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Clinical Chemistry

Image: The cobas e 411immunoassay analyzer (Photo courtesy of Roche Diagnostics).

Performance of Immunosuppressant Drug Assay Kits Analyzed

Cyclosporine (CsA) and tacrolimus (TAC) are immunosuppressant drugs that are often used to treat autoimmune diseases and as transplantation therapy and therefore, their concentrations need to be monitored carefully. More...
08 Aug 2017
Image: Sensing device:  Simple characterizing target gas concentrations of human exhaled breath will lead to diagnose of the disease as well as physical condition (Photo courtesy of The Korea Advanced Institute of Science and Technology).

Innovative Nanosensor Developed for Disease Diagnosis

In human breath, diverse components are found including water vapor, hydrogen, acetone, toluene, ammonia, hydrogen sulfide, and carbon monoxide, which are more excessively exhaled from patients. Some of these components are closely related to diseases such as asthma, lung cancer, type 1 diabetes mellitus, and halitosis. More...
03 Aug 2017
Image: Histopathology of an immunostained diffuse amyloid beta plaque in a brain sample from a patient with Alzheimer’s disease (Photo courtesy of Dr. Dimitri P. Agamanolis, MD).

Blood Test Identifies Key Alzheimer's Marker

Decades before people with Alzheimer's disease develop memory loss and confusion, their brains become dotted with plaques made of a sticky protein, called amyloid beta that is thought to contribute to the disease and its progression. More...
02 Aug 2017
Image: The Assure H. Pylori Rapid Test is an immunochromatographic test for diagnosing infection from H. pylori in patients with gastric disorders (Photo courtesy of MP Biomedicals).

Serum Pepsinogen Validated for Atrophic Gastritis Diagnosis

Atrophic gastritis (AG) and intestinal metaplasia (IM) are well-recognized as high-risk conditions for developing gastric cancer (GC), and both have been identified as the precancerous lesions, but the clinical symptoms of AG are not specific. More...
01 Aug 2017
Image: The AbsoluteIDQ p180 kit identifies and quantifies more than 180 metabolites from five different compound classes (Photo courtesy of Biocrates Life Sciences).

Pre-Diagnostic Metabolite Concentrations Related to Cancer Risk

Prostate cancer is the second most commonly diagnosed cancer in men worldwide, but circulating insulin-like growth factor I is the only established risk factor that is potentially modifiable. More...
25 Jul 2017
Image: The BRAHMS Kryptor fully automated immunoanalyzer (Photo courtesy of Thermo Fisher Scientific).

Immunoassay Systems Compared for Trisomy Screenings

The biochemical serum markers free β-human chorionic gonadotropin (hCGβ) and pregnancy associated plasma protein A (PAPP-A) are used in screening for trisomy 21 (T21), trisomy 18 (T18), and trisomy 13 (T13) during the first trimester. More...
25 Jul 2017

Novel Biomarker Identifies Early Clinical CV Disease

Coronary artery disease (CAD) is one of the leading causes of morbidity and mortality worldwide, and the economic, social, and costs associated with treating CAD are very high. The severity of coronary artery lesions has been proven to be associated with the risk of future cardiovascular events. More...
19 Jul 2017
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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