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Pathology

Image: The cumulative incidence of dementia according to lipid concentrations (triglycerides, HDL-C, LDL-C, total cholesterol) (Photo courtesy of the University of Bordeaux).

Plasma Lipids Associated Differently with Dementia Incidents

Dementia refers to a group of neurological disorders characterized by memory loss, cognitive impairment, and disability in activities of daily living. As the primary risk factor for dementia is old age, the prevalence of dementia is increasing dramatically with aging populations worldwide. More...
12 Apr 2017
Image: A representation of the molecular structure of KDR (kinase insert domain receptor) protein (Photo courtesy of Wikimedia Commons).

Targeted Microbubbles Enhance Ultrasound Detection of Malignant Tumors

By combining standard ultrasound technology with a novel type of targeted microbubbles, cancer researchers have developed a sensitive method for detecting malignant tumors that could reduce the number of biopsies needed to differentiate them from benign growths. More...
11 Apr 2017
Image: A molecular model of human papillomavirus (HPV) (Photo courtesy of Wikimedia Commons).

Mutations Linked to Improved Survival of Patients with HPV+ Carcinoma

Cancer researchers analyzed head and neck squamous cell carcinoma (HNSCC) data from The Cancer Genome Atlas to identify molecular characteristics of human papillomavirus (HPV)+ HNSCC and correlated them with patient outcomes. More...
11 Apr 2017
Image: Microfluidic rare-cell workflow for multiplexed western blotting of single patient-derived CTCs (Photo courtesy of University of California – Berkeley).

CTC Protein Expression Uses Microfluidic Western Blotting

Circulating tumor cells (CTCs) are rare tumor cells found in the circulatory system of certain cancer patients and the clinical and functional significance of CTCs is still under investigation. More...
06 Apr 2017
Image: The LSM510 META confocal microscope (Photo courtesy of Zeiss).

Technology Developed for Prostate Cancer Diagnosis and Monitoring

Early diagnosis of prostate cancer and evaluation of appropriate treatment options requires development of effective and high-throughput selective capture technology for exosomes that are positive for the expression of enzyme-biomarker, prostate-specific membrane antigen (PSMA). More...
06 Apr 2017
Image: The Easy-nLC 1000 liquid chromatography system (Photo courtesy of Thermo Fisher Scientific).

Phosphoproteins Identified as Biomarkers for Cancer

The state of protein phosphorylation can be a key determinant of cellular physiology such as early stage cancer, but the development of phosphoproteins in biofluids for disease diagnosis remains elusive. More...
05 Apr 2017
Image: The Combur 10 urinalysis test strips (Photo courtesy of Roche).

Early Serum Creatinine Predicts Post-Surgery AKI

Acute Kidney Injury (AKI) is a common and serious complication of cardiac surgery. Mild AKI occurs in nearly one in five patients undergoing cardiac surgery and is associated with a 19-fold increase in short-term mortality. More...
05 Apr 2017
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.

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