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Pathology

Image: A photomicrograph of a leukemic cell and an extracellular vesicle (Photo courtesy of University of Manchester).

Novel Leukemic Blood Test Has Massive Diagnostic Potential

The potential of a new test, which could revolutionize the way doctors diagnose and monitor common childhood leukemia, has been explored. The test is based on the fact that cancerous acute lymphoblastic leukemia cells produce and release special structures that can be traced in the blood. More...
07 Sep 2016
Image: A malignant melanoma on a patient’s skin (Photo courtesy of the National Cancer Institute).

Immune Analysis of Biopsies Predicts Response to Melanoma Immunotherapy

Immune response measured in tumor biopsies during the course of early treatment predicts which melanoma patients will benefit from specific immune checkpoint blockade drugs. More...
01 Sep 2016
Image: A histopathology showing simple columnar metaplasia of the epithelium of Barrett\'s Esophagus characterized by goblet cell (Photo courtesy of Nephron).

Genetic Analysis of Lesions Provides Accurate Esophageal Cancer Test

Barrett's Esophagus is a common condition that affects an estimated 1.5 million people in the UK alone, although many are undiagnosed. This condition involves normal cells in the esophagus being replaced by an unusual cell type called Barrett's Esophagus, and is thought to be a consequence of chronic reflux or heartburn. More...
31 Aug 2016
Image: The TMArrayer, a semi-automated tissue array device (Photo courtesy of Pathology Devices).

Prognostic Protein Biomarker Found for Esophageal Adenocarcinoma

Podocalyxin-like protein (PODXL) is a cell surface transmembrane glycoprotein, the expression of which has been associated with poor prognosis in a range of malignancies including glioblastoma multiforme, breast cancer, bladder cancer, periampullary and pancreatic adenocarcinoma and colorectal cancer. More...
31 Aug 2016
Image: A new study shows helical CT scans may reduce lung cancer mortality (Photo courtesy of MedicineWorld).

Study Highlights Importance of Regular Lung Cancer Screenings for Higher Risk Patients

Researchers have found that patients who tested negative for lung cancer (LC) in an LDCT (low-dose helical computed tomography) screening, but later went on to develop lung cancer within the following two years, had poorer outcomes than patients who initially had a non-cancerous positive screen test result. More...
29 Aug 2016
Image: A microscopic view of a colon cancer section (Photo courtesy of IDIBELL-Bellvitge Biomedical Research Institute).

Epigenetic Similarity in Cancer Cells Characterizes More Aggressive Tumors

Cancer researchers have found that the degree of epigenetic similarity among colorectal tumor cells was reflected in patients as significantly shortened relapse-free survival time and shortened time of overall survival. More...
29 Aug 2016
Image: The Rotor-Gene real-time PCR system (Photo courtesy of Qiagen).

Early Detection Identified for Leukemia Patients' Resistance to Therapy

A world-first breakthrough in the early detection of patients' resistance to a common treatment for chronic myeloid leukemia has been made. The discovery offers some hope that the patients' treatment could be changed sooner to improve their chances of survival. More...
25 Aug 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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