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Hematology

Image: Trichinella sp. found in muscle tissue (Photo courtesy of McGill University)

Laboratory Features of Trichinellosis and Eosinophilia Threshold Determined

Trichinella nativa is a nematode worm, one of the species of the genus Trichinella, found in arctic and subarctic regions. It is highly pathogenic and has a high resistance to freezing. It is encapsulated, and infects a wide variety of mammals and birds. More...
01 Dec 2022
Image: Quantra Hemostasis Analyzer (Photo courtesy of HemoSonics)

Next-Gen POC Whole Blood Hemostasis System Recognizes Specific Needs of EDs and ORs

A next-generation POC hemostasis system leverages innovative medical-grade ultrasound technology to measure the coagulation properties of a whole blood sample. With its rapid results, ease of operation, and dials screen for straightforward interpretation, it is the only whole blood hemostasis testing system specifically cleared for use in POC settings, such as ORs, EDs, and ICUs. More...
01 Dec 2022
Image: The 10X Genomics Chromium Single Cell Gene Expression Solution (Photo courtesy of Technion Israel Institute of Technology)

Immune Microenvironment Characterized in Multiple Myeloma Progression

Multiple myeloma (MM) is a malignant disease of plasma cells (PCs) that reside within the bone marrow (BM). Early alterations within the bone marrow microenvironment that contribute to the progression of MM from its precursor stages could be the key to identifying novel therapeutic approaches. More...
30 Nov 2022
Image: TruSight Lymphoma 40 uses expert-defined content and proven next-generation sequencing (NGS) technology to identify somatic variants associated with lymphomas (Photo courtesy of Illumina)

Tumor Biopsies Analysis Performed on Newly-diagnosed B-cell Neoplasms

Comprehensive genomic analyses of tumor biopsies from patients with newly-diagnosed germinal center B cell (GCB) diffuse large B cell/high grade B cell lymphoma (DLBCL/HGBL) have identified molecular subtypes predictive of inferior survival, which are characterized by somatic mutations that can be detected through clinical laboratory mutation analysis (CLMA). More...
22 Nov 2022
Image: The compact xMAP INTELLIFLEX system is a flow-based, multiplex platform that simplifies the workflow by combining the established performance of xMAP technology (Photo courtesy of Thermo Fisher Scientific)

Assay Developed to Measure Anti-Factor VIII Antibodies

Hemophilia is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding for a longer time after an injury, easy bruising, and an increased risk of bleeding inside joints or the brain. More...
21 Nov 2022
Image: Gating strategy for quantifying peripheral blood neutrophil myeloperoxidase expression (Photo courtesy of Grenoble University Hospital)

Myelodysplastic Syndrome Diagnosed With Peripheral Blood Samples

 Myelodysplastic syndromes (MDS) encompass a heterogeneous group of clonal bone marrow neoplasms, with a median age at diagnosis of 70 years. MDS are characterized by recurrent cytogenetic and molecular abnormalities, morphologic dysplasia for one or more hematopoietic cell lineage and ineffective hematopoiesis. More...
14 Nov 2022
Image: Histopathology of lymph node tissue from a person with idiopathic multicentric Castleman disease. Increased number of blood vessels and smaller germinal centers where immune cells mature in the lymph node, which are two of the pathology features needed to make the diagnosis (Photo courtesy of David Fajgenbaum, MD)

Independent Subtype of Idiopathic Multicentric Castleman Disease Defined

Multicentric Castleman disease (MCD) comprises a heterogeneous group of rare disorders that exhibit generalized symptoms such as swelling of lymph nodes, anemia, fever, and fatigue. Idiopathic multicentric Castleman disease (iMCD) is a type of Castleman disease that is not related to KSHV/HHV8 infection. More...
08 Nov 2022
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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