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Molecular Diagnostics

Image: Ball-and-stick model of the fentanyl molecule in the crystal structure of fentanyl citrate-toluene solvate (Photo courtesy of Wikimedia Commons)

Siemens Healthineers Introduces Autoanalyzer Assay for Monitoring Fentanyl Usage

 A recently introduced diagnostic test for use on clinical chemistry autoanalyzers measures the levels of the opioid drug fentanyl and its primary metabolite norfentanyl. More...
28 Jan 2020
Image: Optic nerve in advanced glaucoma disease (Photo courtesy of Wikimedia Commons)

Genetic Risk Score Detects Glaucoma and Predicts Progression of the Disease

 Establishment of a glaucoma polygenic risk score (PRS) will facilitate the development of a personalized approach for earlier treatment of high-risk individuals, with less intensive monitoring and treatment being possible for lower-risk groups. More...
28 Jan 2020
Image: Acute Myeloid Leukemia: The blasts are medium to large in size and have an elevated nuclear: cytoplasmic ratio. The nuclear chromatin is fine and there are prominent nucleoli. Frequent blasts show indented or “cup-shaped” nuclear contours (Photo courtesy of Elizabeth Courville, MD).

Bone Marrow Donors May Transfer Pathogenic Mutations to Patients

 Clonal hematopoiesis of indeterminate potential, or CHIP, is characterized by the presence of mutant hematopoietic stem cell clones in the bone marrow without overt signs of disease. More...
27 Jan 2020
Image: Photomicrograph of Rickettsia conorii in Vero cells (red rods; magnification ×1,000) (Photo courtesy of Wikimedia Commons)

Identification of Rickettsial Biomarker Facilitates Early Diagnosis of Tick-borne Spotted Fevers

 A protein biomarker has been identified that enables the rapid and specific early diagnosis of tick-borne rickettsial diseases such as Rocky Mountain spotted fever and Mediterranean spotted fever. More...
27 Jan 2020
Image: Photomicrograph of a sputum specimen showing the presence of numerous Mycobacterium tuberculosis bacteria (Photo courtesy of [U.S.] Centers for Disease Control and Prevention)

Genetic Biomarkers Detect Incipient Tuberculosis, Predict Progression of the Disease

 A panel of genetic biomarkers in samples of whole blood has been confirmed as a useful biomarker for the detection of incipient tuberculosis (TB). More...
27 Jan 2020
Image: Figure A shows the location of the lungs and airways in the body. Figure B shows a cross-section of a normal airway. Figure C shows a cross-section of an airway during asthma symptoms (Photo courtesy of [U.S.] National Institute of Health: National Heart, Lung, Blood Institute)

Mutation Present in Genome of Some Asthma Patients Is Responsible for Resistance to Glucocorticoid Treatment

 A genetic variant has been identified that causes depressed lung function among asthma patients and reduces their response to glucocorticoid treatment. More...
23 Jan 2020
Image: One year old boy with Cornelia de Lange syndrome (Photo courtesy of the University of Washington).

Neurodevelopmental Disorders Diagnosed with RNA-Sequencing

 Cornelia de Lange syndrome (CdLS) is a genetic disorder and people with this syndrome experience a range of physical, cognitive, and medical challenges ranging from mild to severe. The syndrome has a widely varied phenotype, meaning people with the syndrome have varied features and challenges. More...
23 Jan 2020
New
Gold Member
ANA & ENA Screening Assays
ANA and ENA Assays
Antipsychotic TDM AssaysSaladax Antipsychotic Assays
New
Thyroid ELISA Kit
AESKULISA a-TPO
New
Quantitative Immunoassay Analyzer
AS050


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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