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Pathology

Image: A cancer cell amongst normal cells. A new biomarker, plectin, has been discovered in cancer stem cells that governs cancer survival and spread (Photo courtesy of Laurie Fickman/ University of Houston).

New Biomarker Discovered for Cancer Stem Cells

 Tumors often contain a small subset of drug-resisting, self-renewing, and highly metastatic cells called tumor initiating cells or cancer stem cells (CSCs). These cells can self-renew, divide asymmetrically, and form tumors in isolation. More...
28 Nov 2019
Image: Growth characteristics of rough and smooth phenotypes of Mycobacterium abscessus on 7H11 agar cultured at 37 °C: representative single rough (left) and smooth (right) colonies (Photo courtesy of Hannover Medical School)

Mycobacterium Infection Found in Gastric Patients’ Stomachs

 Development of gastric diseases such as gastritis, peptic ulcer and gastric cancer is often associated with several biotic and abiotic factors. Helicobacter pylori infection is such a well-known biotic factor. However, not all H. pylori-infected individuals develop gastric diseases and not all individuals with gastric diseases are infected with H. pylori. More...
26 Nov 2019
Image: Novel, high-accuracy blood test can screen for multiple cancers (Photo courtesy of European Society for Medical Oncology)

Novel, High-Accuracy Blood Test Can Screen for Multiple Cancers

 A new targeted methylation-based assay has been developed that is able to screen blood samples for more than 20 types of cancer at all stages, including lung cancer, with high accuracy and it also correctly pinpoints the tissue of origin (TOO). More...
26 Nov 2019
Image: Axio Vert.A1 inverted microscope (Photo courtesy of Carl Zeiss)

Crohn's Disease-Associated Bacteria Tolerate Antibiotics

 Crohn's disease is a chronic disease that causes inflammation and irritation in the digestive tract. The disease is characterized by an imbalance in the intestinal microbiome. In particular, adherent-invasive Escherichia coli (AIEC) strains have been implicated in the disease. More...
26 Nov 2019
Image: Peripheral blood smear from a patient with chronic lymphocytic leukemia (CLL). The lymphocytes with the darkly staining nuclei and scant cytoplasm are the CLL cells (Photo courtesy of VashiDonsk).

Second Malignancy Risk Higher for Some Leukemia Survivors

 Chronic lymphocytic leukemia (CLL) is the most common leukemia diagnosis in adults, with favorable outcomes in majority of patients and a 5-year survival of around 85%. A large proportion of CLL patients may never require treatment, requiring only ongoing surveillance. More...
25 Nov 2019
Image: The Oncotype DX test is a genomic test that analyzes the activity of a group of genes that can affect how a cancer is likely to behave and respond to treatment (Photo courtesy of Michael Jarrett/Genomic Health)

Breast Cancer Recurrence Risk Predicted by Immune-Related Germline Variants

 A single normal cell randomly acquires a series of mutations that allows it to proliferate and to be transformed into a cancer cell (i.e., founding clone), which initiates tumor progression and recurrence. More...
25 Nov 2019
Image: A simple blood test could diagnose breast cancer up to five years before symptoms occur. The presence of autoantibodies, that compliment tumor-associated antigens, help to diagnose breast cancer earlier (Photo courtesy of Oncology Central).

Innovative Blood Test Aids Early Detection of Breast Cancer

 A blood test is being developed that could help detect breast cancer five years before any symptoms become apparent. This method would also be less uncomfortable and more cost effective than traditional mammograms. More...
25 Nov 2019
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.

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