnosis
Image Credit: iStock

FDA Approval Adds Automated Testing Option for Parvovirus B19 Serology

Human Parvovirus B19 is a highly contagious erythrovirus transmitted mainly through respiratory droplets and close contact. Diagnosis relies on IgM antibodies to detect active infection and IgG antibodies... Read more

Microbiology

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Oral and Lung Microbiome Changes Linked to Severe Long Covid Symptoms
Study Finds Distinct Malaria Parasites Linked to Sickle Cell Trait Protection
Rapid Urine Test Aids Diagnosis of Invasive Aspergillosis
Image: The TriVerity Test System includes a disposable TriVerity cartridge and the Myrna instrument. It measures 29 host mRNAs from blood and uses machine learning to provide bacterial, viral, and illness severity scores in about 30 minutes. (Photo courtesy of Inflammatix)

Rapid Host-Response Test Aims to Predict Corticosteroid Benefit in Sepsis

Sepsis and severe infections are difficult to treat because patients with similar clinical presentations may have very different underlying immune responses. Corticosteroids are commonly used in severe... Read more

Pathology

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Updated Digital Pathology Platform Expands AI Integration for Cancer Diagnosis
AI Histopathology Tool Distinguishes Ewing Sarcoma for Diagnosis
Rapid Mass Spectrometry Test May Aid Glioma Margin Decisions
Image: TissueCypher analyzes protein biomarkers and tissue architecture in biopsy samples to estimate five-year risk of progression to high-grade dysplasia or esophageal adenocarcinoma. (Photo courtesy of Castle Biosciences)

Molecular Testing Refines Barrett’s Esophagus Progression Risk Beyond Biopsy Findings

Barrett’s esophagus is a precancerous condition associated with increased risk of esophageal adenocarcinoma. Routine endoscopic biopsy findings guide surveillance and therapy, but histopathology may not... Read more

Technology

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Laser-Enhanced Assay Boosts Sensitivity for Colorectal Cancer Biomarker Detectio...
New Automation Workflow Streamlines NGS Library Preparation for High-Volume Labs
ADLM Calls for CLIA Updates to Support Safe AI Use in Laboratory Medicine
Image: The laser-based photoacoustic spectroscopy setup consists of a Mid-IR laser equipped with three QCL modules covering wavelengths from 5.6 μm to 12.9 μm, two silver coated mirrors (SCM), a dichroic mirror (DM) with a transmittance of 90%, a thermal power sensor head (PM) to monitor the output laser power, a mechanical chopper (MC) for frequency modulation and a CEPAS-detector with a self-designed swab holder (SH). (Credit: Graunke, T., Scholz, T., Pieniak, M. et al. Scientific Reports (2026). https://doi.org/10.1038/s41598-026-68298-9)

Laser-Based Swab Analysis Shows Promise for Detecting Disease-Linked Odor Patterns

Disease-related changes in volatile organic compounds can alter body odor, producing measurable patterns in exhaled breath and bodily fluids. Current analytical methods can be complex, time-consuming,... Read more

Industry

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Hospital Partnership Advances Clinical Validation of Portable Diagnostic Technol...
Agilent's Acquisition of Proscia to Advance AI-Enabled Digital Pathology Workflo...
Diazyme Expands Chemistry Testing Portfolio With Alfa Wassermann Acquisition
Image Credit: iStock

Global TB Summit Connects Diagnostic Testing With Prevention and Clinical Care

Tuberculosis remains a major global infectious disease challenge despite declining deaths. In 2024, an estimated 10.7 million people worldwide developed the disease and nearly 1.2 million died from it.... Read more

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