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Immunology

Image: Osteopontin is a biomarker for multisystem inflammatory syndrome in children (MIS-C) (Photo courtesy of Getty Images)

Osteopontin Biomarker Evaluated for COVID-19 Severity and MIS-C

Multisystem inflammatory syndrome in children (MIS-C) is a serious condition that appears to be linked to coronavirus disease 2019 (COVID-19). Most children who become infected with the COVID-19 virus have only a mild illness. More...
27 Oct 2021
Image: The Optilite Clinical Chemistry Protein Analyzer (Photo courtesy of The Binding Site)

Sensitive Method Detects Free Monoclonal Light Chains in Serum

Neoplastic monoclonal gammopathies (NMG) consist of monoclonal gammopathy of undetermined significance (MGUS), asymptomatic or smoldering multiple myeloma (SMM) and multiple/plasma cell myeloma (MM). More...
26 Oct 2021
Image: The fully automated Pylon 3-D immunochemistry system (Photo courtesy of ET HealthCare)

Biosensor Platform Monitors SARS-CoV-2 Antibody Durability

Low initial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody titers dropping to undetectable levels within months after infections have raised concerns about long-term immunity. More...
20 Oct 2021
Image: Low anti-SARS-CoV-2 S antibody levels predict increased mortality and dissemination of viral components in the blood of critical COVID-19 patients (Photo courtesy of Instituto de Salud Carlos III)

Low Anti-SARS-CoV-2 S Antibody Levels Predict Increased Mortality

Anti-SARS-CoV-2 spike (S) antibodies bind to multiple domains in this viral protein. Host antibodies directed at the receptor binding domain (RBD) mediate inhibition of viral attachment to cell surface receptors. More...
20 Oct 2021
Image: Psoriatic plaques, showing a silvery center surrounded by a reddened border (Photo courtesy of Jane Bianchi, BA)

Hematological Parameters Compared in Psoriasis Patients

Psoriasis is a chronic, immune-mediated disorder that can involve the skin and/or joints. Four clinical types of psoriasis are currently recognized: psoriasis vulgaris (PsV), pustular psoriasis (PP), erythrodermic psoriasis (PsE), and arthritic psoriasis (PsA). More...
19 Oct 2021
Image: Fully assembled liquid flow assay developed in the Sarioglu lab (Photo courtesy of Allison Carter)

New Flow Control Technology Turns Simple COVID-19 Dipstick Tests into Complex Biomedical Assays

A team of researchers attempting to overcome the limitations of dipsticks have developed a flow control technology that can turn these simple tests into complex biomedical assays. More...
19 Oct 2021
Image: Schematic diagram showing Anti-Neutrophil cytoplasmic antibody ANCA-induced ‘activation’ of neutrophils causing inflammation of the blood vessel wall (Photo courtesy of Addenbrooke’s Hospital)

Serum Progranulin Predicts High Activity of ANCA-Associated Vasculitis

Anti-Neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of chronic multisystem autoimmune diseases with substantial mortality and morbidity and frequent relapses. Progranulin is known to assume both pro-inflammatory roles and anti-inflammatory roles in the immune response. More...
18 Oct 2021
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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