We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
LGC Clinical Diagnostics

Download Mobile App




Molecular Diagnostics

Image: Histopathology of pancreatoblastoma showing a large squamoid nest surrounded by sheet of bland monomorphic cells. Many of the squamous cell nuclei are optically clear due to accumulation of biotin (Photo courtesy of Dharam Ramnani, MD).

Pediatric Pancreatic Cancer Diagnosed from cfDNA Fragments in Urine

Although rare, pancreatoblastoma is the most common pancreatic tumor of young children. Carcinoma of acinar cell origin has rarely been reported in older children. Ductal adenocarcinoma and its many variants are the most common pancreatic tumors in adults, but these are exceedingly rare in children. More...
17 Mar 2021
Image: Model of clonal hematopoiesis in normal and inflammatory conditions. In a normal person, hematopoietic stem cells (HSCs) will differentiate and self-renew over the course of a lifetime to replenish the blood system. HSCs will acquire somatic mutations as a result of proliferative stress (Photo courtesy of University of California Irvine).

Clonal Hematopoiesis and Recurrent Mutations Identified in Blood Cancers

Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by detectable hematopoietic-associated gene mutations in a person without evidence of hematologic malignancy. Somatic mutations at hotspots (genetic loci observed to be frequently mutated across cancer patients) often drive or contribute to cancer pathogenesis. More...
16 Mar 2021
Image: Cartoon representation of the molecular structure of the hexokinase-2 (HK2) protein (Photo courtesy of Wikimedia Commons)

Liquid Biopsy Technique Detects Circulating Tumor Cells in Patients with Non-Small Cell Lung Cancer

A liquid biopsy technique based on hexokinase-2, a key enzyme in glucose metabolism, is able to detect circulating tumor cells (CTCs) in patients with non-small cell lung cancer (NSCLC). More...
16 Mar 2021
Image: Presence of lymphocytes within tubular epithelium is one of the pathological features of acute cellular rejection of a kidney transplant (Photo courtesy of Wikimedia Commons)

Analysis of Urinary Exosome RNA Can Diagnose Kidney Transplant Rejection

A panel of mRNA signatures derived from urinary exosomes was shown to be a powerful and noninvasive tool to screen for the body’s rejection of a kidney allograft (a transplant from a genetically non-identical donor). More...
15 Mar 2021
Image: Micrograph of Whipple’s disease. This duodenal biopsy shows the characteristic feature of Whipple’s disease; foamy macrophages are present in the lamina propria cells (Photo courtesy of Nephron).

Whipple’s Disease Pathogen Found in International Diarrhea Patients

Tropheryma whipplei is the causative agent of Whipple’s disease. The organism has also been detected in the feces of healthy or asymptomatic persons and in the feces of patients with diarrhea. Symptoms tend to develop slowly over many years in most people with this disease. More...
11 Mar 2021
Image: Histopathology of Lewy bodies in the midbrain. A Lewy body in a melanized neuron from the substantia nigra. The Lewy body is the spherical body indicated by an arrow (Photo courtesy of Dr. Susan Daniel).

Five Genes Help Predict Lewy Body Dementia

Lewy body dementia usually affects people over 65 years old. Early signs of the disease include hallucinations, mood swings, and problems with thinking, movements, and sleep. Patients who initially have cognitive and behavioral problems are usually diagnosed as having dementia with Lewy bodies, but are sometimes mistakenly diagnosed with Alzheimer’s disease. More...
10 Mar 2021
Image: Histopathological image of sarcoidosis in a lymph node biopsy (Photo courtesy of Wikimedia Commons)

Low Lymphocyte Counts Linked to More Severe Sarcoidosis Inflammation

A recent paper identified unique phenotypes of sarcoidosis and demonstrated the relationship between these phenotypes and inflammatory activity, as measured by serologic markers of inflammation and avidity on 18FDG-PET/CT scan. More...
09 Mar 2021
Gold Member
Blood Gas Analyzer
GEM Premier 7000 with iQM3
Antipsychotic TDM AssaysSaladax Antipsychotic Assays
New
Silver Member
Rubella Infection ELISA
ReQuest RUBELLA IgM ELISA Kit
New
Gold Member
ANA & ENA Screening Assays
ANA and ENA Assays


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
Copyright © 2000-2024 Globetech Media. All rights reserved.