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Pathology

Image: Olympus AI-based pathology diagnostic tool (Photo courtesy of Olympus)

AI-Based Pathology Diagnostic Tool for Gastric Cancer Achieves 100% Sensitivity in Trials

Olympus Life Science (Waltham, MA, USA) has announced the results of its ongoing joint research program to create an AI-based pathology diagnostic tool with the potential to streamline pathologists’ workloads. The diagnostic tool achieved 100% sensitivity and 50% or more specificity for all gastric biopsy pathology specimens analyzed. More...
29 Nov 2021
Image: Absence of nuclear immunohistochemical staining of MSH2 protein (A) and presence of MLH1 protein (B) in urothelial cell carcinoma of the urinary bladder of a patient carrying a germline MSH2 mutation. Observe the nuclear staining in stromal cells as an internal control (Photo courtesy of Radboud University Nijmegen Medical Centre)

Simple Urine Test Detects Urothelial Cancers in Lynch Syndrome Patients

Lynch Syndrome (LS) is an inherited genetic disorder that carries a high risk of cancer. LS is caused by mutations affecting MLH1, MSH2, MSH6 or PMS2 genes. More than one in 300 people have LS but most do not know it and that is equivalent to more than 2,300 new cases every year in the UK. More...
24 Nov 2021
Image: POC pathogen detection system (Photo courtesy of Fraunhofer IPM)

POC System that Requires Single DNA Molecule for Rapid Detection of Multidrug-Resistant Pathogens Unveiled at MEDICA 2021

A new compact device for detecting multidrug-resistant pathogens that performs all stages of the reaction automatically and provides a result within one hour using one single DNA molecule was unveiled at MEDICA 2021. More...
18 Nov 2021
Image: Men with Certain Pathogenic Variants Had a Higher Incidence of Prostate Cancer (Photo courtesy of UrologyAustin)

Men with Certain Pathogenic Variants Had a Higher Incidence of Prostate Cancer

Prostate cancer is one of the major causes of morbidity and mortality in men worldwide. The importance of germline genetic variation for identifying men at increased risk of prostate cancer to enable targeted screening and early detection has become increasingly recognized. More...
17 Nov 2021
Image: The limulus amebocyte lysate (LAL) assay measures endotoxin activity (Photo courtesy of HyCult Biotechnology)

Endotoxemia Genetic Profile Reveals an Association with Thromboembolism and Stroke

Microorganisms are part of the human body, and bacteria or their components often end up in the circulation. One such bacterial component is lipopolysaccharide (LPS), which is a toxin. High concentrations of LPS in the blood cause sepsis. Low LPS levels, known as endotoxemia, cause low-grade inflammation. More...
09 Nov 2021
Illustration

AI Accurately Detects and Diagnoses Colorectal Cancer from Tissue Scans As Well or Better Than Pathologists

Artificial intelligence (A) can accurately detect and diagnose colorectal cancer from tissue scans as well or better than pathologists, according to a new study. More...
05 Nov 2021
Image: The BOND-MAX Fully Automated IHC and ISH Staining System (Photo courtesy of Leica  Microsystems)

Novel Serum Biomarker Investigated for Early Gastric Cancer Diagnosis

Gastric cancer (GC) is one of the most common causes of cancer-related death worldwide. More importantly, most reported GC cases are in developing countries. The high mortality of GC is often due to its nonspecific symptoms and delayed diagnosis. More...
03 Nov 2021
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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