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Hematology

Image: This photograph shows a close-up of the face of a patient with multiple telangiectasias secondary to hereditary hemorrhagic telangiectasia (Photo courtesy of Dr. P. Marazzi)

Whole Genome Sequences Discriminate Hereditary Hemorrhagic Telangiectasia Phenotypes

The abnormal vascular structures of hereditary hemorrhagic telangiectasia (HHT) often cause severe anemia due to recurrent hemorrhage, but HHT causal genes do not predict the severity of hematological complications. More...
26 Jul 2022
Image: Blood film of a patient with sickle cell/β 0 thalassemia compound heterozygosity shows one sickle cell, boat-shaped cells, target cells, three nucleated red cells, anisocytosis, poikilocytosis (Ke Xu, MD)

DNA Testing Assessed in Childhood Sickle-Cell Anemia Diagnosis

Sickle-cell disease (SCD) is the most common genetic disorder worldwide. SCD patients are homozygous for a recurrent mutation in the HBB-gene resulting in the substitution of a glutamic acid residue with a valine amino acid at position 6 of the beta globin protein (E6V). More...
21 Jul 2022
Image: Storage of red blood cells in alkaline PAGGGM improves metabolism but has no effect on recovery after transfusion (Photo courtesy of openPR)

Transfused RBCs Rapidly Recover From Metabolic Storage Lesions

Directly after red blood cell (RBC) transfusion, a significant number of RBCs are cleared from the circulation; in some patients, up to 38% of the transfused RBCs are cleared in the first 24 hours. More...
20 Jul 2022
Image: Kallestad Anti-dsDNA EIA, Bio-Rad Autoimmune Anti-dsDNA EIA and Bio-Rad Autoimmune EIA Anti-ssDNA. Anti-DNA testing is intended for use in the diagnosis and management of systemic lupus erythematosus (SLE) and certain other rheumatic diseases (Photo courtesy of Bio-Rad)

Anti-Double Stranded DNA Antibodies Diagnose Systemic Lupus Erythematosus

Anti-double-stranded deoxyribonucleic acid antibodies (anti-dsDNA Abs) embrace antibodies with a wide spectrum of fine molecular specificities that are produced persistently in the context of true autoimmunity or transiently in context of infections or other clinical conditions. More...
13 Jul 2022
Image: The new generation Yumizen G800 and G1550 hemostasis analyzers (Photo courtesy of Horiba Medical)

Horiba Showcases New Generation Automated Hemostasis Analyzers at ISTH 2022

Horiba Medical (Kyoto, Japan) showcased the latest additions to its Yumizen G range of hemostasis analyzers and reagents at ISTH 2022 Congress - the premier event in the field of thrombosis and hemostasis - at London’s Excel from 9-13 July 2022. More...
07 Jul 2022
Image: A blood test could predict risk of developing leukemia in elderly years in advance (Photo courtesy of University of Glasgow)

Blood Test Could Predict Future Risk of Developing Leukemia

A blood test could predict risk of developing leukemia in the elderly population years in advance by identifying changes in blood cell production, according to new research. More...
06 Jul 2022
Image: ROTEM delta analysis helps optimize patient treatment and monitor results. Four channels and a comprehensive reagent portfolio aid in the evaluation of coagulopathies (Photo courtesy of Werfen)

Thromboelastometry Predicts Thromboembolic Events in COVID-19 Patients

In addition to severe pulmonary and renal injury, abnormality of hemostasis is recognized as a contributing factor to the severity of the COVID-19. Thromboembolic complications were diagnosed in 31% of patients with COVID-19 infection admitted to an intensive care unit, despite anticoagulation therapy. More...
05 Jul 2022
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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