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Pathology

Image: A colored scanning electron micrograph (SEM) of a Helicobacter pylori bacterium (red) in the stomach (Photo courtesy of Steve Gschmeissner / SPL).

Atrophic Gastritis Prevalence Determined by Serological Evidence

Gastric cancer, among the most common cancers, is a leading cause of cancer deaths worldwide. More...
19 Feb 2019
Image: The Benchmark XT System, a fully automated staining system (Photo courtesy of Ventana Medical Systems).

Genetic Causes of Salivary Gland Carcinoma Discovered

Acinic cell carcinoma is the third most common malignant form of salivary gland cancer. These tumors are similar to normal salivary gland tissue and occur most frequently in the parotid gland. Until now, the molecular causes for the illness were unknown. More...
13 Feb 2019
Image: The Mastercycler X50 for polymerase chain reactions (Photo courtesy of Eppendorf).

Microbiome Helps Identify Patients with Early-Stage Cancer

Nearly 10,000 people are diagnosed with pancreatic cancer in the UK each year, with less than 1% surviving beyond ten years. More...
12 Feb 2019
Image: Positron Emission Tomography (PET) scans of the brain of a normal patient (left) versus an Alzheimer\'s disease patient, which may have been detected earlier by measuring Neurofilament light chain (NfL) in CSF (Photo courtesy of Science Photo Library).

Blood Test Detects Brain Damage Years before Symptoms

Alzheimer's disease is a major cause of dementia that destroys brain cells and tissue. As the brain damage spreads, it leads to symptoms such as confusion, memory loss, and diminishing capacity to function. Eventually, the person can no longer lead an independent life. More...
07 Feb 2019
Image: Various types of data analysis using BeadStudio Methylation Module (Photo courtesy of Phoebe Lu).

DNA Methylation Test Detects Early Aggressive Prostate Cancer

Liquid biopsies that noninvasively detect molecular correlates of aggressive prostate cancer (PCa) could be used to triage patients, reducing the burdens of unnecessary invasive prostate biopsy and enabling early detection of high-risk disease. More...
06 Feb 2019
Image: Vials of cerebrospinal fluid that can be sequenced for cell-free DNA in glioma patients (Photo courtesy of James Heilman, MD).

CSF Liquid Biopsy Sequencing Tracks Glioma Evolution

Genetic tumor profiling of gliomas is used to classify disease and guide therapy, but involves brain surgery for tissue collection; repeated tumor biopsies may be necessary for accurate genotyping over the course of the disease. More...
06 Feb 2019
Image: Porphyromonas gingivalis gingipains in the neurons of Alzheimer\'s brain. P. gingivalis gingipains = red, neurons = yellow, astrocytes = green (Photo courtesy of Cortexyme).

Bacterial Pathogen Discovered in Brains of Alzheimer's Patients

Alzheimer’s disease (AD) patients exhibit neuroinflammation consistent with infection, including microglial activation, inflammasome activation, complement activation, and altered cytokine profiles. More...
06 Feb 2019
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.

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