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Immunology

Image: Stem cell transplants are standard of care for cancers such as leukemia, and lymphoma. MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome (Photo courtesy of Cancer Treatment Centers of America)

Allogeneic Stem Cell Transplants Improve Microbiome, Immune Cells

Past studies have suggested ties between microbial diversity and favorable allogeneic hematopoietic stem cell transplantation (allo-HCT) outcomes, or transplants involving stem cells from healthy donors. The interactions between the gut microbial community and the immune system can influence an individual's response to a bone marrow transplant to treat leukemia, lymphoma, multiple myeloma, and other blood conditions. More...
30 May 2022
Image: UniCel DxI 800 Access Immunoassay System (Photo courtesy of Beckman Coulter)

Autoantibodies Combined With Tumor Markers Detect Lung Cancer

Lung cancer (LC) is one of the most common cancers in the world and is the primary cause of cancer-related death. According to the pathological type, LC can be categorized into small cell LC (SCLC) and non-small cell LC (NSCLC). NSCLC includes squamous cell carcinoma (LSC), adenocarcinoma (LAC), and large cell cancer. More...
26 May 2022
Image: The new Elecsys Androstenedione assay has been compared and evaluated (Photo courtesy of Blood Tests London)

Elecsys Androstenedione Immunoassay Evaluated and Compared

Androstenedione (ASD) is a biomarker used in the diagnostic workup of hyperandrogenism, congenital adrenal hyperplasia, premature adrenarche, and polycystic ovary syndrome (PCOS). Androstenedione is the precursor of testosterone and estrone and is produced in the gonads and adrenal glands. More...
20 May 2022
Image: The Panbio Dengue IgM Capture ELISA is used to detect IgM antibodies to dengue antigen in serum as an aid to clinical laboratory diagnosis of patients with clinical symptoms consistent with dengue fever (Photo courtesy of Abbott)

Combining RDTs Determines Dengue Immune Status

Dengue is an emerging arboviral infectious disease (DENV), transmitted through the bite of an Aedes mosquito that burdens much of the urbanized tropical and subtropical world. Current dengue diagnostics are primarily concerned with capturing active infections, thus no such method exists for determining primary or post-primary DENV infections, at the point of care. More...
18 May 2022
Image: ROC curve AUC and levels of Proenkephalin A 119–159 (PENK) 48 hours after liver transplantation in the need-renal replacement therapy groups (Photo courtesy of University of Sao Paulo)

Biomarker Proenkephalin Investigated in Diagnosis of Acute Kidney Injury

Liver transplantation (LT) is the only treatment available for patients with end-stage liver disease, such as liver cancer or acute and subacute liver failure. Among the various types of postoperative organ damage, acute kidney injury (AKI) is particularly prevalent, developing in 5% to 20% of patients undergoing major non-cardiac surgery. More...
12 May 2022
Image: The Phadia 250 Immunoassay Analyzer, in addition to allergy testing, allows measurement of autoantibodies of more than 20 autoimmune related diseases using the EliA product line (Photo courtesy of Thermo Fisher Scientific)

Biochemical Abnormalities Among Celiac Disease Patients Referred for Antibody Testing

Celiac disease (CD) is a chronic disease occurring in all age groups and affecting approximately 1% of the population, although many cases of CD remain undiagnosed. This condition is caused by an abnormal immune response in genetically susceptible individuals triggered by the ingestion of gluten proteins from wheat, rye and barley. More...
09 May 2022
Image: The Vectra 3 System for Quantitative Pathology Imaging (Photo courtesy of PerkinElmer)

Immunohistochemistry Biomarkers Used to Subtype Gastric Intestinal Metaplasia

Gastric cancer (GC) is the fifth most common and third most lethal cancer globally. Patients with GC are often asymptomatic, with presentation occurring at advanced stage, and a low 5-year survival rate in most countries. Intestinal metaplasia is considered a key pivot point in the Correa model of GC. More...
04 May 2022
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.

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