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Pathology

Image: The TripleTOF 6600 Quadrupole Time-Of-Flight (QTOF) mass analyzer (Photo courtesy of Sciex).

Protein Panel Developed for Early Detection of Lung Cancer

Lung cancer is the most common cause of cancer-related mortality worldwide, characterized by late clinical presentation as 49%–53% of patients are diagnosed at stage IV, and consequently have poor outcomes. More...
18 Sep 2019
Image: The multigene germline panel test prospectively searches for pathogenic or likely pathogenic variants in 30 genes (Photo courtesy of Color Genomics).

Pathogenic Germline Variants Found in Breast Cancer Patients

There is still considerable debate on the value of multigene panel testing for inherited cancer in patients with breast cancer, based on both the prevalence of pathogenic/likely pathogenic (P/LP) variants and any therapeutic implications from genetic test results. More...
18 Sep 2019
Image: This infographic illustrates the connection between the brain, central nervous system and other organs and how they interact with a person\'s gut microbes to show different patterns from people with high blood pressure plus depression; high blood pressure without depression; depression with healthy blood pressure; or healthy subjects without depression or high blood pressure (Photo courtesy of Professor Bruce R. Stevens, PhD).

Gut Bacteria Linked to High Blood Pressure and Depression

The microbiome is the genetic material of all the microbes, bacteria, fungi, protozoa and viruses that live on and inside the human body. The number of genes in all the microbes in one person's microbiome is 200 times the number of genes in the human genome. More...
17 Sep 2019
Image: Lipid-laden macrophages found in patients with vaping-related respiratory illness. Oily lipids are stained red (Photo courtesy of Andrew Hansen, MD, Jordan Valley Medical Center).

Vaping Illness Characterized by Lipid-Laden Cells in Lungs

Lung scans from patients with vaping illness look like a serious viral or bacterial pneumonia, but those tests come back negative. Instead, diagnosis has been based on exclusion of known causes of similar respiratory illnesses combined with knowing the patient has a history of vaping. More...
17 Sep 2019
Image: The i-STAT Alinity system integrates with-patient testing directly into the patient-care pathway, accelerating time to treatment, improving quality and increasing access to care (Photo courtesy of Abbott).

New Blood Test Helps Detect Brain Injury in Minutes

After traumatic brain injury (TBI), plasma concentration of glial fibrillary acidic protein (GFAP) correlates with intracranial injury visible on computerized axial tomography (CT) scan. Some patients with suspected TBI with normal CT findings show pathology on magnetic resonance imaging (MRI). More...
11 Sep 2019

Gout Increases Risk of Advanced Chronic Kidney Disease

Chronic kidney disease (CKD) is a major public health epidemic, with at least 1 in 10 individuals having some degree of kidney impairment, contributing substantially to adverse clinical and economic outcomes. More...
11 Sep 2019
Image: A major new study on the association between blood glucose levels, including HbA1c, and risks of organ impairment in people with type 1 diabetes can make a vital contribution to diabetes care (Photo courtesy of HealthEngine).

Blood Sugar Levels Affect Risks in Type 1 Diabetes

Type 1 diabetes is the predominant form of diabetes diagnosed in childhood and is characterized by increased blood glucose levels resulting from insulin deficiency. More...
11 Sep 2019
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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