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Immunology

Image: Histological features of collagenous colitis (Photo courtesy of Michael Bonert, MD, FRCPC)

Lack of Autoantibodies Against Related Proteins in Collagenous Colitis

Collagenous colitis (CC) is an inflammatory disorder in the colonic mucosa that predominantly affects elderly women and causes chronic, non-bloody diarrhea with normal or close to normal endoscopic findings. More...
21 Jun 2022
Image: The gold standard for the determination of antinuclear antibodies (ANA) is the indirect immunofluorescence test (IIFT) with human epithelial cells (HEp-2), which is known for its high sensitivity and specificity (Photo courtesy of Euroimmun)

Serological Markers of RA Determined in Patients with aβ2GPI-IgA

Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease. It is characterized by synovial inflammation that can lead to irreversible joint damage and disability when not managed. Biomarkers of RA available for routine clinical use are rheumatoid factors (RF) and anti-cyclic citrullinated peptides (CCP-Ab). More...
14 Jun 2022
Image: The Human P-Selectin ELISA Kit – serum vimentin levels were positively correlated with P-selectin in pediatric severe sepsis (Photo courtesy of MULTI SCIENCES(LIANKE) BIOTECH, CO.,LTD).

Serum Vimentin Predicts Mortality in Pediatric Severe Sepsis

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It is a leading cause of death worldwide in the pediatric population. Vascular hyperpermeability by loss of endothelial barrier integrity is a hallmark of sepsis. More...
14 Jun 2022
Image: With the autoMACS Pro Separator, cells from whole blood or bone marrow can be isolated with minimal hands-on time (Photo courtesy of Miltenyi Biotec)

MRD in AML Detected by Deep Sequencing CD34+ Cells

Monitoring of measurable residual disease (MRD) in patients with acute myeloid leukemia (AML) is predictive of disease recurrence and may identify patients who benefit from treatment intensification. More...
09 Jun 2022
Image: Presepsin has been proposed as a `robust` biomarker of early-onset sepsis (Photo courtesy of Ian Ingram, BA)

Presepsin Proposed as 'Robust' Biomarker of Early-Onset Sepsis

Neonatal early-onset sepsis (EOS) is a severe disease, particularly in preterm infants. Timely diagnosis can be challenging owing to unspecific presentation and questionable performance of the common markers of infection. More...
08 Jun 2022
Image: Immunolocalization of BmR1 homologues showing immunohistochemical results from worm sections that were processed (Photo courtesy of Washington University School of Medicine)

Novel Microfilarial Antigen Diagnoses Lymphatic Filariasis Infections

Lymphatic filariasis is a neglected tropical disease caused by the filarial nematodes Wuchereria bancrofti, Brugia malayi and Brugia timori. Lymphatic filariasis (LF) is a deforming and disabling disease caused by parasitic nematodes that are transmitted by mosquitoes. More...
08 Jun 2022
Image: The Atellica NEPH 630 System is a low- to mid-volume nephelometric protein testing solution that simplifies laboratory operations by unifying instrument, assay, and IT connectivity (Photo courtesy of Siemens Healthineers)

Viral Antigen Detected in Cerebrospinal Fluid of COVID Patients

Neurologic symptoms are common in patients hospitalized with COVID-19 and include anosmia, encephalopathy, encephalitis, and cerebrovascular manifestations, including stroke. The neuroinvasive capacity of SARS-CoV-2 is questionable. More...
31 May 2022
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.

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