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Pathology

Image: Histopathology of a testicular germ cell tumor consisting of teratoma, embryonal carcinoma yolk sac tumor and syncytiotrophoblasts (Photo courtesy of Lee Moffitt Cancer Center).

Four Susceptibility Loci Identified for Testicular Germ Cell Tumor

Testicular germ cell tumor is the most common cancer in men aged 15 to 45 years, with over 18,000 new cases diagnosed annually in Europe and the incidence of TGCT has approximately doubled over the last four decades in Western Europe, which implicates environmental or lifestyle factors as risk determinants.  More...
08 Nov 2015
Image: Immunohistochemistry of αB-crystallin protein expression in a human breast tumor (Photo courtesy of University of Wisconsin).

Test Predicts Whether Breast Cancer Metastasizes to the Brain

Women can live for years with breast cancer that has begun to spread around the body, but the exception is when the cancer spreads to the brain, which usually indicates a woman is in her last few months of life.   More...
08 Nov 2015
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FDA Approves First of its Kind Companion Dx for Lung Cancer Patients

The US Food and Drug Administration have approved the first complementary diagnostic test to support use of OPDIVO for non-squamous non-small-cell lung cancer therapy.  More...
02 Nov 2015
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Prognostic Index Identifies Risk of Testicular Cancer Relapse

The assessment of just three features can identify those at most at risk of relapse of a common kind of testicular cancer known as non-seminomatous germ cell tumor even where there is no evidence of tumor spread.   More...
02 Nov 2015
Image: Photomicrograph of alveolar rhabdomyosarcoma showing nodules of tumor cells separated by hyalinized fibrous septae (50x, HE stain). Inset: Discohesive large tumor cells with hyperchromatic nucleus and scant cytoplasm (200x, HE stain) (Photo courtesy of Wikimedia Commons).

Five-Gene Panel Confirmed as Diagnostic for High-Risk Pediatric Rhabdomyosarcoma

A recently published paper confirmed the usefulness of a five-gene panel for identifying children with a high risk form of the muscle cancer rhabdomyosarcoma.  More...
27 Oct 2015
Image: The EGFR Mutation Test v2 was designed to run on a cobas 4800 instrument such as that shown here (Photo courtesy of Roche).

Liquid Biopsy Paves the Way for Personalized Lung Cancer Treatment

The biotech company Roche, an acknowledged leader in research-focused healthcare with combined strengths in pharmaceutical and diagnostic innovation, is focusing on the development of new tools for personalized lung cancer diagnostics and treatment.  More...
27 Oct 2015
Image: PointMan DNA enrichment technology for highly sensitive detection of genetic mutations (Photo courtesy of EKF Diagnostics).

DNA Enrichment Increases Usefulness of Liquid Biopsy Technology

DNA enrichment technology was a critical tool used in a study that detected genetic variations in circulating tumor cells in blood samples from non-small-cell lung cancer patients.  More...
27 Oct 2015
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ANA & ENA Screening Assays
ANA and ENA Assays
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IH-500 NEXT
New
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Oncology Molecular Diagnostic Test
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New
17 Beta-Estradiol Assay
17 Beta-Estradiol Assay


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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