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Clinical Chemistry

Tests for Smell Loss May Detect Alzheimer’s and PD

In a new approach to testing for olfaction dysfunction, researchers have developed “white smells,” mixtures of several odor molecules, which help reduce test bias and patient subjectivity, thus also creating a more globally applicable testing format. They suggest that these tests could also aid in earlier detection of neurological disorders that have been associated with olfaction problems. More...
16 Oct 2017
Image: The FreeStyle Libre Flash Glucose Monitoring System (Photo courtesy of Abbott).

Monitoring System No Longer Requires Fingerstick Calibration

People with diabetes must regularly test and monitor their blood sugar to make sure it is at an appropriate level, which is often done multiple times per day by taking a fingerstick sample and testing it with a blood glucose meter. More...
10 Oct 2017
Image: The COBAS c501 clinical chemistry analyzer (Photo courtesy of Roche Diagnostics).

Serum Magnesium Levels Linked to Dementia Risk

People with both high and low levels of magnesium in their blood may have a greater risk of developing dementia. Scientists have set out to find out if serum magnesium levels are associated with the risk of all-cause dementia and Alzheimer disease. More...
05 Oct 2017
Image: The UF-5000 fully automated urine analyzer (Photo courtesy of Sysmex Europe).

New Urine Analyzer Evaluated for Performance

Urinalysis is one of the most commonly requested laboratory tests, the third after the biochemical profile and the blood cell count, and it is very useful to screen for diseases of the kidney and urinary tract. More...
02 Oct 2017
Image: The qualitative point-of-care test CareStart G6PD RDT is a visual screening test that identifies G6PD deficient patients using whole blood sample. Panel A, no color change for sample with deficient G6PD enzymatic activity; Panel B, distinct purple color for sample with normal G6PD enzymatic activity (Photo courtesy of Access Bio).

Field Evaluation of Quantitative G6PD Diagnostics Reviewed

Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is the most common enzymopathy with at least 400 million individuals affected worldwide. More than 185 clinically relevant variants of G6PDd have been reported with a spectrum of associated enzyme deficiencies. More...
27 Sep 2017
Image: Gas chromatography-tandem mass spectrometry GCMS TQ-8030 GC-MS/MS (Photo courtesy of Shimadzu).

Biomarkers Prove Role of Food for Diabetics

Diet is frequently associated with both the development and prevention of type 2 diabetes (T2D), but there is a lack of objective tools for assessing the relation between diet and T2D. More...
27 Sep 2017
Image: An illustration of the ZnT8 protein imbedded in a fatty membrane and attached to the P-Gold Assay (Photo courtesy of Dr. Dax Fu).

Pancreatic Proteins Increase Sensitivity of Type 1 Diabetes Tests

There are approximately 29.1 million people living with diabetes and about 18,000 children in the USA are diagnosed with type 1 diabetes, with diagnoses peaking around the age of 14. The disease is controllable with insulin injections, pumps and constant blood sugar testing. More...
27 Sep 2017
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.

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