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BioResearch

Image: Electron micrograph of adeno-associated viruses (AAVs) (Photo courtesy of Dr. Graham Beards at en.wikipedia).

Computer Models Help to Develop Improved Gene Therapy Vectors

Investigators in the field of gene therapy have used an advanced computer algorithm to predict how different adeno-associated viruses can be combined to form the optimum carriers of therapeutic genetic material. More...
29 Aug 2013
Image: This photomicrograph depicts airway epithelial cells from lung tissue of a COPD patient. The cell nuclei have been stained to reveal IL-33, a type of signaling molecule found at high levels in COPD patients. New research shows that viral infection can induce these cells to proliferate. Release of IL-33 from these cells promotes inflammatory mucus production. These findings provide insight into the mechanisms linking acute infection to chronic inflammatory lung disease (Photo courtesy of Holtzman Lab, Washington University School of Medicine).

Cytokines Induced by Exposure to Airborne Pollutants Drive the Transition from Acute to Chronic Lung Infections

Molecular signaling molecules that link acute viral infections with the development of chronic diseases such as chronic obstructive pulmonary disease have been identified in a mouse model and in human patient samples. More...
28 Aug 2013

Brains Cells May Regenerate After Radiotherapy

Research suggests that neural stem cells are resistant to radiation, and can be woken up to reproduce and generate new cells able to migrate, replace damaged cells, and possibly restore lost function. More...
28 Aug 2013
Image: The PhenX toolkit homepage. Use of PhenX toolkit measures helps researchers understand the relationships between genetics, health, disease, and environment (Photo courtesy of PhenX Toolkit, RTI).

Toolkit Designed to Expand Resources for Genomic Research

Use of a new genotype/phenotype resource should help researchers better determine the links between genetics, disease, health, and the environment. More...
28 Aug 2013
Image: Electron micrograph depicts the rhabdovirus responsible for vesicular stomatitis (VS) in horses, cattle, and pigs. An inactivated rhabdovirus was used in recent studies to destroy leukemia cells (Photo couryesy of the [US] Centers for Disease Control (CDC)).

Nonreplicating Virus Kills Leukemia in Mouse and Culture Models

A biopharmaceutical drug comprising nonreplicating virus particles killed leukemia cells in a mouse leukemia model and in cultures of cells taken from patients with multiple drug resistant forms of the disease. More...
27 Aug 2013
Image: Confocal microscopy images showing the different levels of organization (Photo courtesy of Agency for Science, Technology and Research (A*STAR), Singapore).

Methodic Strategy Developed for 3D Tissue Engineering of Viable Organ Implants

Researchers in Singapore have developed a simple way to organize cells and their microenvironments in hydrogel fibers. More...
27 Aug 2013

Study Finds Bacterial Antigen Critical in Lethal Effects of Infection, Provides Clues for Therapy

A predominant molecular cause underlying lethal forms of infective endocarditis, sepsis, and kidney damage that often result from Staphylococcus aureus infection has been found, as well as indications for prevention and treatment therapies. More...
27 Aug 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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