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Pathology

Image: A blood test for DNA methylation levels of the gene encoding zinc finger protein 154 (ZNF154) can diagnose common cancers (Photo courtesy of US National Institutes of Health).

Blood Test Developed to Detect Five Early-Stage Cancers

A blood test to diagnose common types of cancer is in development after it was found that five forms of the disease share a telltale chemical signature.  More...
28 Feb 2016
Image: Histopathology of metastatic carcinoma in liver tissue from a patient with colorectal cancer (Photo courtesy of Nikon).

Tumor Biopsies with Blood Monitoring Show Lesion-Specific Response

Metastatic tumors driven by drug-targetable genetic mutations become resistant to a targeted therapy drug and the usual practice is to biopsy a single metastatic lesion to test for new mutations that can guide the selection of next-line therapies.   More...
24 Feb 2016
Image: The SpectraMax Plus 384 Microplate Reader (Photo courtesy of Molecular Devices).

Immunomarker Found for Recurring HPV-Linked Oropharyngeal Cancers

Human papilloma virus infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk.  More...
24 Feb 2016

Failing Hearts Switch Fuels to Continue Generating Energy

A new study provides fresh biochemical insight into heart failure and may eventually lead to new diagnostic and pathology tests as well as therapeutic targets to prevent or slow progression of the disease.   More...
24 Feb 2016
Image: The Clarus 500 gas chromatography mass spectrometry (GC-MS) (Photo courtesy of PerkinElmer).

Fecal Analyses Leads to Inflammatory Bowel Disease Diagnosis

The development of sophisticated analytical techniques has enabled the study and interpretation of changes in the fecal volatile organic metabolites and its correlation with the pathophysiological mechanisms in the gut during health and disease.  More...
23 Feb 2016
Image: The Apogee Flow Cytometer used for detecting microparticles of prostate cancer (Photo courtesy of Schulich School of Medicine and Dentistry).

Prostate Cancer Detected in Blood Using Flow Cytometry

Current methods of detecting prostate cancer, such as the prostate-specific antigen test and biopsies, have limitations. PSA tests are based on measuring a specific protein released by the prostate gland, but do not provide a definitive diagnosis.  More...
22 Feb 2016
Image: The gas chromatography sensor system, Odoreader, is used for the diagnosis of urological malignancies (Photo courtesy of the University of Liverpool).

Urine Diagnostic Test Created for Urological Malignancies

A urine diagnostic test has been created for prostate cancer that could mean that invasive diagnostic procedures that men currently undergo eventually become a thing of the past.  More...
21 Feb 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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