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Molecular Diagnostics

Image: The association of genetic liability to psychotic experiences with neuropsychotic disorders and traits has been explored (Photo courtesy of Cardiff University).

Genetic Links Uncovered Between Psychotic Experiences

Psychotic experiences, such as hallucinations and delusions, are features of psychiatric disorders, such as schizophrenia, but they are also reported by approximately 5% to 10% of the general population. More...
09 Oct 2019
Image: A peripheral blood smear showing Wuchereria bancrofti microfilaria, found in a patient with lymphatic filariasis (Photo courtesy of Medical Chemical Corporation).

Molecular Changes Associated with Treating Lymphatic Filariasis

Lymphatic filariasis (LF) is a disabling neglected tropical disease that is caused by the mosquito-borne filarial parasites Wuchereria bancrofti, Brugia malayi and B. timori. Adult worms live in the human host’s lymphatic system and release larval parasites (microfilariae or Mf) that circulate in the blood. More...
09 Oct 2019
Image: A custom-designed Affymetrix Axiom array (Photo courtesy of Thermo Fisher Scientific).

Some High-Cholesterol Genes Differ Between Countries

Genome-wide association studies (GWAS) have been very successful in identifying genetic variants linked to cardiovascular disease (CVD) and to cardiometabolic traits. Due to the improving predictive accuracy of these variants, genetic risk prediction could soon be implemented in clinical settings. More...
09 Oct 2019
Image: The RainDrop droplet digital polymerase chain reaction system (ddPCR) (Photo courtesy of RainDance Technologies).

Non‐Invasive Prenatal Diagnosis of Spinal Muscular Atrophy Validated

The discovery of cell‐free DNA (cfDNA) in maternal plasma has enhanced the development of non‐invasive prenatal testing (NIPT). More...
08 Oct 2019
Image: A typical mitochondrial network (green) in two human cells (Photo courtesy of Wikimedia Commons).

Mitochondrial Clearance Failure Provides Diagnostic Marker for Parkinson's Disease

Failure of mitochondria to remove the Miro1 protein following depolarization provides a biomarker that can be used for diagnosis of Parkinson's disease. More...
07 Oct 2019
Image: Scanning electron micrograph of a pair of Schistosoma mansoni (Photo courtesy of the Davies Laboratory Uniformed Services University).

RT-PCR Evaluated for Diagnosis of Imported Schistosomiasis

Schistosomiasis is one of the most important human parasitic neglected tropical diseases. It is a major source of morbidity and mortality in Africa but also in South America, the Caribbean, the Middle East, and Asia. More...
03 Oct 2019
Image: The ImageQuant LAS 4000 biomolecular imager (Photo courtesy of GE Healthcare).

Breakthrough Kit May Enable Early Alzheimer's Diagnosis

Alzheimer’s disease (AD) is a neurodegenerative disease with the highest incidence and is one of the most common central neurological disorders. According to the World Health Organization (WHO), in 2016, the global number of individuals who lived with dementia was 43.8 million. More...
02 Oct 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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