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Clinical Chemistry

Image: The GPhone is a portable glucose sensing system integrated onto a smartphone (Photo courtesy of David Baillot/UC San Diego Jacobs School of Engineering).

Smartphone Case Offers Glucose Monitoring Regardless of Location

Currently, checking blood sugar levels can be a hassle for people with diabetes, especially when they have to pack their glucose monitoring kits around with them every time they leave the house. More...
20 Dec 2017
Image: The Neurofilament light (NF-L) ELISA allows fast quantification in less than three hours of NF-L in cerebrospinal fluid (Photo courtesy of UmanDiagnostics).

Blood Test Monitors Nerve Protein in MS Patients

Multiple sclerosis is a chronic inflammatory disease of the central nervous system (CNS) in which neuronal damage is present at an early stage. Due to both unpredictable and heterogeneous disease course and treatment response, biomarkers reflecting these processes are highly sought after. More...
12 Dec 2017
Image: The ThermoQuest Trace GC 2000 gas chromatography mass spectroscopy (GCMS) platform (Photo courtesy of Strona Polimerka).

Metabolites Altered in Chronic Kidney Disease

Chronic kidney disease (CKD) is an important public health problem with a high prevalence worldwide, from 10% to14% of the general population, and strongly increased age-standardized death rate, yet, there is a paucity of effective treatment options. More...
07 Dec 2017
Image: A piezoelectrically actuated pipette system is used as an inexpensive means to detect biological molecules associated with specific diseases, infection or other medical conditions (Photo courtesy of Purdue University).

Blood Biomarker Detected for Different Diseases

A method has been developed to identify biological markers in small amounts of blood that could be used to detect a myriad of diseases, infections and different medical conditions at early stages. More...
05 Dec 2017
Image: A histological section showing a obstructed extrahepatic bile duct. It exhibits residual expression of the enzyme called MMP-7 (shown in brown) (Photo courtesy of Cincinnati Children\'s Hospital Medical Center).

Diagnostic Test Identified for Pediatric Biliary Atresia

Biliary atresia is a rare disease of the liver and bile ducts that occurs in infants. Liver cells produce bile, which helps digest fat and carries waste products from the liver to the intestines. When an infant has biliary atresia, this flow is blocked and bile becomes trapped inside the liver, quickly causing liver damage and eventually liver failure. More...
05 Dec 2017
Image: The Access Hybritech new p2PSA test, part of the Prostate Health Index (phi) (Photo courtesy of Beckman Coulter).

Physicians Perform Fewer Prostate Biopsies Post-Phi Testing

Prostate cancer is the third-leading cause of cancer death in men, with one in seven receiving a diagnosis during his lifetime. In 2017, approximately 161,360 new cases of prostate cancer were identified, with 60% of those occurring in men 65 years of age or older. More...
04 Dec 2017
Image: The ARCHITECT i2000SR immunoassay analyzer (Photo courtesy of Abbott).

Newly Developed Automated Immunoassay Analyzed

Dipeptidyl peptidase-4 (DPP-4) may be a suitable biomarker to identify people with severe asthma who have greater activation of the interleukin-13 (IL-13) pathway and may therefore benefit from IL-13-targeted treatments. More...
29 Nov 2017
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.

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