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Immunology

Image: The cobas c 701 module is a high throughput clinical chemistry module that performs photometric assay tests for a wide range of analytes (Photo courtesy of Roche Diagnostics)

Serum α-L-Fucosidase Activity Measured for COVID-19 Infection

An unusual fucosylated LacdiNAc in the receptor-binding domains of the spike protein of COVID-19 has been observed. Reduced fucosylation was also found in a specific Fc domain of IgG antibodies in COVID-19 patients that enhanced the interactions with the activating FcγR, FcγRIIIa. More...
22 Apr 2021
Image: The Rayto RT‐6500 microplate reader (Photo courtesy of Rayto Life and Analytical Sciences)

Urinary Heat Shock Protein 70 Evaluated in Chronic Prostatitis

Chronic prostatitis (CP) is a common, but a confusing urological disease that seriously affects men's lives and health and cannot be ignored. The incidence rate is increasing, and the disease is affecting younger men and long‐term prostatitis affects male sexual function. More...
21 Apr 2021
Image: The BreathID Exalenz device (Photo courtesy of Meridian Bioscience)

Breath Test Determines Severity of Methylmalonic Acidemia Disease

Methylmalonic acidemia is a disorder in which the body cannot break down certain proteins and fats. The result is a buildup of a substance called methylmalonic acid in the blood. This condition is passed down through families and is one of several conditions called an "inborn error of metabolism." More...
20 Apr 2021
Image: Snibe Diagnostic’s Maglumi HIV Ab/Ag Combi CLIA Assay (4th-Generation) Secures CE Mark (List A) (Photo courtesy of Snibe Diagnostic)

Snibe Diagnostic’s Maglumi HIV Ab/Ag Combi CLIA Assay (4th-Generation) Secures CE Mark (List A)

Snibe Diagnostic (Shenzhen, China) has received the CE certificate (List A) for the Maglumi HIV Ab/Ag Chemiluminescence Immunoassay (CLIA) assay. More...
16 Apr 2021
Image: Randox Discovery Diagnostic Analyzer Wins 2021 Red Dot Award for High Design Quality (Photo courtesy of Randox Laboratories)

Randox Discovery Diagnostic Analyzer Wins 2021 Red Dot Award for High Design Quality

Randox Laboratories’ (Crumlin, UK) Discovery, a diagnostic analyzer which can consolidate molecular and immunoassay testing on one compact benchtop platform, has received the 2021 Red Dot Award for High Design Quality. More...
16 Apr 2021
Image: Immune T cells lymphocytes can seek and destroy a cell (green) infected with and making copies of SARS-CoV-2 (yellow) (Photo courtesy of US National Institute of Allergy and Infectious Diseases)

T Cells Recognize Recent SARS-CoV-2 Variants

Due to the proofreading ability of the coronavirus (CoV) RNA-dependent RNA polymerase, the evolution of the global SARS-CoV-2 viral population during the current pandemic has been relatively constrained as compared to other endemic RNA viruses that do not possess this ability. More...
15 Apr 2021
Image: Inflammation of the pancreatic islets with mononuclear cells including T-cells is the hallmark of Type 1 diabetes (Photo courtesy A. van Halteren)

Type 1 Diabetes Onset Preceded by Gene Expression Changes

Type 1 diabetes (T1D) results from insufficient insulin production and is thought to result from an immune reaction against the body’s own pancreatic β cells. The exact cause of T1D remains unknown, although asymptomatic islet autoimmunity lasting from weeks to years before diagnosis raises the possibility of intervention before the onset of clinical disease. More...
14 Apr 2021
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.

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