New Optical Imaging System Has Fully Adjustable Iris-like Aperture

A newly available state-of-the-art imaging system has been designed specifically to provide a solution for cell biologists requiring an instrument capable of performing high-content cellular assays that include live cell studies, three-dimensional imaging, co-localization studies, or imaging of assays with low signal output.

The GE Healthcare (Little Chalfont, United Kingdom) IN Cell Analyzer 6000 is a high-performance, laser-based, confocal imaging platform designed for the most demanding live cell analysis studies. To this end, the system boasts a proprietary optical system that features a variable, iris-like aperture that mimics the action of the eye and is fully adjustable.

The instrument incorporates the latest generation scientific CMOS camera, which delivers a four times larger field of view with five times less noise than traditional CCD cameras. This technology significantly increases sensitivity and reduces exposure times in order to maximize throughput in screening settings.

The imaging system is described by the manufacturer as being suitable for the most challenging applications by providing flexible imaging for multiplexed assays, enhanced sensitivity for imaging dim assays, and versatility for a wide range of sample types.

The system can handle 6-, 12-, 24-, 48-, 96-, 384-, and 1536-well microplates and is compatible with commercially available laboratory automation systems. In addition, the user can access a manual microscope mode.

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