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Molecular Diagnostics

Image: DNA fragments (yellow) derived from a transplanted heart alongside the patient’s own DNA (blue). A new blood test measures donor DNA fragments and detects acute heart transplant rejection earlier than current methods (Photo courtesy of Erina He, NIH Medical Arts)

Cell-Free DNA Detects Heart Allograft Acute Rejection

After heart transplantation, Endomyocardial biopsy (EMBx) is used to monitor for acute rejection (AR). Unfortunately, EMBx is invasive and its conventional histologic interpretation has limitations. More...
02 Feb 2021
Image: Structure of the CRMP1 protein (Photo courtesy of Wikimedia Commons)

AI-guided Immunoassay Measures Maternal Autoantibodies to Predict Likelihood of Autism Spectrum Disorder

An AI-guided immunoassay that measures maternal autoantibodies accurately predicts the likelihood that a child will develop autism spectrum disorder (ASD). More...
02 Feb 2021
Image: The 20-minute AI analysis detected prostate cancer in urine samples from 76 patients with greater than 99% accuracy (Photo courtesy of Korea Institute of Science and Technology)

A Rapid AI-based Screening Test for Prostate Cancer Biomarkers in Urine

A team of Korean investigators developed a highly accurate rapid technique for diagnosing prostate cancer based on AI (artificial intelligence) monitoring of urinary biomarkers. More...
01 Feb 2021
Image: False-colored electron microscopic image of Bifidobacterium that are one of the major genera of bacteria that make up the gastrointestinal tract and are associated with variants in the lactase gene locus (Photo courtesy of The Keck Science Department of the Claremont Colleges)

ABO Histo-Blood Groups Influence Makeup of Gut Microbiome

Recent genome-wide association studies yielded inconsistent, underpowered and rarely replicated results such that the role of human host genetics as a contributing factor to microbiome assembly and structure remains uncertain. More...
01 Feb 2021
Image: The Cyan ADP flow cytometer (Photo courtesy of Beckman Coulter).

Specific RUNX1 Mutations Cause Different Disease Types

Mutations of the hematopoietic master regulator RUNX1 are associated with acute myeloid leukemia, familial platelet disorder and other hematological malignancies whose phenotypes and prognoses depend upon the class of the RUNX1 mutation. More...
28 Jan 2021
Image: FIT (Fecal Immunochemical Test) is a stool test designed to identify possible signs of bowel disease. It detects minute amounts of blood in feces (fecal occult blood) (Photo courtesy of Alpha Laboratories, United Kingdom)

Study Confirms Performance of Rapid Stool Test for Detection of Colorectal Cancer

A recently published paper confirmed the diagnostic performance of the fecal immunochemical test (FIT) for patients with low-risk symptoms of colorectal cancer. More...
27 Jan 2021
Image: Diagram of asthma (Photo courtesy of Wikimedia Commons)

Monitoring of Urinary Eicosanoids Distinguishes Mild and Severe Asthma

A novel method for diagnosing severe asthma is based on the monitoring of eicosanoid compounds in samples of urine. More...
26 Jan 2021
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Human Immunodeficiency Virus Assay
RealLine HIV Quantitative Kit


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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