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Immunology

Image: An immunohistochemistry of fine needle aspirates in acinic cell carcinoma (AciCC) for SRY-related HMG-box 10 (SOX10) and 2-deoxyglucose-6-phosphate phosphatase (DOG1) (Photo courtesy of Emory University School of Medicine).

Ancillary Tests Developed for Salivary Gland Pathology

Salivary gland tumors represent a diverse set of tumors with a broad range of biologic behaviors, ranging from completely benign tumors to low-grade malignancies to high-grade malignancies. More...
03 May 2017
Image: A scanning electron micrograph (SEM) showing how the single-molecule array digital ELISA is carried out in tiny, femtoliter-volume wells containing beads capable of binding single molecules (Photo courtesy of Rodero MP et al).

Ultrasensitive ELISA Enables Detection of Interferon

Researchers have developed a method for ultrasensitive detection of interferon alpha protein linked to multiple autoimmune diseases, including systemic lupus erythematosus (SLE) and dermatomyositis. The technique will aid the diagnosis and treatment, and has also begun to reveal differential levels and cellular sources among different autoimmune diseases. More...
02 May 2017
Image: Fluorescence micrograph of captured plasma cells from a clinical sample. Red fluorescence denotes CD138, while green denotes κ light chain antibody (Photo courtesy of Massachusetts Institute of Technology).

Novel Technique Captures Plasma Cells from Myeloma Patients

Multiple myeloma is a cancer of the plasma cells, which are white blood cells produced in bone marrow that churn out antibodies to help fight infection. When plasma cells become cancerous, they produce abnormal proteins, and the cells can build up in bone marrow, ultimately seeping into the bloodstream. More...
27 Apr 2017
Image: Indirect fluorescent antibody test for Toxoplasma gondii, diffuse staining is considered positive (Photo courtesy of SPL).

New Immunoassay Evaluated for Toxoplasmosis

The infection by Toxoplasma gondii, an obligate intracellular parasite, is generally benign but can be particularly severe during pregnancy, leading to malformations of the fetus or a series of complications in the newborn. More...
25 Apr 2017
Image: The FLEXMAP 3D flow-based suspension array system for advanced and versatile multiplexing platform (Photo courtesy of Luminex).

Low Levels of Immune Molecules Found in ME/CFS

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling disorder with complex features that can include fatigue, memory and concentration deficits. More...
21 Apr 2017
Image: The Chagas Stat-Pak rapid test for the diagnosis of Chagas disease (Photo courtesy of Chembio).

Rapid Tests Conclusively Diagnose Chagas Disease

Chagas disease is caused by infection with the Trypanosoma cruzi that are generally transmitted by triatomine vectors that are endemic to the Americas. It affects several million people and severe cardiac and/or digestive complications occur in about 30% of the chronically infected patients. More...
19 Apr 2017
Image: A ribbon model of von Willebrand factor, mutations of which can cause the inherited blood disorder von Willebrand Disease (Photo courtesy of Wikimedia).

Innovative Von Willebrand Factor Test Launched in US

A center for blood diseases has launched a new test in the United States to more accurately measure activity of von Willebrand Factor (VWF), one of the blood-clotting proteins, for people with the inherited bleeding disorder von Willebrand disease (VWD). More...
18 Apr 2017
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.

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