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Microbiology

Image: The Diagnostic Performance of C6 Enzyme Immunoassay for Lyme Arthritis has been evaluated (Photo courtesy of Lonnie R. Marcum, PT, BSHCA)

Immunoassay May Help Identify Pediatric Lyme Arthritis

 In the USA, Lyme arthritis is the most common feature of late stage infection with the tick-borne spirochete, Borrelia burgdorferi, usually beginning months after the initial tick bite. Patients with Lyme arthritis have intermittent or persistent attacks of joint swelling and pain in one or a few large joints, especially the knee, usually over a period of several years, without prominent systemic manifestations. More...
07 Jan 2020
Image: Flongle is an adapter (flow cell dongle) for the MinION or GridION that enables direct, real-time DNA or RNA sequencing on smaller, single-use flow cells (Photo courtesy of Oxford Nanopore Technologies).

Nanopore Sequencing Rapidly Diagnoses Gut Condition in Preterm Infants

 The culture-independent, sensitive, data-rich nature of metagenomic sequencing, combined with powerful bioinformatics tools, have allowed scientists to differentiate patient groups from healthy individuals based on their microbial profiles. More...
03 Jan 2020
Image: The NUCLISENS EASYMAG instrument is designed to meet the most critical needs when it comes to premium quality total nucleic acid extraction. The system automates an enhanced magnetic silica version of BOOM technology, a gold standard for efficient universal extraction of RNA and DNA (Photo courtesy of bioMérieux).

Asthma Severity Linked to Microbiome of Upper Airway

More than six million children under the age 18 have asthma in the USA. Asthma exacerbations have high impact on children, their families, the health care system, and may lead to subsequent decline in lung function. More...
01 Jan 2020
Image: Point-of-care serodiagnostic test for early-stage Lyme disease using a multiplexed paper-based immunoassay and machine learning (Photo courtesy of American Chemical Society).

Paper-Based Test Could Diagnose Lyme Disease at Early Stages

 Caused by the tick-borne spirochete Borrelia burgdorferi, Lyme disease (LD) is the most common vector-borne infectious disease in North America and Europe and timely diagnosis and treatment are effective in preventing disease progression. More...
01 Jan 2020
Image: The C. DIFF QUIK CHEK COMPLETE test is a rapid membrane enzyme immunoassay for the simultaneous detection of Clostridium difficile glutamate dehydrogenase antigen and toxins A and B in a single reaction well (Photo courtesy of Abbott)

C. Diff Carriers Are Source of Infections in Hospitals

 Clostridioides difficile is a spore-forming, gram-positive anaerobic bacillus spread by fecal–oral transmission of spores, which remain viable for long periods of time ex vivo. Although C. difficile carriers do not have diarrhea, they do shed spores that can contaminate environmental surfaces. More...
26 Dec 2019
Image: The LH 750 hematology analyzer is equipped with advanced technologies with nucleated red blood cell (NRBC) enumeration and random access capabilities (Photo courtesy of Fameco Medical)

Hepatic Dysfunction and Coagulopathy Quantified in Fatal Dengue Fever

 Dengue fever (DF) is currently one of the most severe public health problems. Each year, an estimated 390 million dengue infections occur around the world. Clinical presentations of dengue are diverse and non-specific, often with unpredictable clinical progression and outcome. More...
24 Dec 2019
Image: The Fuji dri-chem immuno AG cartridge FluAB kit (Photo courtesy of Fujifilm Corporation)

High Performance of Rapid Influenza Diagnostic Test Validated

 Influenza is a leading infectious cause of morbidity and mortality worldwide. Annually, about 5% to 10% of adults and 20% to 30% of children have symptoms of influenza-like illness (ILI), and approximately 650,000 deaths secondary to influenza occur each epidemic season. More...
19 Dec 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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