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Molecular Diagnostics

Image: Photomicrograph showing histopathological appearance of an esophageal adenocarcinoma (dark blue – upper-left of image) and normal squamous epithelium (upper-right of image) (Photo courtesy of Nephron)

Genetic Changes Identified in Patients Who Progress to Esophageal Cancer

Barrett’s esophagus (BE), a predominantly benign metaplasia that arises in the esophagus in response to chronic gastric reflux, also develops somatic mutations, but can further evolve extensive genomic alterations which confer significantly increased risk of progression to esophageal adenocarcinoma (ESAD). More...
03 May 2022
Image: Troponin measurement via blood test a better way to measure risk for heart surgery patients (Photo courtesy of Unsplash)

Troponin Blood Test Offers Quick Method for Monitoring Patients after Cardiac Surgery

Validating a method with which to predict heart surgery patients most at risk is a big win. A large international study has now identified a first ever marker that is fast and reliable for the monitoring of patients after cardiac surgery. More...
03 May 2022
Image: Lipidomics provides new biomarkers for cardiovascular disease and Type II diabetes (Photo courtesy of DIfE)

Lipid Profiling of Blood Samples Reveals Biomarkers for Cardiometabolic Disease Risk

A lipidomics-based analysis of plasma samples from a large cohort of participants identified several lipids associated with cardiometabolic disease risk that might serve as biomarkers for diagnosis of cardiovascular disease and Type II diabetes. More...
29 Apr 2022
Image: New biomarker has potential to screen for those at high risk of dementia (Photo courtesy of Pexels)

Blood Biomarker Test Can Predict Dementia Before Symptoms Develop

New research has identified a blood biomarker that could help identify people with the earliest signs of dementia, even before the onset of symptoms. More...
29 Apr 2022
Image: The Bio-Rad QX200 Droplet Digital PCR (ddPCR) System provides absolute quantification of target DNA or RNA molecules for EvaGreen or probe-based digital PCR applications (Photo courtesy of Bio-Rad)

Duplex ddPCR Assay Evaluated for Salmonella and Shigella

Bacteria of the genus Salmonella and Shigella are important pathogens of infectious diarrhea. Salmonellosis was the second most commonly reported gastrointestinal infection in humans in the European Union in 2018. Shigella spp was the second leading cause of mortality caused by diarrhea among all ages in 2016 globally, accounting for 212,438 deaths. More...
28 Apr 2022
Image: Micrograph of a liver sample with trichrome stain, showing cirrhosis as a nodular texture surrounded by fibrosis (collagen is stained blue) (Photo courtesy of Wikimedia Commons)

Glycosylated Serum Proteins Are Biomarkers for Severity of Liver Fibrosis

A recently developed assay was used to measure changes in the N-linked glycans on IgG subtypes in the blood, which can serve as surrogate markers of liver disease and may be able to replace the gold standard method, liver biopsy. More...
28 Apr 2022
Image: The XDive superfast qPCR platform (Photo courtesy of Star Array)

Automated Nucleic Acid Extraction/Superfast PCR Platform to Enable Analysis of POC PCR Tests in Minutes

An automated nucleic acid extraction/superfast PCR platform for the Point-of-Care testing (POCT) market could enable POC PCR tests to be analyzed in just minutes in doctor's offices, laboratories, and hospitals. More...
28 Apr 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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