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Molecular Diagnostics

Image: The Illumina Next-Seq 500 sequencer (Photo courtesy of Adam Armstead)

Pediatric Cancer Sequencing Expands Relapse Treatment Options

New data has demonstrated that sequencing the tumors of relapsing pediatric cancer patients can uncover alterations linked to existing and emerging targeted therapies, potentially offering improved outcomes over standard chemotherapy. More...
21 Mar 2022
Image: Confocal microscope study of p-syn deposits in a dermal arteriole of a patient with PD (Photo courtesy of Dr. Alex Incensi)

Alpha-Synuclein Skin Deposits Characterize Parkinson’s Disease Patients

The detection of skin deposits of the neurodegenerative disease biomarker protein alpha-synuclein (p-syn) may be useful for the differential diagnosis of parkinsonism. More...
18 Mar 2022
Image: Plasma biomarker screening could improve accuracy of Alzheimer’s disease diagnosis (Photo courtesy of Pexels)

Blood Plasma Biomarkers Could Improve Diagnostic Tests for Alzheimer's Disease

Alzheimer's disease is the most common form of dementia, with the African American population at the greatest risk for developing the disease. The findings of the first study to focus on RNA molecules in plasma as biomarkers for Alzheimer's disease in African Americans could lead to the development of improved diagnostic tests for the disease. More...
18 Mar 2022
Image: Illumina has launched a groundbreaking comprehensive genomic profiling test for cancer in Europe (Photo courtesy of Illumina Inc.)

Groundbreaking DNA Test Evaluates Biomarkers in 517 Cancer-Relevant Genes across 30 Types of Solid Tumors

Illumina Inc. (San Diego, CA, USA) has launched TruSight Oncology (TSO) Comprehensive (EU), a single test that assesses multiple tumor genes and biomarkers to reveal the specific molecular profile of a patient's cancer. More...
17 Mar 2022
Image: The Cellometer K2 utilizes brightfield imaging and dual-fluorescence imaging to quickly and accurately identify and count individual cells. Cell count, concentration, diameter, and % viability are automatically calculated and reported (Photo courtesy of Nexcelom Bioscience)

Single Cell Characterization Acral Melanoma Identifies Novel Targets for Immunotherapy

Acral melanoma is a rare subtype that represents roughly 3% of all melanoma cases. Unlike typical melanoma that occurs on sun-exposed skin, acral melanoma develops on the nonhair bearing skin of the soles, palm and nail beds. There is very little information known about the development of acral melanoma. More...
16 Mar 2022
Image: New test could potentially diagnose Lyme disease (Photo courtesy of Unsplash)

New Test Could Help Diagnose Lyme Disease Sooner and Determine Treatment Efficacy

Traditional tests for Lyme disease, caused by a bite from an infected tick, can stay positive for prolonged periods of time after treatment, making it difficult for clinicians to diagnose persistent Lyme disease cases. Now, researchers have identified just such a testing mechanism that detects a type of antibody that infected individuals produce against a substance the Lyme bacteria acquires from the host in order to grow. More...
16 Mar 2022
Image: NovaSeq 6000 offers deeper and broader coverage through advanced applications for a comprehensive view of the genome (Photo courtesy of Illumina)

Expression, Microbiome Features Provide Pre-Treatment Lung Function Clues for Pediatric Patients

Microbial community and host gene expression features in lung samples may provide pre-treatment clues to risky lung function features in children receiving bone marrow transplants from healthy donor individuals, new research suggests. More...
15 Mar 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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