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BioResearch

Image: Micrograph of normal heart cells (cardiomyocytes). Nuclei are shown in blue (Photo courtesy of Yoshida Laboratory, Kyoto University).

Successful Cardiac Repair Depends on Maturity of Transplanted Stem Cells

A team of Japanese cells biologists has shown that the likelihood of stem cell therapy successfully repairing damaged heart muscle depends to large extent on the maturity of the stem cells at the time they are transplanted into the damaged organ.  More...
18 Jan 2016
Image: Micrograph of functioning human pancreatic cells following transplantation into a mouse (Photo courtesy of Dr. Saiyong Zhu, University of California, San Francisco).

Reprogrammed Skin Cells Produce Insulin and Prevent Diabetes in Mouse Model

Advances in chemical and genetic methods for cellular reprogramming have enabled researchers to convert human skin cells into fully functional pancreatic beta cells.  More...
17 Jan 2016
Image: Scanning electron micrograph of Clostridium difficile bacteria from a stool sample (Photo courtesy of the CDC - [US] Centers for Disease Control and Prevention).

Secondary Bile Acids in the Large Intestine Inhibit Clostridium difficile Growth

Secondary bile acids that result from bacterial metabolism in the large intestine inhibit the growth of the pathogenic bacterium Clostridium difficile, but when bile acid levels are disrupted by antibiotic treatment, C. difficile is able to flourish. More...
17 Jan 2016

New Drug Research and Development Program to Focus on the Gut Microbiome

Two biotechnology companies have agree to collaborate on a program to develop and commercialize drugs derived from gut bacteria for the treatment of chronic gastrointestinal disorders such as ulcerative colitis and irritable bowel syndrome.  More...
17 Jan 2016
Image: Micrograph of cyclin D1 staining in a mantle cell lymphoma (Photo courtesy of Wikimedia Commons).

Growth of Mantle Cell Lymphoma Slowed by Nanoparticle Transported siRNA

Cancer researchers have used targeted lipid-based nanoparticles to deliver particles of siRNA to silence the gene for production of cyclin D1 in mantle cell lymphoma.  More...
13 Jan 2016
Image: A human nerve cell derived from a patient with Rett syndrome shows significantly decreased levels of KCC2 compared to a control cell (Photo courtesy of Gong Chen laboratory, Pennsylvania State University).

Development of Rett Syndrome Linked to Membrane Transport Protein Deficiency

Neurological disease researchers have found a potential therapeutic approach for the treatment of Rett syndrome that is based on modulation of the calcium transporter protein KCC2.  More...
12 Jan 2016
Image: Representation of a molecule of the Dicer enzyme (Photo courtesy of Wikimedia Commons).

Deleting the Dicer DNA-Repair Enzyme Increases Sensitivity of Cancer Cells to Chemotherapy

Blocking the activity of the enzyme Dicer in rapidly growing cancer cells prevents them from correcting DNA damage, which renders them more sensitive to the action of chemotherapeutic drugs.  More...
12 Jan 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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