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Microbiology

Image: A histopathology of active hepatitis C viral infection of the liver (Photo courtesy of California Pacific Medical Center).

Hepatitis C Screening Recommended During Pregnancy

The estimated prevalence of antenatal Hepatitis C (HCV) infection is low in the USA, about 1%-2.5%, although some have suggested that it’s as high as 4% and some have recommended against screening all pregnant women for HCV, citing a lack of data on the cost-effectiveness of universal screening. More...
13 Dec 2017
Image: A colored scanning electron micrograph (SEM) of the periodontal pathogen Porphyromonas gingivalis (Photo courtesy of the Forsyth Institute).

Oral Microbiome Composition Reflects Risk for Esophageal Cancers

Esophageal cancer is the eighth most common cancer and the sixth leading cause of cancer death worldwide. Because the disease is often not discovered until it has reached an advanced stage, five-year survival rates range from about 15% to 25% worldwide. More...
12 Dec 2017

Second Test Helps Prevent Incorrect HIV Diagnosis

The specificity of nucleic acid amplification tests (NAATs) used for early infant diagnosis (EID) of human immunodeficiency virus (HIV) infection is less than 100%, leading some HIV-uninfected infants to be incorrectly identified as HIV-infected. More...
06 Dec 2017
Image: The BACTEC mycobacterial growth indicator tubes (Photo courtesy of Becton, Dickinson and Company).

TB Culture Methods Determine Relapse and Cure

Tuberculosis (TB) kills more people than any other infectious disease, and new regimens are essential. The primary endpoint for confirmatory phase III trials for new regimens is a composite outcome that includes bacteriological treatment failure and relapse. More...
04 Dec 2017
Image: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry apparatus (Photo courtesy of Maciej Kotlinski).

Rapid Detection of Antibiotic Resistance Uses MALDI-TOF MS

A universal phenotypic method has been targeted which would allow easy and rapid antimicrobial susceptibility testing independently of underlying resistance mechanism. More...
30 Nov 2017
Image: The SD BIOLINE Cholera Ag 01/0139 rapid diagnostic test (Photo courtesy of Alere).

Immunochromatographic Rapid Tests Evaluated for Cholera

Cholera remains a significant cause of morbidity and mortality worldwide, resulting in an estimated 2.8 million cases and 91,000 deaths annually. Prompt identification of cholera cases facilitates rapid outbreak responses in the short term, while providing reliable surveillance data to guide long-term policies and interventions. More...
28 Nov 2017
Image: Thin blood film showing ring-form trophozoites of Plasmodium falciparum and a neutrophil containing malaria pigment (Photo courtesy of Hammersmith Hospital).

Leukocyte Counts Change in Liver Phase of Malaria

Both in endemic countries and in imported malaria, changes in total and differential leukocyte count during Plasmodium falciparum infection have been described. More...
22 Nov 2017
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