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Immunology

Image: The ARCHITECT B.R.A.H.M.S PCT assay, which is a two-step immunoassay using chemiluminescent microparticle immunoassay (CMIA) technology (Photo courtesy of Abbott Laboratories).

Commercial Fully Automated Procalcitonin Immunoassay Compared

Procalcitonin (PCT), a 13-kDa peptide precursor of calcitonin, has gained widespread acceptance as an early and specific biomarker for the presence of systemic bacterial infection. In particular, PCT monitoring has demonstrated value in guiding antibiotic use for bacterial infections. More...
04 Dec 2018
Image: The automated ELISpot reader allows analyzing both enzymatic and fluorescent (FluoroSpot) based EliSpot assays (Photo courtesy of Autoimmun Diagnostika).

Dengue Virus Specific T-Cell Responses Correlated with Disease Severity

Dengue virus (DENV) is the cause of the most common mosquito-borne viral infection worldwide, and over half of the global population live in areas where there is intense dengue transmission putting them at risk of dengue infection. More...
04 Dec 2018
Image: The IMMULITE 1000 system is a small bench top immunoassay analyzer (Photo courtesy of Siemens Healthcare Diagnostics).

Levels of IgA Nephropathy Associated with Disease Severity

IgA nephropathy (IgAN) is the most common cause of primary glomerulonephritis. IgAN is associated with a poor prognosis, about 20% to 40% of patients with IgAN progress slowly to end-stage renal failure 20 to 25 years after diagnosis. More...
03 Dec 2018
Image: The ALPHA Histoplasma Enzyme Immunoassay (EIA) test kit (Photo courtesy of IMMY).

Diagnostic Accuracy of Histoplasma Urine Antigen Assay Evaluated

Histoplasmosis is an endemic mycosis in many regions of Latin America. In the human immunodeficiency virus (HIV) infected population it manifests as progressive disseminated histoplasmosis (PDH), an entity hard to diagnose since the causative fungi, Histoplasma capsulatum, is slow growing and requires advance biosafety for its handling. More...
29 Nov 2018
Image: The FLEXMAP 3D instrument is an advanced and versatile multiplexing platform. The platform uses both magnetic and non-magnetic microspheres and is capable of simultaneously measuring up to 500 genes or proteins from a small sample (Photo courtesy of Luminex).

Plasma Human Proteins Associated with Acute Pediatric Malaria

Severe malaria caused by Plasmodium falciparum continues to be one of the leading infectious causes of morbidity and mortality in children worldwide. The intimate interaction between the pathophysiology of the human host and the biology of the P. falciparum parasite results in a wide spectrum of disease outcomes in malaria. More...
27 Nov 2018
authorization (Photo courtesy of Chembio Diagnostic Systems).

Ebola Test with Portable Reader Authorized for Emergency Use

Ebola is a rare but deadly virus that causes fever, body aches, and diarrhea, and sometimes bleeding inside and outside the body. As the virus spreads through the body, it damages the immune system and organs. Ultimately, it causes levels of blood-clotting cells to drop. This leads to severe, uncontrollable bleeding and kills up to 90% of people infected. More...
26 Nov 2018
Image: The PicoAMH ELISA test measures the amount of Anti-Müllerian Hormone (AMH) in the blood (Photo courtesy of Ansh Labs).

Diagnostic Test Aids Determination of Menopausal Status

Menopause refers to the time in a woman’s life when she stops having a menstrual period and is no longer fertile. During the menopausal transition, the body's production of estrogen and progesterone, two hormones made by the ovaries, varies greatly. More...
15 Nov 2018
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.

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