We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
LGC Clinical Diagnostics

Download Mobile App




Absinthe's Effects were Due to High Alcohol Content

By Labmedica staff writers
Posted on 07 May 2008
Print article
Absinthe--the exotic green aperitif--was believed to possess mind-altering effects and toxic side effects when consumed to excess. A team of scientists from Europe and the United States has concluded that the culprit was the high alcohol content, rather than thujone, the compound widely believed responsible for absinthe's effects.

Although consumed diluted with water, absinthe contained about 70% alcohol, giving it a "140-proof wallop.” In late 19th-century, Paris bohemian artists and writers believed it expanded consciousness with psychedelic effects and called it "the Green Fairy” and "the Green Muse.” The drink's popularity spread through Europe and to the United States. However, illness and violent episodes among drinkers gave absinthe the reputation as a dangerous drug, and it was banned in Europe and elsewhere.

In a new study, Dirk W. Lachenmeier, Ph.D., from the Chemisches und Veterinäruntersuchungsamt (CVUA; Karlsruhe, Germany) and colleagues analyzed 13 samples of pre-ban absinthe from sealed bottles--"the first time that such a wide ranging analysis of absinthe from the pre-ban era has been attempted.” The study appeared online in the April 18, 2008 edition of the American Chemical Society's bi-weekly Journal of Agricultural and Food Chemistry.

The comprehensive chemical analysis included thujone, widely regarded as the "active” ingredient in absinthe. "It is certainly at the root of absinthe's reputation as being more drug than drink,” according to Dr. Lachenmeier. Thujone was blamed for "absinthe madness” and "absinthism,” a collection of symptoms including hallucinations, facial contractions, numbness, and dementia.

The researchers explained that scientists know very little about the composition of the original absinthe produced in France before that country banned the drink in 1915. Only a single study had previously analyzed one sample of preban absinthe.

However, the study by Dr. Lachenmeier found relatively small concentrations of thujone, amounts less than previously estimated and not sufficient to explain absinthism. Thujone levels in preban absinthe actually were about the same as those in modern absinthe, produced since 1988, when the European Union (EU) lifted its ban on absinthe production. Extensive laboratory tests found no other compound that could explain absinthe's effects.

"All things considered, nothing besides ethanol was found in the absinthes that was able to explain the syndrome of absinthism,” according to Dr. Lachenmeier. He added that scientific data could not explain preban absinthe's reputation as a psychedelic substance. Recent historic research on absinthism concluded that the condition probably was alcoholism.


Related Links:
Chemisches und Veterinäruntersuchungsamt
New
Gold Member
ANA & ENA Screening Assays
ANA and ENA Assays
Antipsychotic TDM AssaysSaladax Antipsychotic Assays
New
Herpes Virus Test
Human Herpes Virus (HHV-6) Real Time PCR Kit
New
Thyroxine ELISA
T4 ELISA

Print article

Channels

Hematology

view channel
Image: The smartphone technology measures blood hemoglobin levels from a digital photo of the inner eyelid (Photo courtesy of Purdue University)

First-Of-Its-Kind Smartphone Technology Noninvasively Measures Blood Hemoglobin Levels at POC

Blood hemoglobin tests are among the most frequently conducted blood tests, as hemoglobin levels can provide vital insights into various health conditions. However, traditional tests are often underutilized... Read more

Immunology

view channel
Image: Under a microscope, DNA repair is visible as bright green spots (“foci”) in the blue-stained cell DNA. Orange highlights actively growing cancer cells (Photo courtesy of WEHI)

Simple Blood Test Could Detect Drug Resistance in Ovarian Cancer Patients

Every year, hundreds of thousands of women across the world are diagnosed with ovarian and breast cancer. PARP inhibitors (PARPi) therapy has been a major advancement in treating these cancers, particularly... Read more

Microbiology

view channel
Image: HNL Dimer can be a novel and potentially useful clinical tool in antibiotic stewardship in sepsis (Photo courtesy of Shutterstock)

Unique Blood Biomarker Shown to Effectively Monitor Sepsis Treatment

Sepsis remains a growing problem across the world, linked to high rates of mortality and morbidity. Timely and accurate diagnosis, along with effective supportive therapy, is essential in reducing sepsis-related... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.