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Microbiology

Image: A histology of lepromatous leprosy; the bacilli are densely clustered within the cytoplasmic vacuoles of foamy histiocytes (Photo courtesy of Dr. Sampurna Roy, MD).

Severity Biomarker Found for Leprosy and Leishmaniasis

Visceral leishmaniasis (VL) is a systemic, and most severe form of leishmaniasis and soluble CD163 (sCD163) levels can serve as biomarker for disease severity in several inflammatory disorder, including leprosy. More...
14 Apr 2017
Image: The Gram-negative Burkholderia pseudomallei in culture with its characteristic colony shape (Photo courtesy of MMG).

Antigenic Targets Compared for Melioidosis Serodiagnosis

Melioidosis, caused by Burkholderia pseudomallei, is a life-threatening infection endemic in tropical countries and definitive diagnosis of the disease relies upon bacterial culture, which requires suitable laboratory facilities and reliable antibody testing. More...
13 Apr 2017
Image: A photomicrograph of lung tissue stained with Grocott-Gomori methenamine silver nitrate. Pneumocystis jirovecii organisms are highlighted as black, disc-like entities within the alveolar cast (Photo courtesy of SPL).

Lymphocyte Subtyping Proves Useful in Predicting Pneumonia

Pneumocystis jirovecii is an opportunistic fungus that can cause interstitial pneumonia in the immunocompromised host and is associated with a high mortality rate. Antimicrobial prophylaxis reduces the occurrence of P. jirovecii pneumonia (PCP) considerably in susceptible patients. More...
13 Apr 2017
Image: The newly developed NanoDisk-MS assay, could significantly improve TB diagnosis and management because it is the first test that can measure the severity of active TB infections (Photo courtesy of Jason Drees, Biodesign Institute at Arizona State University).

Circulating TB Antigens Allows Rapid Diagnosis of Active Disease

A rapid and quantitative blood-based assay with high sensitivity and specificity for active Mycobacterium tuberculosis (Mtb) infections has been developed that can be used to monitor responses to anti-mycobacterial therapy. More...
13 Apr 2017
Image: The AsperGenius is a multiplex real-time PCR assay which rapidly diagnoses Aspergillus infections and simultaneously identifies multi-azole resistance (Photo courtesy of PathoNostics).

Novel Assay Discriminates Several Aspergillus Species

Invasive aspergillosis (IA) is mainly caused by Aspergillus fumigatus and when diagnosis is made early and first line therapy with voriconazole is initiated promptly, a relatively low mortality is observed. More...
12 Apr 2017
Image: Trypanosoma cruzi trypomastigote in a thin blood smear stained with Giemsa from a patient with Chagas disease (Photo courtesy of the CDC).

Performance of Chagas Disease Genotyping Assay Evaluated

Chagas disease remains a significant public health issue infecting six to seven million people worldwide. The factors influencing the clinical heterogeneity of Chagas disease have not been elucidated, although it has been suggested that different clinical outcome may be associated with the genetic diversity of Trypanosoma cruzi isolates. More...
07 Apr 2017
Image: The diagnosis, understanding, & treatment of Crohn’s disease may have now received a helping hand from a study aimed at developing a better blood test for the disease (Photo courtesy of the Biodesign Institute, Arizona State University).

Immunoproteomics Identifies New Biomarkers for Crohn’s Disease

Using a new screening approach, a study aimed at developing a better blood test for Crohn’s disease (CD) successfully identified several antibodies that could serve as diagnostic markers. More...
23 Mar 2017
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.

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