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Immunology

Image: Detail of a CaFlux plate and the green fluorescent read-out from activated immune cells (Photo courtesy of Thomas Jefferson University).

New Method Determines Efficacy of Immune Cells

The frequency of pathogen-specific and tumor-specific T cells and their functional activity reflect the effectiveness of immune responses and can serve as useful diagnostic and prognostic indicators. More...
09 Nov 2016
Image: A dipstick immunochromatographic test shows positive results for visceral leishmaniasis with double band at the test and control lines and negative results with bands only at the control line (Photo courtesy of the Indian Institute of Chemical Biology).

Urine-Based Immunoassays Developed for Visceral Leishmaniasis

Visceral Leishmaniasis (VL), a severe parasitic disease, and can be fatal if diagnosis and treatment is delayed and diagnostic tests available for VL such as tissue aspiration are invasive and painful although they are capable of evaluating the treatment response. More...
04 Nov 2016
Image: A diagram of cell cytokine signaling response (Photo courtesy of Stanford University).

Inflammation Test Developed Predicts Cardiovascular Disease

Chronic inflammation, a decline in immune responsiveness, and reduced cardiovascular function are all associated with aging, but the relationships among these phenomena remain unclear. More...
03 Nov 2016
Image: Tests show low levels of blood marker DLK1 were a good predictor of poor fetal growth and complications of pregnancy, and could be used as a NIV prenatal diagnostic (Photo courtesy of Queen Mary University of London).

Potential Maternal Blood Test May Predict Fetal Complications

Researchers have found that the protein DLK1 in blood of pregnant women is required for maternal metabolic adaptations to pregnancy and is associated with fetal growth restriction, and suggested that DLK1 could be used as a prenatal diagnostic marker in a relatively non-invasive test to help determine health of newborns and aid decisions on early elective deliveries. More...
03 Nov 2016
Image: A histopathology of acute cystitis of the bladder (Photo courtesy of the University of Maryland School of Medicine).

Molecular Basis of Acute Cystitis Reveals Susceptibility Genes

Tissue damage is usually regarded as a necessary price to pay for successful elimination of pathogens by the innate immune defense, yet, it is possible to distinguish protective from destructive effects of innate immune activation and selectively attenuate molecular nodes that create pathology. More...
27 Oct 2016
Image: A microscopic view of a typical neuroblastoma with rosette formation (Photo courtesy of Dr. Maria Tsokos, National Cancer Institute).

Neuropeptide May Serve as Biomarker for Neuroblastoma Patients

A study has found the common nerve protein Neuropeptide Y (NPY) to be elevated in the blood of those with an aggressive form of neuroblastoma, suggesting that NPY could serve as biomarker in a prognostic and/or treatment monitoring test, and as a new target for developing a more effective therapeutic drug for this early childhood cancer. More...
26 Oct 2016
Image: A transmission electron microscope (TEM) image of negative-stained, Fortaleza-strain Zika virus (red), isolated from a microcephaly case (Photo courtesy of the NIAID).

Biological Link Found between Zika Infection and Guillain-Barré Syndrome

Guillain-Barré is a very rare but potentially paralyzing disorder of the nervous system that appears days to weeks after infection with viruses or bacteria. More...
19 Oct 2016
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.

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