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Microbiology

Image: A histopathology of Hepatitis C viral infection of the liver, necrosis and inflammation are prominent, and there is some steatosis (Photo courtesy of the University of Utah Medical School).

Novel Test Allows for One-Step Diagnosis of HCV Infection

The current standard in diagnosing Hepatitis C virus (HCV) infection requires two sequential steps that make it suboptimal, costly, inconvenient, time consuming, and globally not widely available or affordable. More...
21 Jun 2016
Image: In the new pathogen-detection technology, engineered FcMBL proteins coupled to magnetic beads (grey) specifically bind to carbohydrate molecules on the surface of pathogens, like infectious E. coli (blue) in this electron micrograph, or on fragments of dead pathogens circulating in the bloodstream. After isolation in a magnetic field, the total pathogenic material is quantified with a second FcMBL protein linked to a color-producing enzyme (Photo courtesy of Wyss Institute at Harvard University).

Novel Test May Enable Quick Reliable Detection of Sepsis

Researchers have developed a rapid specific diagnostic assay that could help physicians decide within an hour whether a patient has a systemic infection. Its potential to detect pathogen materials was demonstrated in animal studies and a prospective human clinical study, whose results also suggested that it could also serve as a companion diagnostic to monitor antibiotic and dialysis-like sepsis therapies. More...
20 Jun 2016
Image: The MassARRAY system for iPlex single nucleotide polymorphism (SNP) genotyping (Photo courtesy of Sequenom).

Genes Identified That Increase Children's Risk Of Blood Infection

Bacteremia is a bacterial infection of the bloodstream, and a major cause of illness and death in sub-Saharan Africa but little is known about whether human genetics play a part. More...
16 Jun 2016
Image: The mobile suitcase laboratories. The mobile set up was built to host all reagents and equipment to perform the SpeedXtract (left suitcase). Another suitcase was used to perform the RPA assay (right suitcase) (Photo courtesy of University of Gottingen).

Mobile Suitcase Laboratory Rapid Detects Visceral Leishmaniasis

Leishmania donovani (LD) is a protozoan parasite transmitted to humans from sand flies, which causes Visceral Leishmaniasis (VL) and currently, the diagnosis is based on presence of the anti-LD antibodies and clinical symptoms. More...
15 Jun 2016
Image: A diagram of Merkel cell polyomavirus preferentially infecting dermal fibroblasts in human skin (Photo courtesy of Jianxin You, PhD).

Merkel Cell Polyomavirus Infection Can Cause Lethal Carcinoma

A benign virus normally found in the skin can lead to a type of rare, lethal skin cancer; specifically, infection by the Merkel cell polyomavirus can lead to Merkel cell carcinoma in immune-compromised individuals. More...
14 Jun 2016
Image: The Idylla fully automated, real-time polymerase chain reaction (rt-PCR) based molecular diagnostics system (Photo courtesy of Biocartis).

Ebola Virus Triage Test Granted Emergency Use Authorization

The 2014 Ebola virus outbreak in West Africa was the largest outbreak since its discovery 40 years ago and with over 11,000 deaths reported and affecting multiple countries, that outbreak demonstrated a clear need for improved infectious disease surveillance and management. More...
14 Jun 2016
Image: The MiSeq desktop sequencer (Photo courtesy of Illumina).

Primary Sclerosing Cholangitis Characterized By Intestinal Dysbiosis

Primary Sclerosing Cholangitis also known as PSC, is a liver disease with no effective medical treatment and liver transplantation is the only proven long-term treatment of PSC, although only a fraction of individuals with PSC will ultimately require it. More...
08 Jun 2016
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.

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