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Molecular Diagnostics

Image: The Bio-Rad CFX96 Real-Time PCR Platform (Photo courtesy of Nanyang Technological University).

Streamlined Assay Improves Prenatal Detection of Alpha-Thalassemia

Alpha-Thalassemia is a group of recessively inherited hemoglobin (Hb) disorders that result from decreased or absent synthesis of α-globin chains, affecting up to 5% of the world's population, mainly prevalent in the Mediterranean coastal countries, Southeast Asia, some African countries, and southern China. More...
09 Jun 2020
Image: Photomicrograph of pediatric pilocytic astrocytoma, a brain tumor, showing the characteristic bipolar cells with long hair-like processes (Photo courtesy of Nephron)

Precision Oncology Confers Clinical Benefit in Relapsed Pediatric Cancer

The Individualized Therapy for Relapsed Malignancies in Childhood (INFORM) registry has been created to help develop precision medicine-based approaches and to analyze their effectiveness across high-risk relapsed or refractory pediatric cancers. More...
08 Jun 2020
Image: Transmission electron microscope image showing SARS-CoV-2, the virus that causes COVID-19 (Photo courtesy of [U.S.] National Institute of Allergy and Infectious Diseases)

Blood Protein Biomarkers Predict Outcome of a Patient’s COVID-19 Infection

A panel of blood biomarkers in patients with COVID-19 has demonstrated the potential to predict the severity of their symptoms and likely outcome of the infection. More...
08 Jun 2020
Image: The Cepheid Xpert Xpress SARS-CoV-2 test was compared favorably with other molecular diagnostic tests (Photo courtesy of Cepheid).

Study Evaluates Molecular Diagnostics Tests for SARS-CoV-2

The explosion of COVID-19 cases in the USA has highlighted the critical role diagnostic testing plays in medical and public health decision making in containing and mitigating the SARS-CoV-2 pandemic. More...
04 Jun 2020
Image: Left panel: Histological sections of the left tonsillar tissue found a 2 mm non-keratinizing squamous cell carcinoma, with focal stromal invasion  comparing non-affected area in the left tonsil (Photo courtesy of Queensland University of Technology).

Saliva-Based Assay Developed for HPV-Driven Oropharyngeal Cancer

The incidence of high-risk human papillomavirus (HR-HPV−16, −18, −33) driven oropharyngeal cancer (OPC) is rapidly increasing in developed countries. HPV-driven OPCs have surpassed cervical cancer as the most common HPV-driven cancer in the USA. More...
04 Jun 2020
Image: Cartoon representation of the molecular structure of blaTEM (beta-lactamase) protein (Photo courtesy of Wikimedia Commons)

Changes in Bacterial Load and Serum Cytokine Levels Predict Likelihood of Dying from Sepsis

A testing method for the sensitive and rapid quantification of serum cytokines and bacterial load can be used to predict the likelihood of a patient dying from sepsis or septic shock. More...
03 Jun 2020
Image: Pre-eclampsia: high magnification micrograph of hypertrophic decidual vasculopathy, as seen in pregnancy-induced hypertension. (Photo courtesy of Wikimedia Commons)

Serum MicroRNAs Predict Likelihood of Pregnant Women Developing Pre-Eclampsia

MicroRNA biomarkers have been identified in the blood of asymptomatic pregnant women that can be used to predict the potential onset of pre-eclampsia. More...
02 Jun 2020
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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