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Molecular Diagnostics

Image: A recently developed device enables faster testing of antibiotic-resistant bacteria (Photo courtesy of Dr. Seokheun `Sean` Choi)

Fast Antibacterial Susceptibility Testing by Measuring Electron Transfer Metabolism

A recently developed device facilitates bacterial antibiotics susceptibility testing by measuring the effect of these drugs on bacterial electron transfer metabolism. More...
07 Dec 2020
Image: The Tapestri Platform is the first and only single-cell multi-omics platform that is capable of simultaneously providing both genotype and phenotype data from the same cell, across thousands of cells (Photo courtesy of Mission Bio).

Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies

Myeloid malignancies are clonal diseases of hematopoietic stem or progenitor cells. Myeloid malignancies, including acute myeloid leukemia (AML), arise from the expansion of these hematopoietic stem and progenitor cells that acquire somatic mutations. More...
01 Dec 2020
Image: Lung cells infected with coronavirus (Photo courtesy of The Hebrew University of Jerusalem).

SARS-CoV-2 RNA Test Assessed Among Recovered COVID-19 Patients

Some patients who have recovered from coronavirus disease 2019 (COVID-19) with documented negative real-time polymerase chain reaction (RT-PCR) results at the time of recovery have had subsequent positive RT-PCR test results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). More...
25 Nov 2020
Image: Micrograph showing fibrosis of the liver caused by cirrhosis. The tissue in this example is stained with a trichrome stain, in which fibrosis is colored blue. The red areas are the nodular liver tissue (Photo courtesy of Wikimedia Commons)

Panel of Urinary Peptides Used to Diagnose Liver Fibrosis

A panel of 50 urinary peptides was shown to be a useful tool for the early diagnosis of liver fibrosis. More...
24 Nov 2020
Image: The portable MinION sequencing platform runs one flow cell and desktop GridION can run up to five flow cells at any time (Photo courtesy of Oxford Nanopore).

Metagenomic Sequencing Quickly Identifies Pathogens in Body Fluids

Metagenomic next-generation sequencing (mNGS) is a shotgun sequencing approach in which all of the nucleic acid (DNA and RNA) in a clinical sample is sequenced at a very high depth, 10-20 million sequences per sample. More...
23 Nov 2020
Image: A clot in the neck or brain can lead to a stroke (Photo courtesy of Mayo Clinic)

Blood Biomarker Protein Correlates with Severity of Brain Damage in Stroke Patients

Researchers have identified a stroke-related biomarker protein that correlates with the severity of brain tissue damage as well as with functional outcome and mortality. More...
23 Nov 2020
Image: Histological features of COVID-19 lungs (Photo courtesy of the University of Trieste).

COVID-19 Lung Damage Caused by Persistence of Abnormal Cells

Several uncertainties still relate to the involvement of other organs in COVID-19. Besides indirect multi-organ injury, a few reports have suggested the possibility of direct injury caused by viral replication in brain, heart and kidney. More...
19 Nov 2020
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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