We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Download Mobile App




Hemoglobin Assay Performed with Photothermal Optical Sensor

By LabMedica International staff writers
Posted on 11 Jan 2015
An optical sensor, termed a photothermal spectral-domain optical coherence reflectometer (PT SD-OCR) is capable of direct measurement of hemoglobin concentration (Hb) without chemicals and preprocessing of blood.

The PT SD-OCR OCR measures Hb by quantifying refractive index changes of blood samples due to photothermal effect under the irradiation of 532-nm light and its diagnostic accuracy and precision has been evaluated in anemic patients.

Scientists at the Yonsei University (Seoul, Republic of Korea) and their colleagues used PT SD-OCR to measure Hb in 50 anemic patients, and examined its accuracy against a hematology analyzer. More...
Its precision was assessed by examining the standard deviation (SD) and coefficients of variation (CV) based on 20 repeated measurements on three blood sample and its performance was also compared with a hemoglobinometer.

The relative accuracy of the PT SD-OCR sensor was examined and the comparisons of the PT SD-OCR and HemoCue 201+ System (Angelholm, Sweden) against the results from the ADVIA 2120i hematology analyze (Siemens AG, Erlangen, Germany). An excellent correlation was observed between the results from the hematology analyzer and those of the PT SD-OCR sensor. The precision of the PT SD-OCR sensor was also comparable with the ADVIA 2120i analyzer and the HemoCue 201+ detector.

The authors concluded that simple and chemical-free operation of PT SD-OCR enabled rapid and accurate measurement of Hb in anemic patients. The sensor is expected to facilitate clinical procedures related to blood-related disorders in patient care. The PT SD-OCR sensor may therefore be readily utilized in clinical settings for hemoglobin detection and determination of proper treatment strategies for anemic patients. The study was published in the January 2015 issue of the journal Clinica Chimica Acta.

Related Links:

Yonsei University
HemoCue
Siemens AG 



Gold Member
Quality Control Material
iPLEX Pro Exome QC Panel
POC Helicobacter Pylori Test Kit
Hepy Urease Test
8-Channel Pipette
SAPPHIRE 20–300 µL
Automated MALDI-TOF MS System
EXS 3000
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Molecular Diagnostics

view channel
Image: DROP-AD in-house collection and extraction protocol and testing procedures (Huber, H., Montoliu-Gaya, L., Brum, W.S. et al.; Nat Med (20256); doi.org/10.1038/s41591-025-04080-0)

At-Home Blood Tests Accurately Detect Key Alzheimer's Biomarkers

Diagnosing Alzheimer’s disease typically relies on brain scans or spinal fluid tests, which are invasive, costly, and difficult to access outside specialist clinics. These barriers have limited large-scale... Read more
Copyright © 2000-2026 Globetech Media. All rights reserved.