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Hematology

Image: A blood transfusion bag typed for A Rh negative (Photo courtesy of Sherry Yates Young).

Sequencing Enables Precise Match for Blood Transfusions

There are more than 300 known red blood cell (RBC) antigens and 33 platelet antigens that differ between individuals. Sensitization to antigens is a serious complication that can occur in prenatal medicine and after blood transfusion, particularly for patients who require multiple transfusions. More...
30 May 2018
Image: A computer-generated image of E. coli (Photo courtesy of Alissa Eckert and Jennifer Oosthuizen / CDC).

Blood Type Linked to Severity of Diarrhea

Enterotoxigenic Escherichia coli are responsible for millions of cases of diarrhea and hundreds of thousands of deaths every year, mainly of young children. It primarily infects people living in or visiting developing countries. More...
29 May 2018
Image: The Early Sepsis Indicator uses the DxH 900 hematology analyzer (Photo courtesy of Beckman Coulter).

Early Sepsis Indicator Alerts Emergency Department Clinicians

Sepsis is an often-deadly condition that affects 26 million people worldwide every year and is increasing at a rate of 1.5% annually. Timely and accurate detection solutions in the acute-care setting are key components to stopping the progression of sepsis, as patients with less severe sepsis can progress to severe sepsis or septic shock within 72 hours. More...
24 May 2018
Image: The HiSeq 4000 Systems leverage innovative patterned flow cell technology to provide rapid, high-performance sequencing (Photo courtesy of Illumina).

Molecular Tests Equivalent to Bone Marrow Analysis for MM

Multiple myeloma (MM) is a hematologic malignancy characterized by a bone marrow infiltration of clonal plasma cells with heterogeneous involvement in many areas of the bone marrow. More...
09 May 2018
Image: The small plastic chip about the size of a credit card that can deliver the same diagnostic information as a bone marrow biopsy but using a simple blood draw instead (Photo courtesy of the University of Kansas).

Chip-Based Blood Test Developed for Multiple Myeloma

The diagnosis of multiple myeloma, a cancer affecting plasma cells, traditionally forces patients to suffer through a painful bone biopsy. Doctors insert a bone-biopsy needle through an incision to get a bone marrow sample or make a larger incision and remove a section of bone via surgery. More...
03 May 2018
Image: The 3D printed devices can capture microscopic images, when attached to a smartphone camera lens (Photo courtesy of Ozcan Research Group/UCLA).

Smartphone Microscopes Transformed into Lab Devices

Mobile phones have facilitated the creation of field-portable, cost-effective imaging and sensing technologies that approach laboratory-grade instrument performance. However, the optical imaging interfaces of mobile phones are not designed for microscopy and produce distortions in imaging microscopic specimens. More...
25 Apr 2018
Image: The Navios clinical flow cytometer (Photo courtesy of Beckman Coulter).

Flow Cytometry Technique Assessed for Signaling Pathways

Platelet aggregation is a key parameter in arterial thrombosis, leading to myocardial infarction or ischemic stroke. Platelets have several receptors sensitive to different stimuli and drugs that modulate aggregation with potential critical clinico-pathological significance. More...
24 Apr 2018
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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